Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Jacob, Goodwin"'
Publikováno v:
AACE Clinical Case Reports, Vol 6, Iss 4, Pp e179-e182 (2020)
ABSTRACT: Objective: Sweet syndrome (SS) is characterized by an inflammatory rash that has been associated with a number of drugs and malignant, inflammatory, and infectious conditions. Rare accounts of Hashimoto thyroiditis (HT) presenting with SS e
Externí odkaz:
https://doaj.org/article/47cb4af97f754362a37e063972eaef2a
Publikováno v:
Stem Cell Research, Vol 26, Iss , Pp 36-43 (2018)
Characterisation of mouse pluripotent stem cells has revealed two distinct pluripotent states, naive and primed, that maintain characteristics of the pre and post implanted epiblast respectively. Recent studies have developed several culture systems
Externí odkaz:
https://doaj.org/article/3ff45556e5314a69ab33c145f24c5f05
Publikováno v:
Biomolecules, Vol 4, Iss 3, Pp 795-811 (2014)
In Parkinson’s disease and some atypical Parkinson’s syndromes, aggregation of the α-synuclein protein (α-syn) has been linked to neurodegeneration. Many triggers for pathological α-syn aggregation have been identified, including port-translat
Externí odkaz:
https://doaj.org/article/e4bfa11578bc4cf6b8ca728ae46ff0d0
Autor:
Elham Alizadeh Pasdar, Michael Smits, Michael Stapelberg, Martina Bajzikova, Marina Stantic, Jacob Goodwin, Bing Yan, Jan Stursa, Jaromira Kovarova, Karishma Sachaphibulkij, Ayenachew Bezawork-Geleta, Margaryta Sobol, Anatoly Filimonenko, Marco Tomasetti, Renata Zobalova, Pavel Hozak, Lan-Feng Dong, Jiri Neuzil
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156012 (2016)
[This corrects the article DOI: 10.1371/journal.pone.0119549.].
Externí odkaz:
https://doaj.org/article/a8bf72d4bf63430498757f9ffef1f6e6
Autor:
Elham Alizadeh Pasdar, Michael Smits, Michael Stapelberg, Martina Bajzikova, Marina Stantic, Jacob Goodwin, Bing Yan, Jan Stursa, Jaromira Kovarova, Karishma Sachaphibulkij, Ayenachew Bezawork-Geleta, Margaryta Sobol, Anatoly Filimonenko, Marco Tomasetti, Renata Zobalova, Pavel Hozak, Lan-Feng Dong, Jiri Neuzil
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0119549 (2015)
Malignant mesothelioma (MM) is an aggressive type of tumour causing high mortality. One reason for this paradigm may be the existence of a subpopulation of tumour-initiating cells (TICs) that endow MM with drug resistance and recurrence. The objectiv
Externí odkaz:
https://doaj.org/article/a785e430df50486c96bc071f5315b30c
Publikováno v:
AACE Clinical Case Reports, Vol 6, Iss 4, Pp e179-e182 (2020)
AACE Clin Case Rep
AACE Clin Case Rep
Objective: Sweet syndrome (SS) is characterized by an inflammatory rash that has been associated with a number of drugs and malignant, inflammatory, and infectious conditions. Rare accounts of Hashimoto thyroiditis (HT) presenting with SS exist in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a12388007156e2fe5de1266857dde92e
http://www.sciencedirect.com/science/article/pii/S2376060520300067
http://www.sciencedirect.com/science/article/pii/S2376060520300067
Publikováno v:
Biochimica et biophysica acta. Reviews on cancer. 1875(1)
For a drug candidate to be fully developed takes years and investment of hundreds of millions of dollars. There is no doubt that drug development is difficult and risky, but vital to protecting against devastating disease. This difficulty is clearly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca6165b301aecc8e5e595c883ffefa2c
https://pubmed.ncbi.nlm.nih.gov/33129865
https://pubmed.ncbi.nlm.nih.gov/33129865
Autor:
Marco Tomasetti, Linda Nocchi, Jiri Neuzil, Jacob Goodwin, Maria Nguyen, Lanfeng Dong, Nicola Manzella, Sara Staffolani, Claudio Milanese, Beatrice Garrone, Renata Alleva, Battista Borghi, Lory Santarelli, Roberto Guerrieri
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52263 (2012)
BackgroundThe redox-silent vitamin E analog α-tocopheryl succinate (α-TOS) was found to synergistically cooperate with vitamin K3 (VK3) plus ascorbic acid (AA) in the induction of cancer cell-selective apoptosis via a caspase-independent pathway. H
Externí odkaz:
https://doaj.org/article/a4582d3a4c6c4292a996162359869d53
Autor:
Berwini Endaya, Jiri Neuzil, Jiri Cerny, Renata Zobalova, Pavel Hozák, Bing Yan, Tomáš Špaček, Petr Jezek, Karishma Sachaphibulkij, Jakub Rohlena, Jan Blecha, Katerina Rohlenova, Lan-Feng Dong, Margaryta Sobol, Lukas Werner, Jacob Goodwin, Magdalena Vondrusova, Elham Alizadeh Pesdar, Maria Nga Nguyen, Jan Stursa, Ayenachew Bezawork-Geleta, Jaroslav Truksa
Publikováno v:
Antioxidants & Redox Signaling. 26:84-103
Aims: Expression of the HER2 oncogene in breast cancer is associated with resistance to treatment, and Her2 may regulate bioenergetics. Therefore, we investigated whether disruption of the electron transport chain (ETC) is a viable strategy to elimin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53e2daaac3c4cca08da325ce09bf1eba
https://doi.org/10.1089/ars.2016.6677
https://doi.org/10.1089/ars.2016.6677
Autor:
Lars-Gunnar Larsson, Jiri Bartek, Madhurendra Singh, Alina Castell, Galina Selivanova, Siti Mariam Zakaria, Susanna Tronnersjö, Fan Zhang, Jacob Goodwin, Vedrana Tabor
Publikováno v:
Cell Cycle
The MYC and RAS oncogenes are sufficient for transformation of normal rodent cells. This cooperativity is at least in part based on suppression of RAS-induced cellular senescence by MYC and block of MYC-induced apoptosis by RAS – thereby canceling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042c4161ceb4b957bdef3ca5a160b230
https://pubmed.ncbi.nlm.nih.gov/30526305
https://pubmed.ncbi.nlm.nih.gov/30526305