Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jacob A. Ludin"'
Autor:
Lei Wang, Jacob A. Ludin, Mohan K. Raizada, Michael D. Smeltzer, Helmut Hiller, David J. Pioquinto, Karlena M. Cahill, Eric G. Krause, Michael J. Katovich, Annette D. de Kloet, Erin Bruce
Publikováno v:
Neuropharmacology. 133:85-93
This study used mice to evaluate whether coupling expression of corticotropin-releasing hormone (CRH) and angiotensin converting enzyme 2 (ACE2) creates central interactions that blunt endocrine and behavioral responses to psychogenic stress. Central
Autor:
Jacob A. Ludin, Eric G. Krause, Amy R. Alleyne, Meng Liu, Annette D. de Kloet, Colin Sumners, Shormista Kar, Zachary Winder, David J. Pioquinto, Vermali Rodriguez, Yuma T. Ortiz
Publikováno v:
Hypertens Res
Brain angiotensin-II (Ang-II) type-1 receptors (AT1Rs), which exert profound effects on normal cardiovascular, fluid, and metabolic homeostasis, are overactivated in and contribute to chronic sympathoexcitation and hypertension. Accumulating evidence
Autor:
Charles J. Frazier, Justin A. Smith, Jacob A. Ludin, Mohan K. Raizada, Eric G. Krause, Annette D. de Kloet, Michael J. Katovich, Lei Wang, Dipanwita Pati, Helmut Hiller, S. Paul Oh, David J. Pioquinto
Publikováno v:
Neuropharmacology. 105:114-123
Over-activation of the brain renin-angiotensin system (RAS) has been implicated in the etiology of anxiety disorders. Angiotensin converting enzyme 2 (ACE2) inhibits RAS activity by converting angiotensin-II, the effector peptide of RAS, to angiotens
Autor:
Eric G. Krause, Helmut Hiller, Jacob A. Ludin, Annette D. de Kloet, Justin A. Smith, Lei Wang, Deborah A. Scheuer, Colin Sumners, David J. Pioquinto, U. Muscha Steckelings
Publikováno v:
de Kloet, A D, Wang, L, Ludin, J A, Smith, J A, Pioquinto, D J, Hiller, H, Steckelings, U M, Scheuer, D A, Sumners, C & Krause, E G 2016, ' Reporter mouse strain provides a novel look at angiotensin type-2 receptor distribution in the central nervous system ', Brain Structure and Function (Print Edition), vol. 221, no. 2, pp. 891-912 . https://doi.org/10.1007/s00429-014-0943-1
Angiotensin-II acts at its type-1 receptor (AT1R) in the brain to regulate body fluid homeostasis, sympathetic outflow and blood pressure. However, the role of the angiotensin type-2 receptor (AT2R) in the neural control of these processes has receiv
Autor:
Jennifer L. Bizon, Adam P. Mecca, Phillip F. Ritucci-Chinni, David Greenstein, Fiona A. Desland, Colin Sumners, Cristina Bañuelos, Mary K. Reinhard, Robert W. Regenhardt, Jacob A. Ludin
Publikováno v:
Experimental Physiology. 99:442-453
New Findings What is the central question of this study? Activation of angiotensin-converting enzyme 2, resulting in production of angiotensin-(1–7) and stimulation of its receptor, Mas, exerts beneficial actions in a number cardiovascular diseases
Autor:
Lei Wang, Eric G. Krause, Justin A. Smith, Urlike M Steckelings, Annette D. de Kloet, Jacob A. Ludin, Helmut Hiller, Deborah A. Scheuer, Colin Sumners
Publikováno v:
Hypertension. 68
The role of the angiotensin type-2 receptor (AT2R) in the neural control of cardiovascular homeostasis and hypertension is not well-characterized. Using a BAC transgenic AT2R-enhanced green fluorescent protein (eGFP) reporter mouse, dense localizatio
Autor:
Annette D de Kloet, Lei Wang, Jacob A Ludin, Helmut Hiller, Justin A Smith, David J Pioquinto, Deborah A Scheuer, Ulrike Steckelings, Eric G Krause, Colin Sumners
Publikováno v:
Hypertension. 64
It is established that angiotensin-II acts at its type-1 receptor (AT1R) in the brain to increase sympathetic outflow and blood pressure, and modulate fluid balance. However, the role of the angiotensin type-2 receptor (AT2R) in the neural control of
Autor:
Robert W, Regenhardt, Adam P, Mecca, Fiona, Desland, Phillip F, Ritucci-Chinni, Jacob A, Ludin, David, Greenstein, Cristina, Banuelos, Jennifer L, Bizon, Mary K, Reinhard, Colin, Sumners
Publikováno v:
Experimental physiology. 99(2)
What is the central question of this study? Activation of angiotensin-converting enzyme 2, resulting in production of angiotensin-(1-7) and stimulation of its receptor, Mas, exerts beneficial actions in a number cardiovascular diseases, including isc