Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jacob H. Leung"'
Autor:
Aejin Lee, McKensie L. Mason, Tao Lin, Shashi Bhushan Kumar, Devan Kowdley, Jacob H. Leung, Danah Muhanna, Yuan Sun, Joana Ortega-Anaya, Lianbo Yu, Julie Fitzgerald, A. Courtney DeVries, Randy J. Nelson, Zachary M. Weil, Rafael Jiménez-Flores, Jon R. Parquette, Ouliana Ziouzenkova
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 81 (2021)
Diabetes poses a high risk for debilitating complications in neural tissues, regulating glucose uptake through insulin-dependent and predominantly insulin-independent pathways. Supramolecular nanostructures provide a flexible strategy for combinatori
Externí odkaz:
https://doaj.org/article/2996d2ad0b8b460483f4765e718eac95
Autor:
Kristin I. Stanford, Laisa Gomes-Dias, Tao Lin, Zachary M. Weil, Alessandro Brunetti, Sabrena Noria, No-Joon Song, Bradley Needleman, Jacob H. Leung, Rafael Jiménez-Flores, Aejin Lee, Devan Kowdley, Lisa A. Baer, Joshua J. Blakeslee, Ouliana Ziouzenkova, Jennifer Wall, Jon R. Parquette, Julie Fitzgerald, Yuan Sun, Joana Ortega-Anaya, McKensie L. Mason
Publikováno v:
Biomaterials
Differences in glucose uptake in peripheral and neural tissues account for the reduced efficacy of insulin in nervous tissues. Herein, we report the design of short peptides, referred as amino acid compounds (AAC) with and without a modified side cha
Autor:
Ouliana Ziouzenkova, David DiSilvestro, Rumana Yasmeen, Andrei Maiseyeu, Paolo Fadda, Kefeng Yang, Naresh C. Bal, Lu Xu, Muthu Periasamy, Qiwen Shen, Jacob H. Leung, Devan Kowdley, Aejin Lee
Publikováno v:
The Journal of endocrinology. 239(3)
Adipokine leptin regulates neuroendocrine circuits that control energy expenditure, thermogenesis and weight loss. However, canonic regulators of leptin secretion, such as insulin and malonyl CoA, do not support these processes. We hypothesize that e