Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jacob Gerlach"'
Autor:
Scott H. Snyder, Patricia A. Vignaux, Mustafa Kemal Ozalp, Jacob Gerlach, Ana C. Puhl, Thomas R. Lane, John Corbett, Fabio Urbina, Sean Ekins
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Recent advances in machine learning (ML) have led to newer model architectures including transformers (large language models, LLMs) showing state of the art results in text generation and image analysis as well as few-shot learning (FSLC) mo
Externí odkaz:
https://doaj.org/article/35dfdbecd04240859dca01d619069e05
Autor:
Patricia A. Vignaux, Thomas R. Lane, Fabio Urbina, Jacob Gerlach, Ana C. Puhl, Scott H. Snyder, Sean Ekins
Publikováno v:
Chemical Research in Toxicology. 36:188-201
Autor:
Thomas R. Lane, Fabio Urbina, Xiaohong Zhang, Margret Fye, Jacob Gerlach, Stephen H. Wright, Sean Ekins
Publikováno v:
Molecular Pharmaceutics. 19:4320-4332
The uptake transporter OATP1B1 (SLC01B1) is largely localized to the sinusoidal membrane of hepatocytes and is a known victim of unwanted drug-drug interactions. Computational models are useful for identifying potential substrates and/or inhibitors o
Publikováno v:
Drug discovery today. 27(11)
DNA-encoded libraries (DELs) allow starting chemical matter to be identified in drug discovery. The volume of experimental data generated also makes DELs an attractive resource for machine learning (ML). ML allows modeling complex relationships betwe
Publikováno v:
Pharmaceutical Research. 36
Pitt Hopkins Syndrome (PTHS) is a rare genetic disorder caused by mutations of a specific gene, transcription factor 4 (TCF4), located on chromosome 18. PTHS results in individuals that have moderate to severe intellectual disability, with most exhib
Autor:
Sean, Ekins, Jacob, Gerlach, Kimberley M, Zorn, Brett M, Antonio, Zhixin, Lin, Aaron, Gerlach
Publikováno v:
Pharm Res
PURPOSE: Pitt Hopkins Syndrome (PTHS) is a rare genetic disorder caused by mutations of a specific gene, transcription factor 4 (TCF4), located on chromosome 18. PTHS results in individuals that have moderate to severe intellectual disability, with m
Autor:
Christensen, Jacob Gerlach, Høgsbro, Morten, Lauridsen, Anita Guldager, Gothelf, Anita Birgitte, Taheri-Kadkhoda, Zahra, Andersen, Maria, Andersen, Elo, Plaschke, Chritsina Caroline, Wessel, Irene, Homøe, Preben
Publikováno v:
Christensen, J G, Høgsbro, M, Lauridsen, A G, Gothelf, A B, Taheri-Kadkhoda, Z, Andersen, M, Andersen, E, Plaschke, C C, Wessel, I & Homøe, P 2016, Prevention of otitis media with effusion after radiotheraphy in head and neck cancer patients : a randomized controlled trial (Dr. Tuba) . in ECRS 14th Acta Oncologica Symposium European Cancer Rehabilitation & Survivorship Symposium 2016 19 – 20 September : Programme & Abstract Book ., P-60, pp. 83, European Cancer Rehabilitation and Survivorship Symposium, København, Denmark, 19/09/2016 . < https://www.cancer.dk/dyn/resources/File/file/6/5816/1475144498/abstract-book.pdf >
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8a8e2949b773d0835ac5b69173c2fa37
https://vbn.aau.dk/da/publications/2879abb8-a392-495b-96b3-c2a0530945de
https://vbn.aau.dk/da/publications/2879abb8-a392-495b-96b3-c2a0530945de
Autor:
Jacob Gerlach, Iza Goroff
Publikováno v:
SIGCSE
Employers of students trained in computer science and data processing fall largely in three categories: manufacturers of computer equipment, software houses, and finally end users of the computers. Of these categories, most employment opportunities a
Autor:
Thomas R. Lane, Fabio Urbina, Laura Rank, Jacob Gerlach, Olga Riabova, Alexander Lepioshkin, Elena Kazakova, Anthony Vocat, Valery Tkachenko, Stewart Cole, Vadim Makarov, Sean Ekins
Publikováno v:
Mol Pharm
Tuberculosis (TB) is a major global health challenge, with approximately 1.4 million deaths per year. There is still a need to develop novel treatments for patients infected with Mycobacterium tuberculosis (Mtb). There have been many large-scale phen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fb4d0e4b544a4eb0545a81d70682a77
https://infoscience.epfl.ch/record/291312
https://infoscience.epfl.ch/record/291312