Antiseizure potential of the ancient Greek medicinal plant Helleborus odorus subsp. cyclophyllus and identification of its main active principles

Autor: Brillatz, Théo, Jacmin, Maxime, Vougogiannopoulou, Konstantina, Petrakis, Eleftherios A., Kalpoutzakis, Eleftherios, Houriet, Joëlle, Pellissier, Léonie, Rutz, Adriano, Marcourt, Laurence, Queiroz, Emerson Ferreira, Crawford, Alexander D., Skaltsounis, Alexios-Leandros, Wolfender, Jean-Luc

Publikováno v: In Journal of Ethnopharmacology 15 September 2020 259

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CHD2 variants are a risk factor for photosensitivity in epilepsy

Autor: Galizia, Elizabeth C, Myers, Candace T, Leu, Costin, de Kovel, Carolien G F, Afrikanova, Tatiana, Cordero-Maldonado, Maria Lorena, Martins, Teresa G, Jacmin, Maxime, Drury, Suzanne, Krishna Chinthapalli, V, Muhle, Hiltrud, Pendziwiat, Manuela, Sander, Thomas, Ruppert, Ann-Kathrin, Møller, Rikke S, Thiele, Holger, Krause, Roland, Schubert, Julian, Lehesjoki, Anna-Elina, Nürnberg, Peter, Lerche, Holger, Palotie, Aarno, Coppola, Antonietta, Striano, Salvatore, Gaudio, Luigi Del, Boustred, Christopher, Schneider, Amy L, Lench, Nicholas, Jocic-Jakubi, Bosanka, Covanis, Athanasios, Capovilla, Giuseppe, Veggiotti, Pierangelo, Piccioli, Marta, Parisi, Pasquale, Cantonetti, Laura, Sadleir, Lynette G, Mullen, Saul A, Berkovic, Samuel F, Stephani, Ulrich, Helbig, Ingo, Crawford, Alexander D, Esguerra, Zara, Federico, Striano, Pasquale, Camila, V, Kasteleijn-Nolst Trenité, Dorothee G A, Koeleman, Bobby P C, Mefford, Heather C, Scheffer, Ingrid E, Sisodiya, Sanjay M

Publikováno v: Brain
Galizia, E C, Myers, C T, Leu, C, de Kovel, C G F, Afrikanova, T, Cordero-Maldonado, M L, Martins, T G, Jacmin, M, Drury, S, Krishna Chinthapalli, V, Muhle, H, Pendziwiat, M, Sander, T, Ruppert, A-K, Møller, R S, Thiele, H, Krause, R, Schubert, J, Lehesjoki, A-E, Nürnberg, P, Lerche, H, Palotie, A, Coppola, A, Striano, S, Gaudio, L D, Boustred, C, Schneider, A L, Lench, N, Jocic-Jakubi, B, Covanis, A, Capovilla, G, Veggiotti, P, Piccioli, M, Parisi, P, Cantonetti, L, Sadleir, L G, Mullen, S A, Berkovic, S F, Stephani, U, Helbig, I, Crawford, A D, Esguerra, C V, Kasteleijn-Nolst Trenité, D G A, Koeleman, B P C, Mefford, H C, Scheffer, I E, Sisodiya, S M & EuroEPINOMICS CoGIE Consortium 2015, ' CHD2 variants are a risk factor for photosensitivity in epilepsy ', Brain, vol. 138, no. 5, pp. 1198-1208 . https://doi.org/10.1093/brain/awv052
Scopus-Elsevier
Brain, 138, 1198. Oxford University Press

Photosensitivity in epilepsy is common and has high heritability, but its genetic basis remains uncertain. Galizia et al. reveal an overrepresentation of unique variants of CHD2 — which encodes the transcriptional regulator ‘chromodomain helicase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fcb236cd2f91be37e81fb911a4fd3e68
http://europepmc.org/articles/PMC4407192

Zebrafish-based identification of the antiseizure nucleoside inosine from the marine diatom Skeletonema marinoi.

Autor: Brillatz T; School of Pharmaceutical Sciences, EPGL, University of Geneva, University of Lausanne, Genève, Switzerland., Lauritano C; Integrative Marine Ecology Department, Stazione Zoologica Anton Dohrn, Napoli, Italy., Jacmin M; Luxembourg Centre for Systems Biomedicine, Université du Luxembourg, Belvaux, Luxembourg.; Theracule S.á r.l., Belval, Luxembourg., Khamma S; School of Pharmaceutical Sciences, EPGL, University of Geneva, University of Lausanne, Genève, Switzerland., Marcourt L; School of Pharmaceutical Sciences, EPGL, University of Geneva, University of Lausanne, Genève, Switzerland., Righi D; School of Pharmaceutical Sciences, EPGL, University of Geneva, University of Lausanne, Genève, Switzerland., Romano G; Integrative Marine Ecology Department, Stazione Zoologica Anton Dohrn, Napoli, Italy., Esposito F; Integrative Marine Ecology Department, Stazione Zoologica Anton Dohrn, Napoli, Italy., Ianora A; Integrative Marine Ecology Department, Stazione Zoologica Anton Dohrn, Napoli, Italy., Queiroz EF; School of Pharmaceutical Sciences, EPGL, University of Geneva, University of Lausanne, Genève, Switzerland., Wolfender JL; School of Pharmaceutical Sciences, EPGL, University of Geneva, University of Lausanne, Genève, Switzerland., Crawford AD; Luxembourg Centre for Systems Biomedicine, Université du Luxembourg, Belvaux, Luxembourg.; Theracule S.á r.l., Belval, Luxembourg.; Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Oslo, Norway.

Publikováno v: PloS one [PLoS One] 2018 Apr 24; Vol. 13 (4), pp. e0196195. Date of Electronic Publication: 2018 Apr 24 (Print Publication: 2018).