Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jacob E. Gillis"'
Autor:
Martin W. LaFleur, Thao H. Nguyen, Matthew A. Coxe, Kathleen B. Yates, Justin D. Trombley, Sarah A. Weiss, Flavian D. Brown, Jacob E. Gillis, Daniel J. Coxe, John G. Doench, W. Nicholas Haining, Arlene H. Sharpe
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
The use of functional genomics in primary immune cells has been limited by inefficient vector delivery and risk of perturbing cell states. Here the authors present CHimeric IMmune Editing (CHIME) for in vivo evaluation of gene function and pooled scr
Externí odkaz:
https://doaj.org/article/f4cc26f0a06e487587662b0cfb8d4512
Publikováno v:
Journal of Allergy and Clinical Immunology. 151:1169-1177
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a0f567b2ed427d015c770136eb83d60
https://doi.org/10.1016/j.jaci.2023.03.013
https://doi.org/10.1016/j.jaci.2023.03.013
Autor:
Arlene H. Sharpe, Marcia C. Haigis, Justin D. Trombley, Vikram R. Juneja, Kiran Kurmi, Cong-Hui Yao, Alison E. Ringel, Martin W. LaFleur, Isaac S. Harris, Emily F. Gaudiano, Thao H. Nguyen, Tara Muijlwijk, Jacob E. Gillis, Jefte M. Drijvers
Supplementary Figure and Table Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5626481bdf20fe17e9420d14ae280ac8
https://doi.org/10.1158/2326-6066.22543842.v1
https://doi.org/10.1158/2326-6066.22543842.v1
Autor:
Arlene H. Sharpe, Marcia C. Haigis, Justin D. Trombley, Vikram R. Juneja, Kiran Kurmi, Cong-Hui Yao, Alison E. Ringel, Martin W. LaFleur, Isaac S. Harris, Emily F. Gaudiano, Thao H. Nguyen, Tara Muijlwijk, Jacob E. Gillis, Jefte M. Drijvers
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ed5bd45f25fdeb87ae7c177752dece
https://doi.org/10.1158/2326-6066.22543839.v1
https://doi.org/10.1158/2326-6066.22543839.v1
Autor:
Arlene H. Sharpe, Marcia C. Haigis, Justin D. Trombley, Vikram R. Juneja, Kiran Kurmi, Cong-Hui Yao, Alison E. Ringel, Martin W. LaFleur, Isaac S. Harris, Emily F. Gaudiano, Thao H. Nguyen, Tara Muijlwijk, Jacob E. Gillis, Jefte M. Drijvers
Supplementary Table S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d3ee59855a43f56797cd02ff8922fe4
https://doi.org/10.1158/2326-6066.22543836.v1
https://doi.org/10.1158/2326-6066.22543836.v1
Autor:
Arlene H. Sharpe, Marcia C. Haigis, Justin D. Trombley, Vikram R. Juneja, Kiran Kurmi, Cong-Hui Yao, Alison E. Ringel, Martin W. LaFleur, Isaac S. Harris, Emily F. Gaudiano, Thao H. Nguyen, Tara Muijlwijk, Jacob E. Gillis, Jefte M. Drijvers
All dose-response curves. Dose-response curves for all library compounds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe0979e1b7484e2e9469ad43c6a3357
https://doi.org/10.1158/2326-6066.22543845.v1
https://doi.org/10.1158/2326-6066.22543845.v1
Autor:
Arlene H. Sharpe, Marcia C. Haigis, Justin D. Trombley, Vikram R. Juneja, Kiran Kurmi, Cong-Hui Yao, Alison E. Ringel, Martin W. LaFleur, Isaac S. Harris, Emily F. Gaudiano, Thao H. Nguyen, Tara Muijlwijk, Jacob E. Gillis, Jefte M. Drijvers
Metabolic constraints in the tumor microenvironment constitute a barrier to effective antitumor immunity and similarities in the metabolic properties of T cells and cancer cells impede the specific therapeutic targeting of metabolism in either popula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c0136f14266cee38042c4d6aaa2846
https://doi.org/10.1158/2326-6066.c.6550425.v1
https://doi.org/10.1158/2326-6066.c.6550425.v1
Autor:
Vikram R. Juneja, Arlene H. Sharpe, Isaac S. Harris, Jacob E. Gillis, Emily F. Gaudiano, Marcia C. Haigis, Thao H. Nguyen, Alison E. Ringel, Tara Muijlwijk, Jefte M. Drijvers, Martin W. LaFleur, Cong-Hui Yao, Kiran Kurmi, Justin D. Trombley
Publikováno v:
Cancer Immunology Research. 9:184-199
Metabolic constraints in the tumor microenvironment constitute a barrier to effective antitumor immunity and similarities in the metabolic properties of T cells and cancer cells impede the specific therapeutic targeting of metabolism in either popula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::551cf95d46e57f86ad2f5da3330eece6
https://doi.org/10.1158/2326-6066.cir-20-0384
https://doi.org/10.1158/2326-6066.cir-20-0384
Autor:
Kathleen B. Yates, W. Nicholas Haining, Thao H. Nguyen, Rose Al Abosy, Debattama R. Sen, Arlene H. Sharpe, Gordon J. Freeman, Matthew A. Coxe, Jacob E. Gillis, Emily F. Gaudiano, Brian C. Miller, Martin W. LaFleur
Publikováno v:
Nature Immunology. 20:1335-1347
CD8+ T cell exhaustion is a state of dysfunction acquired in chronic viral infection and cancer, characterized by the formation of Slamf6+ progenitor exhausted and Tim-3+ terminally exhausted subpopulations through unknown mechanisms. Here we establi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::992756eca413d6aee6ab35f18e3ef5b5
https://doi.org/10.1038/s41590-019-0480-4
https://doi.org/10.1038/s41590-019-0480-4
Autor:
Jefte M, Drijvers, Jacob E, Gillis, Tara, Muijlwijk, Thao H, Nguyen, Emily F, Gaudiano, Isaac S, Harris, Martin W, LaFleur, Alison E, Ringel, Cong-Hui, Yao, Kiran, Kurmi, Vikram R, Juneja, Justin D, Trombley, Marcia C, Haigis, Arlene H, Sharpe
Publikováno v:
Cancer Immunol Res
Metabolic constraints in the tumor microenvironment constitute a barrier to effective anti-tumor immunity and similarities in the metabolic properties of T cells and cancer cells impede the specific therapeutic targeting of metabolism in either popul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5889aa75cd50f2d019b9006ae7bbf1b5
https://pubmed.ncbi.nlm.nih.gov/33277233
https://pubmed.ncbi.nlm.nih.gov/33277233