Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jacob Al-Saleem"'
Autor:
Michael P. Martinez, Xiaogang Cheng, Ancy Joseph, Jacob Al-Saleem, Amanda R. Panfil, Marilly Palettas, Wessel P. Dirksen, Lee Ratner, Patrick L. Green
Publikováno v:
Retrovirology, Vol 16, Iss 1, Pp 1-13 (2019)
Abstract Background Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia/lymphoma (ATL) and the neurological disorder HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). The exact mechanism(s) t
Externí odkaz:
https://doaj.org/article/5ea8196afd3b463a8743ece67d955677
Publikováno v:
Retrovirology, Vol 16, Iss 1, Pp 1-12 (2019)
Abstract Human T cell leukemia virus type 1 (HTLV-1) was the first discovered human retrovirus and the etiologic agent of adult T-cell leukemia and HTLV-1-associated myelopathy/tropical spastic paraparesis. Shortly after the discovery of HTLV-1, huma
Externí odkaz:
https://doaj.org/article/74c3728f3c50491d80c513920a933764
Autor:
Jacob Al-Saleem, Wessel P Dirksen, Michael P Martinez, Nikoloz Shkriabai, Mamuka Kvaratskhelia, Lee Ratner, Patrick L Green
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0214059 (2019)
An estimated 10-20 million people worldwide are infected with human T cell leukemia virus type 1 (HTLV-1), with endemic areas of infection in Japan, Australia, the Caribbean, and Africa. HTLV-1 is the causative agent of adult T cell leukemia (ATL) an
Externí odkaz:
https://doaj.org/article/2cea6b511ff5410084ce360f2709625c
Autor:
Amanda R. Panfil, Jacob Al-Saleem, Cory M. Howard, Nikoloz Shkriabai, Mamuka Kvaratskhelia, Patrick L. Green
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Human T-cell leukemia virus type 1 (HTLV-1) encodes a protein derived from the antisense strand of the proviral genome designated HBZ (HTLV-1 basic leucine zipper factor). HBZ is the only viral gene consistently expressed in infected patients and adu
Externí odkaz:
https://doaj.org/article/453624a9dd8043538740eb82dc006556
Autor:
Nathan Dissinger, Nikoloz Shkriabai, Sonja Hess, Jacob Al-Saleem, Mamuka Kvaratskhelia, Patrick L Green
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112762 (2014)
Human T-cell leukemia virus type-1 (HTLV-1) is estimated to infect 15-25 million people worldwide, with several areas including southern Japan and the Caribbean basin being endemic. The virus is the etiological agent of debilitating and fatal disease
Externí odkaz:
https://doaj.org/article/01b5e6986b8541b09f48a865ae7cb6c4
Autor:
Amanda R. Panfil, Jacob Al-Saleem, Cory M. Howard, Jessica M. Mates, Jesse J. Kwiek, Robert A. Baiocchi, Patrick L. Green
Publikováno v:
Viruses, Vol 8, Iss 1, p 7 (2015)
Human T-cell leukemia virus type-1 (HTLV-1) is a tumorigenic retrovirus responsible for development of adult T-cell leukemia/lymphoma (ATLL). This disease manifests after a long clinical latency period of up to 2–3 decades. Two viral gene products,
Externí odkaz:
https://doaj.org/article/11bc1fea87494619b1b5f628a7d71b91
Autor:
Srinivasan Ramakrishnan, Jacob Al-Saleem, Catherine J. Saveson, Natalie A. Ciancetta, Chris Gessner, Qiongqiong Zhou, Roger Granet
Publikováno v:
Journal of Chemical Information and Modeling
The COVID-19 pandemic has motivated researchers all over the world in trying to find effective drugs and therapeutics for treating this disease. To save time, much effort has focused on repurposing drugs known for treating other diseases than COVID-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96bc6a6f56c9475dba741d5fb342ea0c
https://doi.org/10.1021/acs.jcim.1c00642
https://doi.org/10.1021/acs.jcim.1c00642
Autor:
Xiaogang Cheng, Ancy Joseph, Patrick L. Green, Michael P. Martinez, Amanda R. Panfil, Marilly Palettas, Lee Ratner, Jacob Al-Saleem, Wessel P. Dirksen
Publikováno v:
Retrovirology
Retrovirology, Vol 16, Iss 1, Pp 1-13 (2019)
Retrovirology, Vol 16, Iss 1, Pp 1-13 (2019)
Background Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia/lymphoma (ATL) and the neurological disorder HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). The exact mechanism(s) through wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::110a44a1e34fbddcc8e67e4f231278dc
https://pubmed.ncbi.nlm.nih.gov/31864373
https://pubmed.ncbi.nlm.nih.gov/31864373
Autor:
Mamuka Kvaratskhelia, Nikoloz Shkriabai, Lee Ratner, Wessel P. Dirksen, Michael P. Martinez, Patrick L. Green, Jacob Al-Saleem
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 3, p e0214059 (2019)
PLoS ONE, Vol 14, Iss 3, p e0214059 (2019)
An estimated 10-20 million people worldwide are infected with human T cell leukemia virus type 1 (HTLV-1), with endemic areas of infection in Japan, Australia, the Caribbean, and Africa. HTLV-1 is the causative agent of adult T cell leukemia (ATL) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3813e92fefb69af20b8fdc3116d7144e
https://pubmed.ncbi.nlm.nih.gov/30897179
https://pubmed.ncbi.nlm.nih.gov/30897179
Autor:
Hicham H. Baydoun, Nikoloz Shkriabai, Patrick L. Green, Lee Ratner, Jacob Al-Saleem, Mathew Cherian, Mamuka Kvaratskhelia
Publikováno v:
Journal of Biological Chemistry. 290:26270-26281
Human T-cell leukemia virus (HTLV) type 1, the etiological agent of adult T-cell leukemia, expresses the viral oncoprotein Tax1. In contrast, HTLV-2, which expresses Tax2, is non-leukemogenic. One difference between these homologous proteins is the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05728bab08731f4ca652a854ecf55973
https://doi.org/10.1074/jbc.m115.684746
https://doi.org/10.1074/jbc.m115.684746