Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jacob E. Larson"'
Autor:
Jacob E. Larson, P. Brian Hardy, Noah K. Schomburg, Xiaodong Wang, Dmitri Kireev, Kent L. Rossman, Kenneth H. Pearce
Publikováno v:
SLAS Discovery, Vol 28, Iss 1, Pp 39-47 (2023)
Mutations in the small GTPase protein KRAS are one of the leading drivers of cancers including lung, pancreatic, and colorectal, as well as a group of developmental disorders termed “Rasopathies”. Recent breakthroughs in the development of mutant
Externí odkaz:
https://doaj.org/article/d51a173c0d3d402c8c67f70bb132faf6
Autor:
Jacob E. Larson, P. Brian Hardy, Noah K. Schomburg, Xiaodong Wang, Dmitri Kireev, Kent L. Rossman, Kenneth H. Pearce
Publikováno v:
SLAS discovery : advancing life sciences RD.
Mutations in the small GTPase protein KRAS are one of the leading drivers of cancers including lung, pancreatic, and colorectal, as well as a group of developmental disorders termed "Rasopathies". Recent breakthroughs in the development of mutant-spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::320fce79cd752e69faed1f79a5f427be
https://pubmed.ncbi.nlm.nih.gov/36563789
https://pubmed.ncbi.nlm.nih.gov/36563789
Autor:
Andre S. Godoy, Victoria A Haberman, Ana C. Puhl, Leslie V. Parise, Jacob E. Larson, Stephen V. Frye, Jonathan W. Bogart, Kenneth H. Pearce, Tina M. Leisner, Jacqueline Norris-Drouin, Stephanie H. Cholensky, Albert A. Bowers
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
ACS Chem Biol
Universidade de São Paulo (USP)
instacron:USP
ACS Chem Biol
Calcium and integrin binding protein 1 (CIB1) is an EF-hand-containing, small intracellular protein that has recently been implicated in cancer cell survival and proliferation. In particular, CIB1 depletion significantly impairs tumor growth in tripl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260d717507541df8df0aa4ad214c4937
Autor:
Vikas Tyagi, Devon R. Blake, Richard G. Hodge, Xiaodong Wang, Jacob E. Larson, Daowei Huang, Kenneth H. Pearce, Channing J. Der, Lee M. Graves, Angelina V. Vaseva, Thomas S. K. Gilbert, Stephen V. Frye, Laura E. Herring, Adrienne D. Cox, McKenzie P. Kline, Michael J. Emanuele, Gabrielle C. Whiten
Publikováno v:
Science signaling. 12(590)
Stabilization of the MYC oncoprotein by KRAS signaling critically promotes the growth of pancreatic ductal adenocarcinoma (PDAC). Thus, understanding how MYC protein stability is regulated may lead to effective therapies. Here, we used a previously d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8514977272864766f6186af1858eb8af
https://pubmed.ncbi.nlm.nih.gov/31311847
https://pubmed.ncbi.nlm.nih.gov/31311847