Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jacob G Mikkelsen"'
Autor:
Demi van der Horst, Naziia Kurmasheva, Mikkel H. S. Marqvorsen, Sonia Assil, Anna H. F. Rahimic, Christoph F. Kollmann, Leandro Silva da Costa, Qi Wu, Jian Zhao, Eleonora Cesari, Marie B. Iversen, Fanghui Ren, Trine I. Jensen, Ryo Narita, Vivien R. Schack, Bao-cun Zhang, Rasmus O. Bak, Claudio Sette, Robert A. Fenton, Jacob G. Mikkelsen, Søren R. Paludan, David Olagnier
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract DNA is a danger signal sensed by cGAS to engage signaling through STING to activate innate immune functions. The best-studied downstream responses to STING activation include expression of type I interferon and inflammatory genes, but STING
Externí odkaz:
https://doaj.org/article/0db80e2a99374afa9c136a61eb6b74e2
Autor:
Emil Kofod-Olsen, Janni M L Møller, Mariane H Schleimann, Bettina Bundgaard, Rasmus O Bak, Bodil Øster, Jacob G Mikkelsen, Ted Hupp, Per Höllsberg
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59223 (2013)
Infection with human herpesvirus (HHV)-6B alters cell cycle progression and stabilizes tumor suppressor protein p53. In this study, we have analyzed the activity of p53 after stimulation with p53-dependent and -independent DNA damaging agents during
Externí odkaz:
https://doaj.org/article/47cab761a6914845b4a9830b3b2071cd
Autor:
Simone Weiss, Allegra Lord, Bernhard Schmierer, Anne B. Rovsing, Emil A. Thomsen, Jacob G. Mikkelsen, Benedicte Ulhøi, Jakob S. Pedersen, Michael Borre, Karina D. Sørensen
Publikováno v:
Cancer Research. 83:3778-3778
Background: Overtreatment of indolent prostate cancer (PC) and delayed treatment of aggressive PC is common due to suboptimal risk stratification tools, thus warranting identification of novel prognostic biomarkers. Although a few long non-coding RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ffe80c6399b64a2b4818203da7a991d
https://doi.org/10.1158/1538-7445.am2023-3778
https://doi.org/10.1158/1538-7445.am2023-3778
Autor:
Laura Ø. Johnsen, Kathrine A. Friis, Laura B. Ryø, Jacob G. Mikkelsen, Thomas B. Lindhardt, Rasmus W. Knopper, Brian Hansen, Jeppe Praetorius, Helle H. Damkier
Publikováno v:
Johnsen, L, Friis, K A, Ryø, L B, Mikkelsen, J G, Lindhardt, T B, Knopper, R W, Hansen, B, Praetorius, J & Damkier, H H 2022, ' Regulation of Ncbe in the Choroid Plexus of Mice after Hemorrhage-Induced Hydrocephalus ', The FASEB Journal, vol. 36, no. S1 . https://doi.org/10.1096/fasebj.2022.36.S1.R3405
The choroid plexus (CP) is a small tissue located inside brain ventricles. It is responsible for the production of most of the cerebrospinal fluid (CSF); approximately 500 mL of CSF per day in the adult human [1, 2]. CSF production occurs as a net re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92114a4730b6fbab3ed0fd3e954f467c
https://doi.org/10.1096/fasebj.2022.36.s1.r3405
https://doi.org/10.1096/fasebj.2022.36.s1.r3405
Autor:
Christopher J.A. Duncan, Morten K. Skouboe, Sophie Howarth, Anne K. Hollensen, Rui Chen, Malene L. Børresen, Benjamin J. Thompson, Jarmila Stremenova Spegarova, Catherine F. Hatton, Frederik F. Stæger, Mette K. Andersen, John Whittaker, Søren R. Paludan, Sofie E. Jørgensen, Martin K. Thomsen, Jacob G. Mikkelsen, Carsten Heilmann, Daniela Buhas, Nina F. Øbro, Jakob T. Bay, Hanne V. Marquart, M. Teresa de la Morena, Joseph A. Klejka, Matthew Hirschfeld, Line Borgwardt, Isabel Forss, Tania Masmas, Anja Poulsen, Francisco Noya, Guy Rouleau, Torben Hansen, Sirui Zhou, Anders Albrechtsen, Reza Alizadehfar, Eric J. Allenspach, Sophie Hambleton, Trine H. Mogensen
Publikováno v:
Duncan, C J A, Skouboe, M K, Howarth, S, Hollensen, A K, Chen, R, Børresen, M L, Thompson, B J, Spegarova, J S, Hatton, C F, Stæger, F F, Andersen, M K, Whittaker, J, Paludan, S R, Jørgensen, S E, Thomsen, M K, Mikkelsen, J G, Heilmann, C, Buhas, D, Øbro, N F, Bay, J T, Marquart, H V, Morena, M T D L, Klejka, J A, Hirschfeld, M, Borgwardt, L, Forss, I, Masmas, T, Poulsen, A, Noya, F, Rouleau, G, Hansen, T, Zhou, S, Albrechtsen, A, Alizadehfar, R, Allenspach, E J, Hambleton, S & Mogensen, T H 2022, ' Life-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic ', Journal of Experimental Medicine, vol. 219, no. 6, e20212427 . https://doi.org/10.1084/jem.20212427
Duncan, C J A, Skouboe, M K, Howarth, S, Hollensen, A K, Chen, R, Børresen, M L, Thompson, B J, Stremenova Spegarova, J, Hatton, C F, Stæger, F F, Andersen, M K, Whittaker, J, Paludan, S R, Jørgensen, S E, Thomsen, M K, Mikkelsen, J G, Heilmann, C, Buhas, D, Øbro, N F, Bay, J T, Marquart, H V, de la Morena, M T, Klejka, J A, Hirschfeld, M, Borgwardt, L, Forss, I, Masmas, T, Poulsen, A, Noya, F, Rouleau, G, Hansen, T, Zhou, S, Albrechtsen, A, Alizadehfar, R, Allenspach, E J, Hambleton, S & Mogensen, T H 2022, ' Life-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic ', The Journal of Experimental Medicine, vol. 219, no. 6, e20212427 . https://doi.org/10.1084/jem.20212427
Duncan, C J A, Skouboe, M K, Howarth, S, Hollensen, A K, Chen, R, Børresen, M L, Thompson, B J, Stremenova Spegarova, J, Hatton, C F, Stæger, F F, Andersen, M K, Whittaker, J, Paludan, S R, Jørgensen, S E, Thomsen, M K, Mikkelsen, J G, Heilmann, C, Buhas, D, Øbro, N F, Bay, J T, Marquart, H V, de la Morena, M T, Klejka, J A, Hirschfeld, M, Borgwardt, L, Forss, I, Masmas, T, Poulsen, A, Noya, F, Rouleau, G, Hansen, T, Zhou, S, Albrechtsen, A, Alizadehfar, R, Allenspach, E J, Hambleton, S & Mogensen, T H 2022, ' Life-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic ', The Journal of Experimental Medicine, vol. 219, no. 6, e20212427 . https://doi.org/10.1084/jem.20212427
Type I interferons (IFN-I) play a critical role in human antiviral immunity, as demonstrated by the exceptionally rare deleterious variants of IFNAR1 or IFNAR2. We investigated five children from Greenland, Canada, and Alaska presenting with viral di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0e93df69405efb9dfa8932bb4d0da2
https://curis.ku.dk/portal/da/publications/lifethreatening-viral-disease-in-a-novel-form-of-autosomal-recessive-ifnar2-deficiency-in-the-arctic(38e5d906-7ed0-4521-981d-02d7dbdab48d).html
https://curis.ku.dk/portal/da/publications/lifethreatening-viral-disease-in-a-novel-form-of-autosomal-recessive-ifnar2-deficiency-in-the-arctic(38e5d906-7ed0-4521-981d-02d7dbdab48d).html
Autor:
Lise M. Lindahl, Maria Gluud, Thomas Emmanuel, Emil A. Thomsen, Tengpeng Hu, Anne H. Rittig, Pamela Celis, Veronica Stolearenco, Thorbjørn Krejsgaard, Claus Johansen, Andreas Willerslev-Olsen, Terkild B. Buus, Anders Woetmann, Lars Aagaard, Carsten Geisler, Thomas Litman, Jacob G. Mikkelsen, Niels Odum, Lars Iversen
Publikováno v:
Acta Dermato-Venereologica, Vol 100, Iss 16, p adv00270 (2020)
A prognostic 3-miRNA classifier for early-stage mycosis fungoides has been developed recently, with miR-106b providing the strongest prognostic power. The aim of this study was to investigate the molecular function of miR-106b in mycosis fungoides di
Externí odkaz:
https://doaj.org/article/821b7b66f3684bb68c54db99e72161f7
Publikováno v:
BioTechniques, Vol 48, Iss 4, Pp 313-316 (2010)
For cellular and animal transgenesis, FLP- and Cre-recombinase gene capture systems are highly effective to provide stable integration of a donor plasmid carrying the transgene cassette of interest into an engineered genomic locus in a given cell lin
Externí odkaz:
https://doaj.org/article/25be8571660542129cc475f1ca5f7f10