Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jacob, Lueck"'
Autor:
Shuai Wu, Archit Garg, Zachary Mazanek, Gretchen Belotte, Jeffery J Zhou, Christina M Stallings, Jacob Lueck, Aubrey Roland, Michael A Chattergoon, Jungsan Sohn
Publikováno v:
eLife, Vol 13 (2024)
Inflammasomes are filamentous signaling platforms essential for host defense against various intracellular calamities such as pathogen invasion and genotoxic stresses. However, dysregulated inflammasomes cause an array of human diseases including aut
Externí odkaz:
https://doaj.org/article/7d9bf18aaa8f48739b5717b8995d9018
Autor:
Mariusz Matyszewski, Weili Zheng, Jacob Lueck, Zachary Mazanek, Naveen Mohideen, Albert Y. Lau, Edward H. Egelman, Jungsan Sohn
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
AIM2-ASC inflammasomes are filamentous signalling platforms that play a central role in host innate defence. Here, the authors present the filament cryo-EM structure of the inflammasome receptor AIM2, which is very similar to the adaptor ASC filament
Externí odkaz:
https://doaj.org/article/e9f87d25b7154a22a54ca96eb6816da0
Autor:
Zachary Mazanek, Shuai Wu, Gretchen Belotte, Jeffery J. Zhou, Christina M. Stallings, Archit Garg, Jacob Lueck, Jungsan Sohn
Inflammasomes are filamentous signaling platforms essential for host defense against various intracellular calamities such as pathogen invasion and genotoxic stresses. However, dysregulated inflammasomes cause an array of human diseases including aut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c8f4125023043cbd030086505b0c37e
https://doi.org/10.1101/2022.08.02.502519
https://doi.org/10.1101/2022.08.02.502519
Autor:
Jungsan Sohn, Weili Zheng, Mariusz Matyszewski, Zachary Mazanek, Albert Y. Lau, Edward H. Egelman, Naveen Mohideen, Jacob Lueck
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Inflammasomes are filamentous signaling platforms integral to innate immunity. Currently, little is known about how these structurally similar filaments recognize and distinguish one another. A cryo-EM structure of the AIM2PYD filament reveals that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f09a1f6f61216863698bbbc1814f6c1
https://pubmed.ncbi.nlm.nih.gov/33980849
https://pubmed.ncbi.nlm.nih.gov/33980849
Autor:
Jungsan Sohn, Weili Zheng, Jacob Lueck, Mariusz Matyszewski, Edward H. Egelman, Brendan Antiochos
Publikováno v:
Journal of Biological Chemistry. 293:20240-20248
Inflammasomes are supramolecular signaling platforms integral to innate immune defense against invading pathogens. The NOD-like receptor (NLR) family apoptosis inhibitory protein (NAIP)·NLR family caspase-recruiting domain (CARD) domain-containing 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40d70202fdae204bc3849fcd99024043
https://doi.org/10.1074/jbc.ra118.006050
https://doi.org/10.1074/jbc.ra118.006050
Autor:
Mariusz, Matyszewski, Weili, Zheng, Jacob, Lueck, Brendan, Antiochos, Edward H, Egelman, Jungsan, Sohn
Publikováno v:
The Journal of biological chemistry. 293(52)
Inflammasomes are supramolecular signaling platforms integral to innate immune defense against invading pathogens. The NOD-like receptor (NLR) family apoptosis inhibitory protein (NAIP)·NLR family caspase-recruiting domain (CARD) domain-containing 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5786062af13386a723b42db71dabaacf
https://pubmed.ncbi.nlm.nih.gov/30385506
https://pubmed.ncbi.nlm.nih.gov/30385506