Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jacob A. Englaender"'
Autor:
Ethan T. Hillman, Elizabeth M. Frazier, Evan K. Shank, Adrian N. Ortiz-Velez, Jacob A. Englaender, Kevin V. Solomon
Publikováno v:
Microorganisms, Vol 9, Iss 9, p 1986 (2021)
Anaerobic fungi are emerging biotechnology platforms with genomes rich in biosynthetic potential. Yet, the heterologous expression of their biosynthetic pathways has had limited success in model hosts like E. coli. We find one reason for this is that
Externí odkaz:
https://doaj.org/article/cf66c9db8e62436bbbccb77031260734
Autor:
J. Andrew Jones, Victoria R. Vernacchio, Shannon M. Collins, Abhijit N. Shirke, Yu Xiu, Jacob A. Englaender, Brady F. Cress, Catherine C. McCutcheon, Robert J. Linhardt, Richard A. Gross, Mattheos A. G. Koffas
Publikováno v:
mBio, Vol 8, Iss 3 (2017)
ABSTRACT Fermentation-based chemical production strategies provide a feasible route for the rapid, safe, and sustainable production of a wide variety of important chemical products, ranging from fuels to pharmaceuticals. These strategies have yet to
Externí odkaz:
https://doaj.org/article/e8e823118eb74a3091c85258ec13f55c
Autor:
Ian Wheeldon, Jacob A. Englaender, Ethan T. Hillman, Kevin V. Solomon, Casey A. Hooker, Mengwan Li
Publikováno v:
Biotechnology progressREFERENCES. 37(5)
Development of the bioeconomy is driven by our ability to access the energy-rich carbon trapped in recalcitrant plant materials. Current strategies to release this carbon rely on expensive enzyme cocktails and physicochemical pretreatment, producing
Autor:
Kira Bartlett, Ameer Hamza Shakeel, Jacob A. Englaender, Mark Kester, Joseph Thomas Frank, Sepehr Zomorodi, Sherif M. Sherif, Elisabeth Somers, Payam Pourtaheri, Sergio M. Carballo, Tabibul Islam, Zachery George Davis, Lisa Chen
Publikováno v:
Microbial Biotechnology
Microbial Biotechnology, Vol 14, Iss 4, Pp 1847-1856 (2021)
Microbial Biotechnology, Vol 14, Iss 4, Pp 1847-1856 (2021)
Spray‐induced gene silencing (SIGS) using topical dsRNA applications has risen as a promising, target‐specific, and environmentally‐friendly disease management strategy against phytopathogenic fungi. We demonstrated that minicell‐encapsulated
Autor:
Robert J. Linhardt, Richard A. Gross, Jacob A. Englaender, Glenn L. Butterfoss, Allison S. Zwarycz, Abhijit N. Shirke, Christine White
Publikováno v:
Biochemistry. 57:1190-1200
Cutinases are polyester hydrolases that show a remarkable capability to hydrolyze polyethylene terephthalate (PET) to its monomeric units. This revelation has stimulated research aimed at developing sustainable and green cutinase-catalyzed PET recycl
Autor:
Jacob A. Englaender, Kevin V. Solomon, Evan K. Shank, Ethan T. Hillman, Adrian N. Ortiz-Velez, Elizabeth M. Frazier
Publikováno v:
Microorganisms
Volume 9
Issue 9
Microorganisms, Vol 9, Iss 1986, p 1986 (2021)
Volume 9
Issue 9
Microorganisms, Vol 9, Iss 1986, p 1986 (2021)
Anaerobic fungi are emerging biotechnology platforms with genomes rich in biosynthetic potential. Yet, the heterologous expression of their biosynthetic pathways has had limited success in model hosts like E. coli. We find one reason for this is that
Autor:
Jacob A. Englaender, Mattheos A. G. Koffas, Brady F. Cress, Thomas E. Kuhlman, Robert J. Linhardt, J. Andrew Jones
Publikováno v:
ACS Synthetic Biology. 6:710-720
Chromosomal integration offers a selection-free alternative to DNA plasmids for expression of foreign proteins and metabolic pathways. Episomal plasmid DNA is convenient but has drawbacks including increased metabolic burden and the requirement for s
Autor:
Jacob A. Englaender, Quentin D. Leitz, Robert J. Linhardt, Shannon M. Collins, J. Andrew Jones, Brady F. Cress, Daniel C. Kim, Mattheos A. G. Koffas
Publikováno v:
Nucleic acids research, vol 44, iss 9
Nucleic Acids Research
Nucleic Acids Research
Robust gene circuit construction requires use of promoters exhibiting low crosstalk. Orthogonal promoters have been engineered utilizing an assortment of natural and synthetic transcription factors, but design of large orthogonal promoter-repressor s
Autor:
Shannon M. Collins, Victoria R. Vernacchio, Abhijit N. Shirke, J. Andrew Jones, Brady F. Cress, Yu Xiu, Richard A. Gross, Mattheos A. G. Koffas, Robert J. Linhardt, Jacob A. Englaender, Catherine C. McCutcheon
Publikováno v:
mBio, Vol 8, Iss 3, p e00621-17 (2017)
mBio, Vol 8, Iss 3 (2017)
mBio, Vol 8, Iss 3 (2017)
Fermentation-based chemical production strategies provide a feasible route for the rapid, safe, and sustainable production of a wide variety of important chemical products, ranging from fuels to pharmaceuticals. These strategies have yet to find wide
Autor:
Mattheos A. G. Koffas, Lei Lin, Fuming Zhang, Yuanyuan Zhu, Xinyue Liu, Richard A. Gross, Robert J. Linhardt, Jacob A. Englaender, Abhijit N. Shirke
Publikováno v:
Applied microbiology and biotechnology. 101(7)
Heparin, an anticoagulant drug, is biosynthesized in selected animal cells. The heparin biosynthetic enzymes mainly consist of sulfotransferases and all are integral transmembrane glycoproteins. These enzymes are generally produced in engineered Esch