Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Jacob Bar-Tana"'
Autor:
Marjorie Pick, Eyal Lebel, Sharona Elgavish, Hadar Benyamini, Yuval Nevo, Rachel Hertz, Jacob Bar-Tana, Paola Rognoni, Giampaolo Merlini, Moshe E. Gatt
Publikováno v:
Haematologica, Vol 108, Iss 12 (2023)
Systemic light chain amyloidosis (AL) is a clonal plasma cell disorder characterized by the deposition of misfolded immunoglobulin light chains (LC) as insoluble fibrils in organs. The lack of suitable models has hindered the investigation of the dis
Externí odkaz:
https://doaj.org/article/23f2131fe50a4b018e60fda651734447
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Treatment of multiple myeloma (MM) aims at inducing cell apoptosis by surpassing the limited capacity of MM cells to cope with oxidative stress. MM cell survival may further be suppressed by limiting cellular cholesterol. Long-chain fatty ac
Externí odkaz:
https://doaj.org/article/48da890086fd45d8856e963201073334
Publikováno v:
Cancer & Metabolism, Vol 8, Iss 1, Pp 1-14 (2020)
Abstract Background ErbB2 breast cancer still remains an unmet need due to primary and/or acquired resistance to current treatment strategies. MEDICA compounds consist of synthetic long-chain α,ω-dicarboxylic acids previously reported to suppress b
Externí odkaz:
https://doaj.org/article/2d9a2e781c404d73aab83602a35fe21b
Autor:
Jacob Bar-Tana
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/cb995d6e2e0f4fad830001d52b1523d7
Autor:
Anna Algamas-Dimantov, Dana Davidovsky, Julius Ben-Ari, Jing X. Kang, Irena Peri, Rachel Hertz, Jacob Bar-Tana, Betty Schwartz
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 6, Pp 1056-1070 (2012)
Postnatal intestinal ontogenesis in an animal model of diabesity may recapitulate morphological and transduction features of diabesity-induced intestinal dysplasia and its amelioration by endogenous (n-3) polyunsaturated fatty acids (PUFA). Prolifera
Externí odkaz:
https://doaj.org/article/ce523612b7554d819e6513f5b5bd7e7f
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 5, Pp 868-878 (2012)
Agonist-induced lipolysis of adipose fat is robustly inhibited by insulin or by feedback inhibition by the long-chain fatty acids (LCFA) produced during lipolysis. However, the mode of action of LCFA in suppressing adipose lipolysis is not clear. β,
Externí odkaz:
https://doaj.org/article/a55b92161b0b4ec9ac4d31352c4cc428
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 2, Pp 328-341 (2005)
Microsomal triglyceride transfer protein (MTP) catalyzes the assembly of triglyceride (TG)-rich apolipoprotein B-containing liver (e.g., VLDL) and intestinal (e.g., chylomicron) lipoproteins. The human MTP gene promoter is reported here to associate
Externí odkaz:
https://doaj.org/article/874206eaa58a4964ace42686c4c6fec2
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107364 (2014)
The P70 ribosomal protein S6 kinase 1 (P70S6K1) is activated by the mammalian target of rapamycin (mTORC1) and regulates proliferation, growth, and metabolism. PF-4708671 is a novel, cell-permeable, has been proposed to be a highly specific inhibitor
Externí odkaz:
https://doaj.org/article/3cf93284241f408db183ad6b65467b2d
Autor:
Jacob Bar-Tana
Publikováno v:
Trends in Endocrinology & Metabolism. 34:135-145
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cccb5ff082eaca83336cffb16a51f649
https://doi.org/10.1016/j.tem.2023.01.001
https://doi.org/10.1016/j.tem.2023.01.001
Autor:
Jacob Bar-Tana, Eli Pikarsky, Martha Smets, Elia Smeir, Sarit Ohayon, Rachel Hertz, Udi Gluschnaider
Supplemental Figures S1-S3. c-Src/STAT3 crosstalk of Met-1 cells (S1); c-Src/STAT3 crosstalk of HCC1954 cells (S2); MEDICA amplifies radiation-suppressed clonogenity of HCC1954 cells (S3).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22f0e80aa7b713a659dbc01744e2f079
https://doi.org/10.1158/0008-5472.22403924
https://doi.org/10.1158/0008-5472.22403924
