Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Jacob F. Bentzon"'
Autor:
Emiel P. C. van der Vorst, Sanne L. Maas, Kosta Theodorou, Linsey J. F. Peters, Han Jin, Timo Rademakers, Marion J. Gijbels, Mat Rousch, Yvonne Jansen, Christian Weber, Michael Lehrke, Corinna Lebherz, Daniela Yildiz, Andreas Ludwig, Jacob F. Bentzon, Erik A. L. Biessen, Marjo M. P. C. Donners
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
IntroductionThe transmembrane protease A Disintegrin And Metalloproteinase 10 (ADAM10) displays a “pattern regulatory function,” by cleaving a range of membrane-bound proteins. In endothelium, it regulates barrier function, leukocyte recruitment
Externí odkaz:
https://doaj.org/article/f70375b98dbc4f308c54dc71482a5393
Autor:
Jeong Shim, MD, Christian Bo Poulsen, MD, PhD, Mette K. Hagensen, MSc, PhD, Torben Larsen, MSc, PhD, Peter M.H. Heegaard, MSc, PhD, Christina Christoffersen, MD, PhD, DMSc, Lars Bolund, MD, DMSc, Mette Schmidt, DVM, PhD, Ying Liu, MSc, PhD, Juan Li, MSc, PhD, Rong Li, MSc, PhD, Henrik Callesen, DVM, PhD, DrVetSci, Jacob F. Bentzon, MD, PhD, Charlotte B. Sørensen, MSc, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 2, Iss 5, Pp 591-600 (2017)
Deficiency of apolipoprotein E (APOE) causes familial dysbetalipoproteinemia in humans resulting in a higher risk of atherosclerotic disease. In mice, APOE deficiency results in a severe atherosclerosis phenotype, but it is unknown to what extent thi
Externí odkaz:
https://doaj.org/article/91a50e6a7df8447b9e92ca5860a9a261
Autor:
Esmeralda A. Lewis, Rocío Muñiz-Anquela, Ibon Redondo-Angulo, Leticia González-Cintado, Verónica Labrador-Cantarero, Jacob F. Bentzon
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 43:637-649
Background: To cause atherosclerosis, LDLs (low-density lipoproteins) must first pass through the endothelium and then become retained in the arterial matrix. Which of these two processes is rate-limiting and predicts the topography of plaque formati
Autor:
Jeong T Shim, Nikolaj Schmidt, Paula Nogales, Torben Larsen, Charlotte B Sørensen, Jacob F Bentzon
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234131 (2020)
BACKGROUND:Low plasma testosterone, either spontaneous or as a result of androgen deprivation therapy for prostate cancer, is associated with an increased risk of cardiovascular events. The underlying mechanism in humans is not understood. Experiment
Externí odkaz:
https://doaj.org/article/f65aee371fe54e518e7ea8b1d7bd2b44
Autor:
Irene Fernández-Barahona, Irati Aiestaran-Zelaia, Jacob F. Bentzon, Fernando Herranz, Jesús Ruiz-Cabello, Juan Pellico, Lydia Martínez-Parra, María J. Sánchez-Guisado, Lucía Gutiérrez, María Muñoz-Hernando, Ignacio R. Rodriguez
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
ACS Applied Materials & Interfaces
Pellico, J, Fernández-barahona, I, Ruiz-Cabello, J, Gutiérrez, L, Muñoz-Hernando, M, Sánchez-Guisado, M J, Aiestaran-Zelaia, I, Martínez-Parra, L, Rodríguez, I, Bentzon, J F & Herranz, F 2021, ' HAP-Multitag, a PET and Positive MRI Contrast Nanotracer for the Longitudinal Characterization of Vascular Calcifications in Atherosclerosis ', ACS Applied Materials and Interfaces, vol. 13, no. 38, pp. 45279-45290 . https://doi.org/10.1021/acsami.1c13417
instname
ACS Applied Materials & Interfaces
Pellico, J, Fernández-barahona, I, Ruiz-Cabello, J, Gutiérrez, L, Muñoz-Hernando, M, Sánchez-Guisado, M J, Aiestaran-Zelaia, I, Martínez-Parra, L, Rodríguez, I, Bentzon, J F & Herranz, F 2021, ' HAP-Multitag, a PET and Positive MRI Contrast Nanotracer for the Longitudinal Characterization of Vascular Calcifications in Atherosclerosis ', ACS Applied Materials and Interfaces, vol. 13, no. 38, pp. 45279-45290 . https://doi.org/10.1021/acsami.1c13417
Vascular microcalcifications are associated with atherosclerosis plaque instability and, therefore, to increased mortality. Because of this key role, several imaging probes have been developed for their in vivo identification. Among them, [18F]FNa is
Autor:
Beatriz López-Melgar, Virgina Mass, Paula Nogales, Javier Sánchez-González, Robert Entrekin, Antoine Collet-Billon, Xavier Rossello, Leticia Fernández-Friera, Antonio Fernández-Ortiz, Javier Sanz, Jacob F. Bentzon, Héctor Bueno, Borja Ibáñez, Valentín Fuster
Publikováno v:
López-Melgar, B, Mass, V, Nogales, P, Sánchez-González, J, Entrekin, R, Collet-Billon, A, Rossello, X, Fernández-Friera, L, Fernández-Ortiz, A, Sanz, J, Bentzon, J F, Bueno, H, Ibáñez, B & Fuster, V 2022, ' New 3-Dimensional Volumetric Ultrasound Method for Accurate Quantification of Atherosclerotic Plaque Volume ', JACC: Cardiovascular Imaging, vol. 15, no. 6, pp. 1124-1135 . https://doi.org/10.1016/j.jcmg.2022.01.005
Carotid and femoral plaque burden is a recognized biomarker of cardiovascular disease risk. A new electronic-sweep 3-dimensional (3D)-matrix transducer method can improve the functionality and image quality of vascular ultrasound atherosclerosis imag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::680996c99cff7becdf23e1a676a0fb5c
https://pure.au.dk/portal/da/publications/new-3dimensional-volumetric-ultrasound-method-for-accurate-quantification-of-atherosclerotic-plaque-volume(da55bba1-cc0c-496b-9fd5-b850c3bed9d4).html
https://pure.au.dk/portal/da/publications/new-3dimensional-volumetric-ultrasound-method-for-accurate-quantification-of-atherosclerotic-plaque-volume(da55bba1-cc0c-496b-9fd5-b850c3bed9d4).html
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2419
Induction of atherosclerosis in mice with one or more genetic alterations (e.g., conditional deletion of a gene of interest) has traditionally required crossbreeding with Apoe or Ldlr deficient mice to achieve sufficient hypercholesterolemia. However
Publikováno v:
Methods in Molecular Biology ISBN: 9781071619230
Bjørklund, M M, Bernal, J A & Bentzon, J F 2022, Atherosclerosis Induced by Adeno-Associated Virus Encoding Gain-of-Function PCSK9 . in D Ramji (ed.), Atherosclerosis : Methods in Molecular Biology . Humana Press, New York, Methods in Molecular Biology, vol. 2419, pp. 461-473 . https://doi.org/10.1007/978-1-0716-1924-7_27
Bjørklund, M M, Bernal, J A & Bentzon, J F 2022, Atherosclerosis Induced by Adeno-Associated Virus Encoding Gain-of-Function PCSK9 . in D Ramji (ed.), Atherosclerosis : Methods in Molecular Biology . Humana Press, New York, Methods in Molecular Biology, vol. 2419, pp. 461-473 . https://doi.org/10.1007/978-1-0716-1924-7_27
Induction of atherosclerosis in mice with one or more genetic alterations (e.g., conditional deletion of a gene of interest) has traditionally required crossbreeding with Apoe or Ldlr deficient mice to achieve sufficient hypercholesterolemia. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::626317fa7cf96748960214a5cb6c7c73
https://doi.org/10.1007/978-1-0716-1924-7_27
https://doi.org/10.1007/978-1-0716-1924-7_27
Autor:
Michael Winterdahl, Zahra P. Nasr, Zheer Al-Mashhadi, Martin M. Bjørklund, Jacob F. Bentzon, Lars Poulsen Tolbod, Jørgen Frøkiær, Rozh H Al-Mashhadi, Erling Falk, Lars Ø Bloch
Publikováno v:
Al-Mashhadi, R H, Tolbod, L P, Bloch, L, Bjørklund, M M, Nasr, Z P, Al-Mashhadi, Z, Winterdahl, M, Frøkiær, J, Falk, E & Bentzon, J F 2019, ' 18 Fluorodeoxyglucose Accumulation in Arterial Tissues Determined by PET Signal Analysis ', Journal of the American College of Cardiology, vol. 74, no. 9, pp. 1220-1232 . https://doi.org/10.1016/j.jacc.2019.06.057
Repisalud
Instituto de Salud Carlos III (ISCIII)
Repisalud
Instituto de Salud Carlos III (ISCIII)
BACKGROUND: Arterial 18fluorodeoxyglucose (FDG) positron emission tomography (PET) is considered a measure of atherosclerotic plaque macrophages and is used for quantification of disease activity in clinical trials, but the distribution profile of FD
Autor:
Samuel España, Leticia Rocío González-Cintado, Jacob F Bentzon, Adriana Mota-Cobián, R. A. Mota, Carlos Velasco, Jesús Mateo, Paula Nogales
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 41
Objective: 18 F-sodium fluoride ( 18 F-NaF) positron emission tomography (PET) imaging is thought to visualize active atherosclerotic plaque calcification. This is supported by the binding of 18 F-NaF to plaque calcification ex vivo, but no prior stu