Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jacob E Koskimaki"'
Autor:
Elena V Rosca, Marie-France Penet, Noriko Mori, Jacob E Koskimaki, Esak Lee, Niranjan B Pandey, Zaver M Bhujwalla, Aleksander S Popel
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111901 (2014)
We investigated the application of a mimetic 20 amino acid peptide derived from type IV collagen for treatment of breast cancer. We showed that the peptide induced a decrease of proliferation, adhesion, and migration of endothelial and tumor cells in
Externí odkaz:
https://doaj.org/article/1a4e8c7b38bc4547866445faf3996f0d
Autor:
Mary E. Charlton, Amanda R. Kahl, Bradley D. McDowell, Robert S. Miller, George Komatsoulis, Jacob E. Koskimaki, Donna R. Rivera, Kathleen A. Cronin
Publikováno v:
JCO Clin Cancer Inform
PURPOSE To evaluate the completeness of information for research and quality assessment through a linkage between cancer registry data and electronic health record (EHR) data refined by ASCO's health technology platform CancerLinQ. METHODS A probabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1095b082f1f17838bcb2be57a873a0c2
https://europepmc.org/articles/PMC9088237/
https://europepmc.org/articles/PMC9088237/
Autor:
Danielle Potter, Raven Brothers, Andrej Kolacevski, Jacob E. Koskimaki, Amy McNutt, Robert S. Miller, Jatin Nagda, Anil Nair, Wendy S. Rubinstein, Andrew K. Stewart, Iris J. Trieb, George A. Komatsoulis
Publikováno v:
JCO Clin Cancer Inform
PURPOSE ASCO, through its wholly owned subsidiary, CancerLinQ LLC, developed CancerLinQ, a learning health system for oncology. A learning health system is important for oncology patients because less than 5% of patients with cancer enroll in clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42b8c2a8a9972ed81f4223d5de314163
https://pubmed.ncbi.nlm.nih.gov/33104389
https://pubmed.ncbi.nlm.nih.gov/33104389
Publikováno v:
Industrial Biotechnology. 9:185-195
Many algae species exhibit phenotypes that are of great interest for industrial applications. Systems biology approaches including large-scale metabolic reconstructions can guide and enhance production of biobased commodities such as fuel and human t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4b8c5c7a62ea3e2bbc0f8e2da5d9039
https://doi.org/10.1089/ind.2013.0012
https://doi.org/10.1089/ind.2013.0012
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 2, Pp 112-124 (2013)
Angiogenesis, the formation of new blood vessels from preexisting blood vessels, is a process that supports tumor growth and metastatic dissemination. Lymphangiogenesis also facilitates metastasis by increasing dissemination through the lymphatic ves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8b63b92a19deaaf6692472d3ec1210a
http://www.sciencedirect.com/science/article/pii/S147655861380022X
http://www.sciencedirect.com/science/article/pii/S147655861380022X
Autor:
William Chen, Elena V. Rosca, Niranjan B. Pandey, Esak Lee, Aleksander S. Popel, Jacob E. Koskimaki, Corban G. Rivera
Publikováno v:
Angiogenesis. 16:159-170
Angiogenesis is central to many physiological and pathological processes. Here we show two potent bioinformatically-identified peptides, one derived from collagen IV and translationally optimized, and one from a somatotropin domain-containing protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d659aa458ee9229c0d149cd00fc8712
https://doi.org/10.1007/s10456-012-9308-7
https://doi.org/10.1007/s10456-012-9308-7
Publikováno v:
Anti-Cancer Drugs. 23:706-712
Peptides are receiving increasing attention as therapeutic agents due to their high binding specificity and versatility to be modified as targeting or carrier molecules. Particularly, peptides with antiangiogenic activity are of high interest because
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::146498002987250154b634b7a3162bfc
https://doi.org/10.1097/cad.0b013e3283531041
https://doi.org/10.1097/cad.0b013e3283531041
Publikováno v:
Chemical Biology & Drug Design. 80:27-37
Structure-activity relationship (SAR) studies are essential in the generation of peptides with enhanced activity and efficacy as therapeutic agents. In this study, we report a Structure-activity relationship study for a family of mimetic peptides der
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62b013ccf3cc64b17e652dd0fc15bb63
https://doi.org/10.1111/j.1747-0285.2012.01376.x
https://doi.org/10.1111/j.1747-0285.2012.01376.x
Autor:
Niranjan B. Pandey, Jacob E. Koskimaki, Elena V. Rosca, Antonio C. Wolff, Aleksander S. Popel
Publikováno v:
Cancer Biology & Therapy. 12:808-817
Breast cancer is one of the most commonly diagnosed malignancies in women. Despite the remarkable success of mammography screening and use of adjuvant systemic therapy, it is estimated that approximately 200,000 new diagnoses will be made this year a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46afe6213f97ec6830f3d4d3c8a6629e
https://doi.org/10.4161/cbt.12.9.17677
https://doi.org/10.4161/cbt.12.9.17677
Autor:
Niranjan B. Pandey, Aleksander S. Popel, Joel S. Bader, Elena V. Rosca, Jacob E. Koskimaki, Corban G. Rivera
Publikováno v:
Journal of Medicinal Chemistry. 54:6492-6500
Angiogenesis is the growth of new blood vessels from existing vasculature. Excessive vascularization is associated with a number of diseases including cancer. Anti-angiogenic therapies have the potential to stunt cancer progression. Peptides derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a102ff1f232821a628a002a6550c249
https://doi.org/10.1021/jm200114f
https://doi.org/10.1021/jm200114f