Zobrazeno 1 - 10
of 199
pro vyhledávání: '"Jacob, Beal"'
Autor:
Iain George, Paul Ross, Yixian Yang, Martin Holub, Nina Rajpurohit, Ibrahim Aldulijan, Jacob Beal, Alejandro Vignoni, Dennis Mishler
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Synthetic biology is an interdisciplinary field that brings together engineering and biology concepts alongside the arts and social sciences to develop solutions to pressing problems in our world. The education of students entering this field has rel
Externí odkaz:
https://doaj.org/article/746138ea44aa45dd9fcb30e13e53aa5e
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-6 (2023)
Abstract As synthetic biology becomes increasingly capable and accessible, it is likewise increasingly critical to be able to make accurate biosecurity determinations regarding the pathogenicity or toxicity of particular nucleic acid or amino acid se
Externí odkaz:
https://doaj.org/article/a6a45a2c80124d63b21966c7389b2522
Autor:
Katherine A. Kiwimagi, Justin H. Letendre, Benjamin H. Weinberg, Junmin Wang, Mingzhe Chen, Leandro Watanabe, Chris J. Myers, Jacob Beal, Wilson W. Wong, Ron Weiss
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Kiwimagi & Letendre et al. present a workflow to quantitatively define recombinase-based digitizer and predict responses to different input signals. With a mechanistic/phenotypic model that can predict circuit performance, they generate a synthetic c
Externí odkaz:
https://doaj.org/article/d4030bb1a2c34df186adb664ad87a908
Autor:
Jacob Beal, Miles Rogers
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 12, Pp 1-5 (2020)
Graphical Abstract Engineering biological organisms is a complex process and challenging that could benefit from a combination of standardization and automation. This Commentary discusses the advantages and challenges of achieving high levels of auto
Externí odkaz:
https://doaj.org/article/8f656feb4a51458e9289d4d75fc74ea6
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Genome-scale engineering requires the integration of a wide range of in silico and in vivo technologies, as well data management procedures and legal infrastructure. Here the authors provide a list of recommendations to address these challenges.
Externí odkaz:
https://doaj.org/article/6e2b00be562f422f97310610f3d902b6
Autor:
Benjamin H. Weinberg, Jang Hwan Cho, Yash Agarwal, N. T. Hang Pham, Leidy D. Caraballo, Maciej Walkosz, Charina Ortega, Micaela Trexler, Nathan Tague, Billy Law, William K. J. Benman, Justin Letendre, Jacob Beal, Wilson W. Wong
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
The availability of high performance recombinases with low basal activity and high dynamic range is limited. Here the authors present a library of over 20 orthogonal split recombinases that can be induced by small molecules, light and temperature in
Externí odkaz:
https://doaj.org/article/2d4222928cd84b6aa52fbca43ee615fa
Autor:
Jacob Beal, Geoff S Baldwin, Natalie G Farny, Markus Gershater, Traci Haddock-Angelli, Russell Buckley-Taylor, Ari Dwijayanti, Daisuke Kiga, Meagan Lizarazo, John Marken, Kim de Mora, Randy Rettberg, Vishal Sanchania, Vinoo Selvarajah, Abigail Sison, Marko Storch, Christopher T Workman, iGEM Interlab Study Contributors
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0252263 (2021)
Reproducibility is a key challenge of synthetic biology, but the foundation of reproducibility is only as solid as the reference materials it is built upon. Here we focus on the reproducibility of fluorescence measurements from bacteria transformed w
Externí odkaz:
https://doaj.org/article/c7ded86e73e9474f93a3c887a1d5cc76
Publikováno v:
IEEE Transactions on Automatic Control. 68:454-461
Spreading information through a network of devices is a core activity for most distributed systems. As such, self-stabilizing algorithms implementing information spreading are one of the key building blocks enabling aggregate computing to provide res
Autor:
Peter Lamb, Seema Kantak, Bryan Glaser, Justin Wetter, Bee-Cheng Sim, Jeff Higaki, Jacob Beal, Sara Ollerman, Dileep Pulukkunat, Mandar Bawadekar, Charles Kaplan, Bonnie Hammer
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/1667f5e92ad147a390c033bc9d07eb14
Publikováno v:
Logical Methods in Computer Science, Vol Volume 16, Issue 4 (2020)
Field-based coordination has been proposed as a model for coordinating collective adaptive systems, promoting a view of distributed computations as functions manipulating data structures spread over space and evolving over time, called computational
Externí odkaz:
https://doaj.org/article/4dafde12f1464d97979404cc24f1c811