Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jacob Elebro"'
Autor:
Sofie Olsson Hau, Sara Wahlin, Sophie Cervin, Vilgot Falk, Björn Nodin, Jacob Elebro, Jakob Eberhard, Bruce Moran, William M Gallagher, Emelie Karnevi, Karin Jirström
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 8, Iss 1, Pp 65-77 (2022)
Abstract The outlook for patients with pancreatic cancer remains dismal. Treatment options are limited and chemotherapy remains standard of care, leading to only modest survival benefits. Hence, there is a great need to further explore the mechanisti
Externí odkaz:
https://doaj.org/article/636b8c745cbd42caa4d4e025acbae2fc
Autor:
Konstantinos S. Papadakos, Sebastian Lundgren, Chrysostomi Gialeli, Patrick Micke, Artur Mezheyeuski, Jacob Elebro, Karin Jirström, Anna M. Blom
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Cartilage oligomeric matrix protein (COMP) is an emerging regulator of tumor progression. The aim of this study was to evaluate the expression of COMP in periampullary adenocarcinoma with respect to prognostic value for survival and relapse, levels o
Externí odkaz:
https://doaj.org/article/5534b29284d848cdb083d0459b839d54
Autor:
Gustav Andersson, Sebastian Lundgren, Margareta Heby, Björn Nodin, Jacob Elebro, Karin Jirström
Publikováno v:
Biomarker Research, Vol 7, Iss 1, Pp 1-14 (2019)
Abstract Background Tamoxifen treatment has previously been reported to confer life-prolonging effects in patients with advanced pancreatic cancer, and most evidently so in women. None of these trials did however include biomarkers, and the relevance
Externí odkaz:
https://doaj.org/article/3c28b24ef1a5403283a27ca2e8fd9c3c
Autor:
Patrick Micke, Carina Strell, Johanna Mattsson, Alfonso Martín-Bernabé, Hans Brunnström, Jutta Huvila, Malin Sund, Fredrik Wärnberg, Fredrik Ponten, Bengt Glimelius, Ina Hrynchyk, Siarhei Mauchanski, Salome Khelashvili, Gemma Garcia-Vicién, David G. Molleví, Per-Henrik Edqvist, Aine O´Reilly, Sara Corvigno, Hanna Dahlstrand, Johan Botling, Ulrika Segersten, Agnieszka Krzyzanowska, Anders Bjartell, Jacob Elebro, Margareta Heby, Sebastian Lundgren, Charlotta Hedner, David Borg, Jenny Brändstedt, Hanna Sartor, Per-Uno Malmström, Martin Johansson, Björn Nodin, Max Backman, Cecilia Lindskog, Karin Jirström, Artur Mezheyeuski
Publikováno v:
EBioMedicine, Vol 65, Iss , Pp 103269- (2021)
Background: The development of a reactive tumour stroma is a hallmark of tumour progression and pronounced tumour stroma is generally considered to be associated with clinical aggressiveness. The variability between tumour types regarding stroma frac
Externí odkaz:
https://doaj.org/article/26bb87848f8f441298d6b26084798ea5
Autor:
Sebastian Lundgren, Patrick Micke, Jacob Elebro, Margareta Heby, Ina Hrynchyk, Björn Nodin, Karin Leandersson, Artur Mezheyeuski, Karin Jirström
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
BackgroundThe clinical management of pancreatic and other periampullary neoplasms remains challenging. In contrast to other cancer types, immunotherapies are largely ineffective, and the reason for the deprived immune response and the immune inhibiti
Externí odkaz:
https://doaj.org/article/ea4a41bb6c554f2aaef0e47ba98293f4
Autor:
Margareta Heby, Sebastian Lundgren, Björn Nodin, Jacob Elebro, Jakob Eberhard, Karin Jirström
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-12 (2018)
Abstract Background Periampullary adenocarcinomas, including pancreatic cancer, are a heterogeneous group of tumors with poor prognosis, where classification into intestinal type (I-type) or pancreatobiliary type (PB-type) is a relevant prognostic fa
Externí odkaz:
https://doaj.org/article/a08aeb58e8e5426c8f0270a501ad8dfd
Autor:
Sebastian Lundgren, Emelie Karnevi, Jacob Elebro, Björn Nodin, Mikael C. I. Karlsson, Jakob Eberhard, Karin Leandersson, Karin Jirström
Publikováno v:
Journal of Translational Medicine, Vol 15, Iss 1, Pp 1-11 (2017)
Abstract Background Dendritic cells (DC) and tumour-associated macrophages (TAM) are essential in linking the innate and adaptive immune response against tumour cells and tumour progression. These cells are also potential target for immunotherapy as
Externí odkaz:
https://doaj.org/article/e70ee1b68bdb47cc82c81ddcf5423cd0
Publikováno v:
Endoscopy International Open, Vol 06, Iss 08, Pp E961-E968 (2018)
Background and study aims Endoscopic submucosal dissection (ESD) is an established method for en bloc resection of large non-pedunculated colorectal lesions in Asia but dissemination of ESD in Western countries is limited. The aim of this study was t
Externí odkaz:
https://doaj.org/article/950574421d004eef95d0077861839f00
Autor:
Sebastian Lundgren, Carl Fredrik Warfvinge, Jacob Elebro, Margareta Heby, Björn Nodin, Agnieszka Krzyzanowska, Anders Bjartell, Karin Leandersson, Jakob Eberhard, Karin Jirström
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156497 (2016)
Natural killer (NK) cells and NK T cells (NKT) are vital parts of tumour immunosurveillance. However, their impact on prognosis and chemotherapy response in periampullary adenocarcinoma, including pancreatic cancer, has not yet been described.Immune
Externí odkaz:
https://doaj.org/article/c10fbbd725d04515b5d1af82eb7a9cef
Autor:
Jacob Elebro, Margareta Heby, Carl Fredrik Warfvinge, Björn Nodin, Jakob Eberhard, Karin Jirström
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153533 (2016)
Periampullary adenocarcinoma, including pancreatic cancer, is a heterogeneous group of tumours with dismal prognosis, for which there is an urgent need to identify novel treatment strategies. The human epithelial growth factor receptors EGFR, HER2 an
Externí odkaz:
https://doaj.org/article/050f7e35469e4f3ea4f6e091070b913b