Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jaclyn Y. Lock"'
Autor:
Jaclyn Y. Lock, Mariaelena Caboni, Philip Strandwitz, Madeleine Morrissette, Kevin DiBona, Brian A. Joughin, Kim Lewis, Rebecca L. Carrier
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Considerable effort has been put forth to understand mechanisms by which the microbiota modulates and responds to inflammation. Here, we explored whether oxidation metabolites produced by the host during inflammation, sodium nitrate and trimethylamin
Externí odkaz:
https://doaj.org/article/9e96cdbf33444485a4bae94618b77ab4
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209151 (2018)
Mucus constitutes a protective layer which coats the gastrointestinal tract, controlling interactions of both commensal and pathogenic microbes with underlying tissues. Changes to the mucus barrier, for example due to altered mucin expression or exte
Externí odkaz:
https://doaj.org/article/12055556609b4797b5bca29e558c3456
Autor:
Jaclyn Y, Lock, Mariaelena, Caboni, Philip, Strandwitz, Madeleine, Morrissette, Kevin, DiBona, Brian A, Joughin, Kim, Lewis, Rebecca L, Carrier
Publikováno v:
Gut microbes. 14(1)
Considerable effort has been put forth to understand mechanisms by which the microbiota modulates and responds to inflammation. Here, we explored whether oxidation metabolites produced by the host during inflammation, sodium nitrate and trimethylamin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8c026bf1dee0f288f095efdd7e5df093
https://pubmed.ncbi.nlm.nih.gov/35316142
https://pubmed.ncbi.nlm.nih.gov/35316142
Autor:
Emily C. Freund, Timurs Maculins, Aditya Murthy, Benjamin Haley, Jaclyn Y. Lock, Christopher J. Bohlen, Lélia Delamarre, Jaehak Oh
Publikováno v:
The Journal of Experimental Medicine
Highly efficient gene editing in primary myeloid cells is made possible by optimized non-viral delivery of CRISPR-Cas9. This enables single and multiplexed gene knockout in monocytes, macrophages, and dendritic cells to advance innate immunity resear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f93a692bc6ff3c495be2111379da057
http://europepmc.org/articles/PMC7336301
http://europepmc.org/articles/PMC7336301
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Necrotizing enterocolitis (NEC) is a devastating gastrointestinal disease of incompletely understood pathophysiology predominantly affecting premature infants. While NEC is associated with microbial invasion of intestinal tissues, and mucus modulates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6b51d971f64e790a9f73fe06bd23535
https://doi.org/10.1038/s41598-020-63593-5
https://doi.org/10.1038/s41598-020-63593-5
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
The consumption of generally regarded as safe emulsifiers has increased, and has been associated with an increased prevalence of inflammatory bowel and metabolic diseases, as well as an altered microbiome. The mucus barrier, which selectively control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f49ff55983b86a5703bc73e31138715
https://doi.org/10.1038/s41598-018-27957-2
https://doi.org/10.1038/s41598-018-27957-2
Autor:
David I. Walsh, E. Victoria Dydek, Jaclyn Y. Lock, Taylor L. Carlson, Rebecca L. Carrier, David S. Kong, Catherine R. Cabrera, Todd Thorsen
Publikováno v:
SLAS technology. 23(2)
Gut-on-a-chip in vitro modeling is an emerging field, as the human gut epithelium and gut microbiome have been recently identified as novel drug targets for a wide variety of diseases. Realistic in vitro gut models require a variety of precise enviro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eb46dac6c3d6e42a11f5fb950add580
https://pubmed.ncbi.nlm.nih.gov/29186668
https://pubmed.ncbi.nlm.nih.gov/29186668
Mucus is a complex hydrogel that acts as a natural barrier to drug delivery at different mucosal surfaces including the respiratory, gastrointestinal, and vaginal tracts. To elucidate the role mucus plays in drug delivery, different in vitro, in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f72a0cb286f400a9b9033822a8d5ae
https://europepmc.org/articles/PMC6463479/
https://europepmc.org/articles/PMC6463479/
Publikováno v:
Materials Science Forum. :413-418
Magnesium-based alloys are promising for various biomedical applications due to their advantageous mechanical and biological properties. In this study, we investigated the potential use of magnesium-based alloys for urological device applications, e.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0495b33bedd624f5a96dd65ed230c345
https://doi.org/10.4028/www.scientific.net/msf.783-786.413
https://doi.org/10.4028/www.scientific.net/msf.783-786.413
Autor:
Vicente Nuñez, Valentine I. Vullev, Jaclyn Y. Lock, Srigokul Upadhyayula, Huinan Liu, Andrew Whall, Eric Wyatt
Publikováno v:
Journal of Biomedical Materials Research Part A. 102:781-792
This article presents an investigation on the effectiveness of magnesium and its alloys as a novel class of antibacterial and biodegradable materials for ureteral stent applications. Magnesium is a lightweight and biodegradable metallic material with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf3722c6797d03c5e3577af15819644c
https://doi.org/10.1002/jbm.a.34741
https://doi.org/10.1002/jbm.a.34741