Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Jacob A. Mayfield"'
Autor:
Malavika Prithviraj, Takehiro Kado, Jacob A. Mayfield, David C. Young, Annie D. Huang, Daisuke Motooka, Shota Nakamura, M. Sloan Siegrist, D. Branch Moody, Yasu S. Morita
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT The intracellular membrane domain (IMD) is a laterally discrete region of the mycobacterial plasma membrane, enriched in the subpolar region of the rod-shaped cell. Here, we report genome-wide transposon sequencing to discover the controller
Externí odkaz:
https://doaj.org/article/071ab252440f496891804f784c00ed5e
Autor:
Melissa Bedard, Sanne van der Niet, Elliott M. Bernard, Gregory Babunovic, Tan-Yun Cheng, Beren Aylan, Anita E. Grootemaat, Sahadevan Raman, Laure Botella, Eri Ishikawa, Mary P. O’Sullivan, Seónadh O’Leary, Jacob A. Mayfield, Jeffrey Buter, Adriaan J. Minnaard, Sarah M. Fortune, Leon O. Murphy, Daniel S. Ory, Joseph Keane, Sho Yamasaki, Maximiliano G. Gutierrez, Nicole van der Wel, D. Branch Moody
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 6 (2023)
Induction of lipid-laden foamy macrophages is a cellular hallmark of tuberculosis (TB) disease, which involves the transformation of infected phagolysosomes from a site of killing into a nutrient-rich replicative niche. Here, we show that a terpenyl
Externí odkaz:
https://doaj.org/article/66ad604010504fdab74173379c2c7ca6
Autor:
Kelly J. Gregory, Amy L. Roberts, Erin M. Conlon, Jacob A. Mayfield, Mary J. Hagen, Giovanna M. Crisi, Brooke A. Bentley, Jeffrey J. Kane, Grace Makari-Judson, Holly S. Mason, Jun Yu, Lihua Julie Zhu, Karl Simin, Jacob P. S. Johnson, Ashraf Khan, Ben R. Schneider, Sallie S. Schneider, D. Joseph Jerry
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-18 (2019)
Abstract Background Atypical breast hyperplasias (AH) have a 10-year risk of progression to invasive cancer estimated at 4–7%, with the overall risk of developing breast cancer increased by ~ 4-fold. AH lesions are estrogen receptor alpha positive
Externí odkaz:
https://doaj.org/article/14367b64f7854897a6a4e3a757b9c8bf
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
The intracellular membrane domain (IMD) in mycobacteria is a spatially distinct region of the plasma membrane with diverse functions. Previous comparative proteomic analysis of the IMD suggested that menaquinone biosynthetic enzymes are associated wi
Externí odkaz:
https://doaj.org/article/445d12f871d949eb81d0e69cbb2af26b
Autor:
Xavier Carette, John Platig, David C. Young, Michaela Helmel, Albert T. Young, Zhe Wang, Lakshmi-Prasad Potluri, Cameron Stuver Moody, Jumei Zeng, Sladjana Prisic, Joseph N. Paulson, Jan Muntel, Ashoka V. R. Madduri, Jorge Velarde, Jacob A. Mayfield, Christopher Locher, Tiansheng Wang, John Quackenbush, Kyu Y. Rhee, D. Branch Moody, Hanno Steen, Robert N. Husson
Publikováno v:
mBio, Vol 9, Iss 2 (2018)
ABSTRACT Tuberculosis is the leading killer among infectious diseases worldwide. Increasing multidrug resistance has prompted new approaches for tuberculosis drug development, including targeted inhibition of virulence determinants and of signaling c
Externí odkaz:
https://doaj.org/article/499cf436426a467c922809513e71e00a
Autor:
Jacob J. Mayfield, Catherine M. Otto
Publikováno v:
Current Cardiology Reports. 25:333-348
Autor:
Mark R. Sullivan, Kerry McGowen, Qiang Liu, Chidiebere Akusobi, David C. Young, Jacob A. Mayfield, Sahadevan Raman, Ian D. Wolf, D. Branch Moody, Courtney C. Aldrich, Alexander Muir, Eric J. Rubin
Publikováno v:
Nature Microbiology. 8:481-497
Publikováno v:
New England Journal of Medicine. 387:67-73
Autor:
Jacob J. Mayfield, Andrew D. Leavitt, Talha Tanriverdi, Krishan Soni, Thomas A. Ports, M. Roselle Abraham
Publikováno v:
Journal of Thrombosis and Thrombolysis. 54:323-329
Autor:
Gunvant R. Chaudhari, Jacob J. Mayfield, Joshua P. Barrios, Sean Abreau, Robert Avram, Jeffrey E. Olgin, Geoffrey H. Tison
Publikováno v:
Scientific reports, vol 13, iss 1
Chest pain is a common clinical complaint for which myocardial injury is the primary concern and is associated with significant morbidity and mortality. To aid providers’ decision-making, we aimed to analyze the electrocardiogram (ECG) using a deep