Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jacob Bastholm Olesen"'
Autor:
Sara Reis Moura, Ana Beatriz Sousa, Jacob Bastholm Olesen, Mário Adolfo Barbosa, Kent Søe, Maria Inês Almeida
Publikováno v:
Cell Death and Disease, Vol 15, Iss 10, Pp 1-16 (2024)
Abstract Osteoclasts are the only cells able to resorb all the constituents of the bone matrix. While the modulation of osteoclast activity is well established for preventing bone-related diseases, there is an increasing demand for novel classes of a
Externí odkaz:
https://doaj.org/article/cf6a8c4977d54b68890d9f1bd659b1fd
Autor:
Preety Panwar, Jacob Bastholm Olesen, Galia Blum, Jean-Marie Delaisse, Kent Søe, Dieter Brömme
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Cathepsin K (CatK), an essential collagenase in osteoclasts (OCs), is a potential therapeutic target for the treatment of osteoporosis. Using live-cell imaging, we monitored the bone resorptive behaviour of OCs during dose-dependent inhibiti
Externí odkaz:
https://doaj.org/article/92cb3c72ac144f1391fde56b99a57085
Autor:
Lars Folkestad, Fritzen, Maja E., Josefine Tauer, Jacob Bastholm Olesen, Victor Winther, Ivan Duran, Svetlana Komarova, Wouter Nijhuis, Richard Kruse, Kenneth Rogers, Ralph Sakkers, Jean-Marie Delaisse, Kent Soe
Publikováno v:
University of Southern Denmark
Autor:
Troels Bechmann, Kent Søe, Silvia Regina Rogatto, Anaïs Marie Julie Møller, Jonna Skov Madsen, Luisa Matos do Canto Alvim, Jacob Bastholm Olesen, Jean-Marie Delaissé
Publikováno v:
Bone Reports, Vol 13, Iss, Pp 100674-(2020)
Møller, A M J, Delaissé, J-M, Bastholm Olesen, J, Bechmann, T, Madsen, J S, Matos Do Canto Alvim, L, Rogatto, S R & Søe, K 2020, ' Zoledronic acid is not equally potent on osteoclasts generated from different individuals-osteoclasts from smokers are less sensitive ', Bone Reports, vol. 13, no. Suppl., P121 . https://doi.org/10.1016/j.bonr.2020.100674
Møller, A M J, Delaissé, J-M, Bastholm Olesen, J, Bechmann, T, Madsen, J S, Matos Do Canto Alvim, L, Rogatto, S R & Søe, K 2020, ' Zoledronic acid is not equally potent on osteoclasts generated from different individuals-osteoclasts from smokers are less sensitive ', Bone Reports, vol. 13, no. Suppl., P121 . https://doi.org/10.1016/j.bonr.2020.100674
Autor:
Jonna Skov Madsen, Jacob Bastholm Olesen, Jean-Marie Delaissé, Troels Bechmann, Anaïs Marie Julie Møller, Kent Søe
Publikováno v:
JBMR Plus
Marie Julie Møller, A, Delaissé, J-M, Bastholm Olesen, J, Bechmann, T, Madsen, J S & Søe, K 2020, ' Zoledronic acid is not equally potent on osteoclasts generated from different individuals ', JBMR Plus, vol. 4, no. 11, e10412 . https://doi.org/10.1002/jbm4.10412
JBMR Plus, Vol 4, Iss 11, Pp n/a-n/a (2020)
Marie Julie Møller, A, Delaissé, J-M, Bastholm Olesen, J, Bechmann, T, Madsen, J S & Søe, K 2020, ' Zoledronic acid is not equally potent on osteoclasts generated from different individuals ', JBMR Plus, vol. 4, no. 11, e10412 . https://doi.org/10.1002/jbm4.10412
JBMR Plus, Vol 4, Iss 11, Pp n/a-n/a (2020)
Zoledronic acid is a bisphosphonate commonly used to treat bone diseases such as osteoporosis and cancer‐induced bone disease. Patients exhibit a variable sensitivity to zoledronic acid; the underlying explanation for this remains unclear. The obje
Autor:
Anaïs Marie Julie Møller, Luisa Matos do Canto, Jacob Bastholm Olesen, Silvia Regina Rogatto, Jonna Skov Madsen, Jean-Marie Delaissé, Kent Søe
Publikováno v:
International Journal of Molecular Sciences
Marie Julie Møller, A, Delaissé, J-M, Bastholm Olesen, J, Canto, L M D, Rogatto, S R, Madsen, J S & Søe, K 2020, ' Fusion-Potential of Human Osteoclasts in vitro Reflects Age, Menopause, and in vivo Bone Resorption Levels of their Donors : A Possible Involvement of DC-STAMP ', International Journal of Molecular Sciences, vol. 21, no. 17, 6368 . https://doi.org/10.3390/ijms21176368
Volume 21
Issue 17
International Journal of Molecular Sciences, Vol 21, Iss 6368, p 6368 (2020)
Marie Julie Møller, A, Delaissé, J-M, Bastholm Olesen, J, Canto, L M D, Rogatto, S R, Madsen, J S & Søe, K 2020, ' Fusion-Potential of Human Osteoclasts in vitro Reflects Age, Menopause, and in vivo Bone Resorption Levels of their Donors : A Possible Involvement of DC-STAMP ', International Journal of Molecular Sciences, vol. 21, no. 17, 6368 . https://doi.org/10.3390/ijms21176368
Volume 21
Issue 17
International Journal of Molecular Sciences, Vol 21, Iss 6368, p 6368 (2020)
It is well established that multinucleation is central for osteoclastic bone resorption. However, our knowledge on the mechanisms regulating how many nuclei an osteoclast will have is limited. The objective of this study was to investigate donor-rela
Autor:
Anaïs Marie Julie Møller, Jacob Bastholm Olesen, Jonna Skov Madsen, Luisa Matos do Canto, Silvia Regina Rogatto, Kent Søe, Jean-Marie Delaissé, Troels Bechmann
Publikováno v:
Marie Julie Møller, A, Delaissé, J-M, Olesen, J B, Madsen, J S, Matos Do Canto Alvim, L, Bechmann, T, Rogatto, S R & Søe, K 2020, ' Aging and menopause reprogram osteoclast precursors for aggressive bone resorption ', Bone Research, vol. 8, 27 . https://doi.org/10.1038/s41413-020-0102-7
Bone Research, Vol 8, Iss 1, Pp 1-11 (2020)
Bone Research
Bone Research, Vol 8, Iss 1, Pp 1-11 (2020)
Bone Research
Women gradually lose bone from the age of ~35 years, but around menopause, the rate of bone loss escalates due to increasing bone resorption and decreasing bone formation levels, rendering these individuals more prone to developing osteoporosis. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c5e92e80e68eb6e34478bef5079b636
https://findresearcher.sdu.dk:8443/ws/files/170891127/M_ller_et_al._2020_BoneRes_Age_Meno.pdf
https://findresearcher.sdu.dk:8443/ws/files/170891127/M_ller_et_al._2020_BoneRes_Age_Meno.pdf
Autor:
Anaïs Marie Julie Møller, Jean-Marie Delaisse, Troels Bechmann, Jacob Bastholm Olesen, Jonna Skov Madsen, Luisa Matos do Canto, Erik Hugger Jakobsen, Silvia Rogatto, Kent Soe
Publikováno v:
Marie Julie Møller, A, Delaissé, J-M, Bechmann, T, Olesen, J B, Madsen, J S, Canto, L M D, Hugger Jakobsen, E, Rogatto, S R & Søe, K 2020, ' Human osteoclasts generated from different individuals show a highly variable sensitivity to zoledronic acid in vitro – osteoclasts from smokers are less sensitive! ', Danish Bone Research Workshop, Sønderborg, Danmark, 31/01/2020-02/02/2020 .
University of Southern Denmark
Marie Julie Møller, A, Delaissé, J-M, Bechmann, T, Olesen, J B, Madsen, J S, Canto, L M D, Hugger Jakobsen, E, Rogatto, S R & Søe, K 2020, ' Human osteoclasts generated from different individuals show a highly variable sensitivity to zoledronic acid in vitro – osteoclasts from smokers are less sensitive! ', Danish Bone Research Workshop, Sønderborg, Denmark, 31/01/2020-02/02/2020 pp. 3 .
University of Southern Denmark
Marie Julie Møller, A, Delaissé, J-M, Bechmann, T, Olesen, J B, Madsen, J S, Canto, L M D, Hugger Jakobsen, E, Rogatto, S R & Søe, K 2020, ' Human osteoclasts generated from different individuals show a highly variable sensitivity to zoledronic acid in vitro – osteoclasts from smokers are less sensitive! ', Danish Bone Research Workshop, Sønderborg, Denmark, 31/01/2020-02/02/2020 pp. 3 .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1a7d633b7267650d287a051f8ffafb33
https://portal.findresearcher.sdu.dk/da/publications/993a2614-98d2-468e-93db-a9ca98b978f2
https://portal.findresearcher.sdu.dk/da/publications/993a2614-98d2-468e-93db-a9ca98b978f2
Autor:
Jacob Bastholm Olesen, Per Kjærsgaard-Andersen, Kent Søe, Thomas Levin Andersen, Dinisha Cyril Pirapaharan, Jean-Marie Delaissé, Sandra Bjerre Christensen
Publikováno v:
Pirapaharan, D C, Olesen, J B, Andersen, T L, Christensen, S B, Kjærsgaard-Andersen, P, Delaisse, J M & Søe, K 2019, ' Catabolic activity of osteoblast lineage cells contributes to osteoclastic bone resorption in vitro ', Journal of Cell Science, vol. 132, no. 10, jcs229351 . https://doi.org/10.1242/jcs.229351
Osteoblast lineage cells in human bone were recently shown to colonize eroded bone surfaces and to closely interact with osteoclasts. They proved to be identical to reversal cells and are believed to differentiate into bone-forming osteoblasts thereb