Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jaclyn S. Higgins"'
Autor:
Lily E. Adams, Sarah R. Leist, Kenneth H. Dinnon, III, Ande West, Kendra L. Gully, Elizabeth J. Anderson, Jennifer F. Loome, Emily A. Madden, John M. Powers, Alexandra Schäfer, Sanjay Sarkar, Izabella N. Castillo, Jenny S. Maron, Ryan P. McNamara, Harry L. Bertera, Mark R. Zweigert, Jaclyn S. Higgins, Brea K. Hampton, Lakshmanane Premkumar, Galit Alter, Stephanie A. Montgomery, Victoria K. Baxter, Mark T. Heise, Ralph S. Baric
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112326- (2023)
Summary: Group 2B β-coronaviruses (sarbecoviruses) have caused regional and global epidemics in modern history. Here, we evaluate the mechanisms of cross-sarbecovirus protective immunity, currently less clear yet important for pan-sarbecovirus vacci
Externí odkaz:
https://doaj.org/article/7da7f2fa9eee4314bfa59cc3b0f22f10
Autor:
Camille N Pierre, Lily E Adams, Jaclyn S Higgins, Kara Anasti, Derrick Goodman, Dieter Mielke, Sherry Stanfield-Oakley, John M Powers, Dapeng Li, Wes Rountree, Yunfei Wang, Robert J Edwards, S Munir Alam, Guido Ferrari, Georgia D Tomaras, Barton F Haynes, Ralph S Baric, Kevin O Saunders
Publikováno v:
PLoS Pathogens, Vol 20, Iss 6, p e1011569 (2024)
Antibodies perform both neutralizing and non-neutralizing effector functions that protect against certain pathogen-induced diseases. A human antibody directed at the SARS-CoV-2 Spike N-terminal domain (NTD), DH1052, was recently shown to be non-neutr
Externí odkaz:
https://doaj.org/article/d7d7ba6a7f484717a5dd976d5cd05be0
Autor:
Taronna R. Maines, C. Garrett Rappazzo, Gary R. Whittaker, Hannah C. Watkins, Annie Chau, Jaclyn S. Higgins, Cynthia A. Leifer, Nicole Brock, Michael R. King, David Putnam, Matthew P. DeLisa, Joseph P.B. Cannizzo, Aditya Misra, Xiangjie Sun
Recombinant, Escherichia coli-derived outer membrane vesicles (rOMVs), which display heterologous protein subunits, have potential as a vaccine adjuvant platform. One drawback to rOMVs is their lipopolysaccharide (LPS) content, limiting their transla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5359815b0779c5b0ecf9daaa74c106fc
https://europepmc.org/articles/PMC5383554/
https://europepmc.org/articles/PMC5383554/
Publikováno v:
Scientific Reports
The biodistribution of biodegradable nanoparticles can be difficult to quantify. We report a method using time resolved fluorescence (TRF) from a lanthanide chelate to minimize background autofluorescence and maximize the signal to noise ratio to det