Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jacob D. Shaul"'
Publikováno v:
Biochemical and Biophysical Research Communications. 374:592-597
NF-kappaB activation in response to pro-inflammatory stimuli relies upon phosphorylation of IkappaB alpha at serines 32 and 36 by the beta subunit of the IkappaB kinase complex (IKK). In this study, we build upon the observation that highly purified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6c88858169e3edacdeabfd8c7a13072
https://doi.org/10.1016/j.bbrc.2008.07.082
https://doi.org/10.1016/j.bbrc.2008.07.082
Autor:
W. Eric Rogers, De-Bin Huang, Tom Huxford, Jacob D. Shaul, Gourisankar Ghosh, Arthur V. Hauenstein
Publikováno v:
Biochemistry, vol 53, iss 12
Biochemistry
Biochemistry
Catalytic subunits of the IκB kinase (IKK), IKK1/IKKα, and IKK2/IKKβ function in vivo as dimers in association with the necessary scaffolding subunit NEMO/IKKγ. Recent X-ray crystal structures of IKK2 suggested that dimerization might be mediated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::849b6dc32beebcb55f29fd0010b46938
https://escholarship.org/uc/item/9273917j
https://escholarship.org/uc/item/9273917j
