Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Jacob E. Wang"'
Autor:
Maria K. Dahle, Joanna Agren, Vibeke Sundvold-Gjerstad, Jacob E. Wang, Staale Petter Lyngstadaas, Ingrid B.M. Kolseth
Publikováno v:
Journal of Innate Immunity. 4:176-186
Patients with vitamin A/retinol deficiency are shown to be prone to infections and to suffer from increased inflammation, effects which can be remedied by vitamin A supplements. We aimed to study how human monocytes from the peripheral venous blood o
Publikováno v:
Journal of Trauma: Injury, Infection & Critical Care. 67:624-627
BACKGROUND The aim of this study was to test the hypothesis that inhibitory substances circulating in the patient's serum after trauma might impair leukocyte function by evaluating the effect of such serum on cytokine release in a whole blood model.
Publikováno v:
Journal of Organ Dysfunction. 5:38-50
Herein we review some of the existing knowledge on how the intracellular signaling mediator cyclic adenosine monophosphate (cAMP) regulates mechanisms involved in sepsis and septic shock, focusing on inflammation and hemodynamics. Elevating cAMP by i
Autor:
Jacob E. Wang, Pal F. Jørgensen, Ståle Petter Lyngstadaas, Tom Erik Ruud, T. Scholz, Ansgar O. Aasen, Finn P. Reinholt, R. Yngvar Gundersen
Publikováno v:
Surgical Infections. 9:161-169
Periodontitis is the primary clinical indication for enamel matrix derivative (EMD). Recent investigations, showing that EMD inhibits the production of tumor necrosis factor-alpha (TNF-alpha) when added to human whole blood, indicate a novel role for
Publikováno v:
Journal of Investigative Surgery. 21:255-260
Trauma is associated with immune paresis which may predispose to postoperative sepsis. We characterized the ex vivo cytokine responses to bacterial cell wall components in whole blood from 8 patients undergoing a major musculoskeletal trauma in the f
Publikováno v:
Journal of Orthopaedic Research. 25:1395-1400
Studies with ex vivo stimulation of whole blood samples from injured patients have revealed a diminished production capacity for a broad range of secretory products, including inflammatory cytokines. Recent interest has focused on the release of medi
Publikováno v:
Journal of Orthopaedic Research. 25:262-266
Stahylococcus aureus is the common organism causing musculoskeletal infectons. Stahylococcus aureus peptidoglycan (SaPG) has been identified to increase the acute inflammatory response to wounding, increase reparative granulation tissue, and improve
Autor:
Ansgar O. Aasen, Yunyong Wang, Jon Fredrik Stuestøl, Jacob E. Wang, Petter K. Risøe, Maria K. Dahle
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1772:32-39
Signals that elevate intracellular levels of cyclic adenosine monophosphate (cAMP) are among the factors that control lipopolysaccharide (LPS)-mediated inflammatory mediator production by macrophages. cAMP signaling is also involved in maintaining bo
Publikováno v:
Scandinavian Journal of Immunology. 64:61-68
Previous studies have implicated a role of bacterial DNA, containing unmethylated cytosine-phosphate-guanosine (CpG) motifs, in the initiation of systemic inflammation. This is based on the ability of CpG-DNA to act in synergy with lipopolysaccharide
Autor:
Jon Fredrik Stuestøl, Anders E Myhre, Ansgar O. Aasen, Per Lilleaasen, Jacob E. Wang, Christoph Thiemermann, Maria K. Dahle, Simon J. Foster, Ståle Petter Lyngstadaas
Publikováno v:
Journal of Periodontal Research. 41:208-213
BACKGROUND AND OBJECTIVE Enamel matrix derivative (EMD), extracted from porcine tooth buds, has been shown to promote periodontal healing in patients with severe periodontitis. This involves modulation of the inflammatory response followed by the ons