Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jacob D, Johnson"'
Autor:
Loren E. Faulkner, Stacey E. Panagotopulos, Jacob D. Johnson, Laura A. Woollett, David Y. Hui, Scott R. Witting, J. Nicholas Maiorano, W. Sean Davidson
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 6, Pp 1322-1332 (2008)
The ATP binding cassette transporter A-1 (ABCA1) is critical for apolipoprotein-mediated cholesterol efflux, an important mechanism employed by macrophages to avoid becoming lipid-laden foam cells, the hallmark of early atherosclerotic lesions. It ha
Externí odkaz:
https://doaj.org/article/903c0ccd8d83446faf8392dea598e231
Autor:
Fredrick L Eyase, Hoseah M Akala, Luiser Ingasia, Agnes Cheruiyot, Angela Omondi, Charles Okudo, Dennis Juma, Redemptah Yeda, Ben Andagalu, Elizabeth Wanja, Edwin Kamau, David Schnabel, Wallace Bulimo, Norman C Waters, Douglas S Walsh, Jacob D Johnson
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64299 (2013)
Single Nucleotide Polymorphisms (SNPs) in the Pfmdr1, and Pfcrt, genes of Plasmodium falciparum may confer resistance to a number of anti-malaria drugs. Pfmdr1 86Y and haplotypes at Pfcrt 72-76 have been linked to chloroquine (CQ) as well as amodiaqu
Externí odkaz:
https://doaj.org/article/ecedf9a8fc864471a385b8940c1adfdb
Publikováno v:
Medicinal Chemistry Research. 25:690-703
Six novel compounds, 3-nonadec-14′-(Z)-enyl phenol (1a); 4,5-dihydroxy-4,2′-epoxy-5-[16′-Z-18′-E-heneicosenyldiene]-cyclohex-2-enone (2), 2,4,5-trihydroxy-2-[16′-Z-heneicosenyl]-cyclohexanone (3); 4S,6R-dihydroxy-6-[12′-Z-heptadecenyl]-cy
Autor:
Lisa Read, Richard J. Sciotti, Philip L. Smith, Mark Hickman, Max Grogl, Mozna Khraiwesh, Susan E. Leed, Thomas H. Hudson, Norma Roncal, Jacob D. Johnson, Robert Paris
Publikováno v:
The American Journal of Tropical Medicine and Hygiene
Leishmaniasis is a complex tropical disease caused by kinetoplastid parasitic protozoa of the genus Leishmania and is transmitted by the sand fly insect vector. Cutaneous leishmaniasis (CL) is the most common form of this disease, and CL infections o
Autor:
Wallace D. Bulimo, Mabel Imbuga, Benjamin Opot, Fredrick L. Eyase, Jacob D. Johnson, Luicer A. Ingasia, Edwin Kamau, Hoseah M. Akala
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:1818-1821
The prevalence of a genetic polymorphism(s) at codon 268 in the cytochrome b gene, which is associated with failure of atovaquone-proguanil treatment, was analyzed in 227 Plasmodium falciparum parasites from western Kenya. The prevalence of the wild-
Autor:
Angela O. Achieng, Fredrick Eyase, Ben Andagalu, Eunice A. Owiti, Dennis W. Juma, Agnes C. Cheruiyot, Catherine Muriuki, Jacob D. Johnson, Edwin Kamau, Charles Okello, Duke Omariba, Hoseah M. Akala, Luiser A. Ingasia, Redemptah Yeda
Publikováno v:
Journal of Multidisciplinary Healthcare
Hoseah M Akala, Angela O Achieng, Fredrick L Eyase, Dennis W Juma, Luiser Ingasia, Agnes C Cheruiyot, Charles Okello, Duke Omariba, Eunice A Owiti, Catherine Muriuki, Redemptah Yeda, Ben Andagalu, Jacob D Johnson, Edwin Kamau Global Emerging Infectio
Autor:
Fredrick Eyase, Lorna J. Chebon, Jacob D. Johnson, Peninah Muiruri, Ngalah S. Bidii, Benjamin Opot, Wallace D. Bulimo, Redemptah Yeda, Dennis W. Juma, Agnes C. Cheruiyot, Paul Oyieng’ Ang’ienda, Edwin Kamau, Ben Andagalu, Charles Okudo, Jelagat Cheruiyot, Joan Mativo, Luicer A. Ingasia, Angela A. Omondi, Hoseah M. Akala, J.M. Ndegwa
Publikováno v:
Antimicrobial Agents and Chemotherapy. 58:3737-3743
In combination with antibiotics, quinine is recommended as the second-line treatment for uncomplicated malaria, an alternative first-line treatment for severe malaria, and for treatment of malaria in the first trimester of pregnancy. Quinine has been
Publikováno v:
Electronic Journal of Qualitative Theory of Differential Equations, Vol 2014, Iss 3, Pp 1-8 (2014)
We study a higher order singular functional difference equation on $\mathbb{Z}$. Sufficient conditions are obtained for the existence of at least one positive periodic solution of the equation. Our proof utilizes the nonlinear alternative of Leray-Sc
Publikováno v:
Differential Equations and Dynamical Systems. 23:195-208
We consider a higher order functional difference equations on \({\mathbb Z}\) with an eigenvalue parameter \(\lambda \) in the equation. Sufficient conditions are obtained for the existence of at least one or two positive periodic solutions of the eq
Autor:
Elizabeth R. Sharlow, Richard J. Sciotti, Judith Berman, William O. Ellis, Jacob D. Johnson, Max Grogl, Thomas H. Hudson, John S. Lazo, Mark Hickman
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 88:216-221
Cutaneous leishmaniasis is clinically widespread but lacks treatments that are effective and well tolerated. Because all present drugs have been grandfathered into clinical use, there are no examples of a pre-clinical product evaluation scheme that l