Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jacob B, Geri"'
Autor:
Padma P. Nanaware, Zohaib N. Khan, Cristina C. Clement, Madhur Shetty, Ines Mota, Ethan S. Seltzer, Monika Dzieciatkowska, Fabia Gamboni, Angelo D’Alessandro, Charles Ng, Manabu Nagayama, Cheryl F. Lichti, Rajesh K. Soni, Jacob B. Geri, Irina Matei, David Lyden, Randy Longman, Theresa T. Lu, Xiaoxiao Wan, Emil R. Unanue, Lawrence J. Stern, Laura Santambrogio
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114311- (2024)
Summary: The lymphatic fluid is the conduit by which part of the tissue “omics” is transported to the draining lymph node for immunosurveillance. Following cannulation of the pre-nodal cervical and mesenteric afferent lymphatics, herein we invest
Externí odkaz:
https://doaj.org/article/957cfb99c70846f691804304c5c2963b
Autor:
Nanaware, Padma P., Khan, Zohaib N., Clement, Cristina C., Shetty, Madhur, Mota, Ines, Seltzer, Ethan S., Dzieciatkowska, Monika, Gamboni, Fabia, D’Alessandro, Angelo, Ng, Charles, Nagayama, Manabu, Lichti, Cheryl F., Soni, Rajesh K., Jacob B. Geri, Matei, Irina, Lyden, David, Longman, Randy, Lu, Theresa T., Wan, Xiaoxiao, Unanue, Emil R., Stern, Lawrence J., Santambrogio, Laura
Publikováno v:
In Cell Reports 25 June 2024 43(6)
Autor:
James V. Oakley, Benito F. Buksh, David F. Fernández, Daniel G. Oblinsky, Ciaran P. Seath, Jacob B. Geri, Gregory D. Scholes, David W. C. MacMillan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(32)
The elucidation of protein interaction networks is critical to understanding fundamental biology as well as developing new therapeutics. Proximity labeling platforms (PLPs) are state-of-the-art technologies that enable the discovery and delineation o
Autor:
Saori Suzuki, Jacob B. Geri, Steve D. Knutson, Harris Bell-Temin, Tomokazu Tamura, David F. Fernández, Gabrielle H. Lovett, Nicholas A. Till, Brigitte L. Heller, Jinchao Guo, David W. C. MacMillan, Alexander Ploss
Publikováno v:
Journal of the American Chemical Society. 144(36)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the infectious agent of the COVID-19 pandemic, remains a global medical problem. Angiotensin-converting enzyme 2 (
Autor:
Benito F. Buksh, Steve D. Knutson, James V. Oakley, Noah B. Bissonnette, Daniel G. Oblinsky, Michael P. Schwoerer, Ciaran P. Seath, Jacob B. Geri, Frances P. Rodriguez-Rivera, Dann L. Parker, Gregory D. Scholes, Alexander Ploss, David W. C. MacMillan
Publikováno v:
J Am Chem Soc
Modern proximity labeling techniques have enabled significant advances in understanding biomolecular interactions. However, current tools primarily utilize activation modes that are incompatible with complex biological environments, limiting our abil
Autor:
Cory H. White, Adam G. Schwaid, Keun Ah Ryu, Olugbeminiyi O. Fadeyi, Beryl X. Li, David W. C. MacMillan, Frances P. Rodriguez-Rivera, James V. Oakley, Dann L. Parker, Jacob B. Geri, Paul Tawa, Tamara Reyes-Robles, Rob C. Oslund, Aaron D. Trowbridge, Barbara E. Dul, Ciaran P. Seath
Publikováno v:
bioRxiv
BioRxiv
BioRxiv
The identification of cellular targets that can be exploited for therapeutic benefit, broadly known as target ID, remains a fundamental goal in drug discovery. In recent years, the application of new chemical and biological technologies that accelera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e7fb28b863a109210656d766c921a8
https://doi.org/10.1101/2021.08.02.454797
https://doi.org/10.1101/2021.08.02.454797
Publikováno v:
Chemical Communications. 55:5119-5122
Difluoromethane (CF2H2) is an ecologically-friendly refrigerant which holds promise as a source of CF2H-. However, the weak acidity (pKa = 35-41) and low stability of the conjugate base have prevented its utilization as a chemical feedstock. In this
Autor:
John T. York, Jacob B. Geri
Publikováno v:
Inorganica Chimica Acta. 483:191-202
The impact of ancillary ligand basicity on the binding and activation of ethylene in a series of [(L)Pd0(C2H4)] and [(L)PdII(C2H4)]2+ complexes (where L = substituted 1,10-phenanthroline ligands) has been studied with density functional theory using
Publikováno v:
Angewandte Chemie. 130:1395-1399
Publikováno v:
Chemical Communications. 54:7790-7793
Modular but geometrically constrained ligands were used to investigate the impact of key ligand design parameters (charge and bite angle) on CO2 hydrogenation and formic acid dehydrogenation activity. These studies yielded an optimized catalyst that