Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jacob H. Boysen"'
Publikováno v:
Eukaryotic Cell. 9:532-538
Yeast cells contain two Bro1 domain proteins: Bro1, which is required for endosomal trafficking, and Rim20, which is required for the response to the external pH via the Rim101 pathway. Rim20 associates with endosomal structures under alkaline growth
Autor:
Jacob H. Boysen, Aaron P. Mitchell
Publikováno v:
Molecular Biology of the Cell. 17:1344-1353
Bro1-domain proteins such as yeast Bro1 and mammalian AIP1/Alix are well-established participants in endosome metabolism. The Bro1-domain interacts with endosomal surface protein Snf7/Vps32 in yeast, a subunit of the ESCRT complex. Yeast Bro1-domain
The detection of protein–protein interactions through two-hybrid assays has revolutionized our understanding of biology. The remarkable impact of two-hybrid assay platforms derives from their speed, simplicity, and broad applicability. Yet for many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8e3e7fea1837d3b487dc6a4b6e1f65
https://europepmc.org/articles/PMC2674829/
https://europepmc.org/articles/PMC2674829/
Publikováno v:
Eukaryotic cell. 4(5)
Many fungal pH responses depend upon conserved Rim101p/PacC transcription factors, which are activated by C-terminal proteolytic processing. The means by which environmental pH is sensed by this pathway are not known. Here, we report a screen of the