Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Jaco, van der Torre"'
Autor:
Zeliha Yalçin, Shiu Yeung Lam, Marieke H. Peuscher, Jaco van der Torre, Sha Zhu, Prasanna V. Iyengar, Daniel Salas-Lloret, Inge de Krijger, Nathalie Moatti, Ruben van der Lugt, Mattia Falcone, Aurora Cerutti, Onno B. Bleijerveld, Liesbeth Hoekman, Román González-Prieto, Jacqueline J. L. Jacobs
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Maintenance of genome integrity requires tight control of DNA damage response (DDR) signalling and repair, with phosphorylation and ubiquitination representing key elements. How these events are coordinated to achieve productive DNA repair r
Externí odkaz:
https://doaj.org/article/5904fb9cf15e4ea0bcf5f618e256368f
Autor:
Roman Barth, Biswajit Pradhan, Eugene Kim, Iain F. Davidson, Jaco van der Torre, Jan-Michael Peters, Cees Dekker
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract DNA loop extrusion by structural-maintenance-of-chromosome (SMC) complexes has emerged as a primary organizing principle for chromosomes. The mechanism by which SMC motor proteins extrude DNA loops is still unresolved and much debated. The r
Externí odkaz:
https://doaj.org/article/12547bab05c54d948ad59bec6503ca6b
Autor:
Roman Barth, Biswajit Pradhan, Eugene Kim, Iain F. Davidson, Jaco van der Torre, Jan‑Michael Peters, Cees Dekker
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/c173b80b0c254e0184a119d15c898acc
Autor:
Philip Ketterer, Adithya N. Ananth, Diederik S. Laman Trip, Ankur Mishra, Eva Bertosin, Mahipal Ganji, Jaco van der Torre, Patrick Onck, Hendrik Dietz, Cees Dekker
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
FG-Nups are disordered proteins in the nuclear pore complex (NPC) where they selectively control nuclear transport. Here authors build NPC-mimics based on DNA origami rings which attach a certain numbers of Nups to analyse those nanopores by cryoEM a
Externí odkaz:
https://doaj.org/article/3c16edd0fd33457389226bffa28bd552
Autor:
Michel Bengtson, Mitasha Bharadwaj, Oskar Franch, Jaco van der Torre, Veronique Meerdink, Henk Schallig, Cees Dekker
Publikováno v:
Nanoscale, 14(5)
Nanoscale, 14(5), 1885-1895. Royal Society of Chemistry
Nanoscale 14
Nanoscale, 14(5), 1885-1895. Royal Society of Chemistry
Nanoscale 14
Nucleic-acid detection is crucial for basic research as well as for applications in medicine such as diagnostics. In resource-limited settings, however, most DNA-detection diagnostic schemes are inapplicable since they rely on expensive machinery, el
Autor:
Iain F. Davidson, Roman Barth, Maciej Zaczek, Jaco van der Torre, Wen Tang, Kota Nagasaka, Richard Janissen, Jacob Kerssemakers, Gordana Wutz, Cees Dekker, Jan-Michael Peters
Publikováno v:
Nature: international weekly journal of science, 616(7958)
In eukaryotes, genomic DNA is extruded into loops by cohesin1. By restraining this process, the DNA-binding protein CCCTC-binding factor (CTCF) generates topologically associating domains (TADs)2,3 that have important roles in gene regulation and rec
Autor:
Sung Hyun Kim, Mahipal Ganji, Eugene Kim, Jaco van der Torre, Elio Abbondanzieri, Cees Dekker
Publikováno v:
eLife, Vol 7 (2018)
The three-dimensional organization of DNA is increasingly understood to play a decisive role in vital cellular processes. Many studies focus on the role of DNA-packaging proteins, crowding, and confinement in arranging chromatin, but structural infor
Externí odkaz:
https://doaj.org/article/dfb615d3e2d54b08900e241d48082528
Autor:
Biswajit Pradhan, Roman Barth, Eugene Kim, Iain F. Davidson, Jaco van der Torre, Jan-Michael Peters, Cees Dekker
SUMMARYDNA loop extrusion by structural-maintenance-of-chromosome (SMC) complexes has emerged as a primary organizing principle for chromosomes. The mechanism by which SMC motor proteins extrude DNA loops is still unresolved and much debated. The rin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::061068e889aee2a6d3b7785d69273962
https://doi.org/10.1101/2022.08.02.502451
https://doi.org/10.1101/2022.08.02.502451
Autor:
Martin, Holub, Anthony, Birnie, Aleksandre, Japaridze, Jaco, van der Torre, Maxime den, Ridder, Carol, de Ram, Martin, Pabst, Cees, Dekker
Publikováno v:
Cell reports methods. 2(12)
Chromosome structure and function is studied using various cell-based methods as well as with a range of
Autor:
Martin Holub, Anthony Birnie, Aleksandre Japaridze, Jaco van der Torre, Maxime den Ridder, Carol de Ram, Martin Pabst, Cees Dekker
Chromosome structure and function is studied in cells using imaging and chromosome-conformation-based methods as well as in vitro with a range of single-molecule techniques. Here we present a method to obtain genome-size (megabasepair length) deprote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a9916287a290117fc447b812c14ba69
https://doi.org/10.1101/2022.06.22.497140
https://doi.org/10.1101/2022.06.22.497140