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pro vyhledávání: '"Jacob Barnard"'
Autor:
Puri, Kavya Sri Racherla, Katrina Dovalovsky, Meet Patel, Emma Harper, Jacob Barnard, S M Nasifuzzaman, Mason Smith, Riya Sikand, Eva Drinka, Neelu
Publikováno v:
Cancers; Volume 15; Issue 13; Pages: 3461
Osimertinib, an irreversible tyrosine kinase inhibitor, is a first-line therapy in EGFR-mutant NSCLC patients. Prolonged treatment with Osimertinib leads to resistance due to an acquired C797S mutation in the EGFR domain and other mechanisms, such as
Autor:
Jacob Barnard, Emma Harper, Edgar Lopez, Jose Lopez, Iftekhar Ahmad, Joseph Ross, Sandra Martell, William Schulz, Neelu Puri
Publikováno v:
Cancer Research. 83:1981-1981
Background: Lung cancer is the deadliest cancer in the US. In 2022, it is anticipated that there will be 236,740 new cases and 130,180 deaths due to lung cancer in the US. Lung cancer's high mortality rate is largely due to the fact that 5.8% of elig