Zobrazeno 1 - 10
of 1 004
pro vyhledávání: '"Jaclyn S."'
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-22 (2024)
Abstract Suicide is a leading cause of death among adolescents, and recent suicide theories have sought to clarify the factors that facilitate the transition from suicide ideation to action. Specifically, the Interpersonal Theory of Suicide (IPTS), I
Externí odkaz:
https://doaj.org/article/587cfda8bebb4fd2a182e5b09620a49d
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Animal models of depression show that acute stress negatively impacts functioning in neural regions sensitive to reward and punishment, often manifesting as anhedonic behaviors. However, few human studies have probed stress-induced neural ac
Externí odkaz:
https://doaj.org/article/aa9e6ee7367f4d5197cc04b98521e583
Autor:
Paul A. Bloom, David Pagliaccio, Jiahe Zhang, Clemens C. C. Bauer, Mia Kyler, Keara D. Greene, Isaac Treves, Francesca Morfini, Katherine Durham, Rachel Cherner, Zia Bajwa, Emma Wool, Valur Olafsson, Ray F. Lee, Fred Bidmead, Jonathan Cardona, Jaclyn S. Kirshenbaum, Satrajit Ghosh, Oliver Hinds, Paul Wighton, Hanga Galfalvy, H. Blair Simpson, Susan Whitfield-Gabrieli, Randy P. Auerbach
Publikováno v:
BMC Psychiatry, Vol 23, Iss 1, Pp 1-18 (2023)
Abstract Background Adolescence is characterized by a heightened vulnerability for Major Depressive Disorder (MDD) onset, and currently, treatments are only effective for roughly half of adolescents with MDD. Accordingly, novel interventions are urge
Externí odkaz:
https://doaj.org/article/790f8f3fdac240dda7e6217466ee67b6
Autor:
Sarah E. Garnish, Katherine R. Martin, Maria Kauppi, Victoria E. Jackson, Rebecca Ambrose, Vik Ven Eng, Shene Chiou, Yanxiang Meng, Daniel Frank, Emma C. Tovey Crutchfield, Komal M. Patel, Annette V. Jacobsen, Georgia K. Atkin-Smith, Ladina Di Rago, Marcel Doerflinger, Christopher R. Horne, Cathrine Hall, Samuel N. Young, Matthew Cook, Vicki Athanasopoulos, Carola G. Vinuesa, Kate E. Lawlor, Ian P. Wicks, Gregor Ebert, Ashley P. Ng, Charlotte A. Slade, Jaclyn S. Pearson, André L. Samson, John Silke, James M. Murphy, Joanne M. Hildebrand
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Across the globe, 2-3% of humans carry the p.Ser132Pro single nucleotide polymorphism in MLKL, the terminal effector protein of the inflammatory form of programmed cell death, necroptosis. Here we show that this substitution confers a gain i
Externí odkaz:
https://doaj.org/article/14198b0aa4ad4e93a3c3095f5a9f9cb4
Autor:
Elżbieta Kania, Jaclyn S. Long, David G. McEwan, Kirsten Welkenhuyzen, Rita La Rovere, Tomas Luyten, John Halpin, Evy Lobbestael, Veerle Baekelandt, Geert Bultynck, Kevin M. Ryan, Jan B. Parys
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-14 (2023)
Abstract Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are the most common genetic cause of Parkinson’s disease (PD), with growing importance also for Crohn’s disease and cancer. LRRK2 is a large and complex protein possessing both G
Externí odkaz:
https://doaj.org/article/ac990b44ebe440e7985118a7bf10125c
Autor:
Jaclyn S. Piatak, Joanne G. Carman
Publikováno v:
Journal of Public and Nonprofit Affairs, Vol 9, Iss 3 (2023)
Volunteers play a vital role in nonprofit organizations. While considerable research examines volunteer recruitment and volunteer management, less is known about how to manage volunteers in such a way that inspires volunteers to continue to volunteer
Externí odkaz:
https://doaj.org/article/785786b0d641410b8cb905ead8fc961d
Autor:
Lily E. Adams, Sarah R. Leist, Kenneth H. Dinnon, III, Ande West, Kendra L. Gully, Elizabeth J. Anderson, Jennifer F. Loome, Emily A. Madden, John M. Powers, Alexandra Schäfer, Sanjay Sarkar, Izabella N. Castillo, Jenny S. Maron, Ryan P. McNamara, Harry L. Bertera, Mark R. Zweigert, Jaclyn S. Higgins, Brea K. Hampton, Lakshmanane Premkumar, Galit Alter, Stephanie A. Montgomery, Victoria K. Baxter, Mark T. Heise, Ralph S. Baric
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112326- (2023)
Summary: Group 2B β-coronaviruses (sarbecoviruses) have caused regional and global epidemics in modern history. Here, we evaluate the mechanisms of cross-sarbecovirus protective immunity, currently less clear yet important for pan-sarbecovirus vacci
Externí odkaz:
https://doaj.org/article/7da7f2fa9eee4314bfa59cc3b0f22f10
Autor:
Patricia Coughenour, Jaclyn S. Sadicario, Nicole Karjane, Anna Beth Parlier-Ahmad, Lisa Phipps, Dace S. Svikis
Publikováno v:
Women's Health Reports, Vol 2, Iss 1, Pp 452-458 (2021)
Background: As more US states legalize cannabis use, prevalence of use continues to rise and attitudes toward use are changing. This study examined (1) the relationship between cannabis use and social acceptability of use and (2) how social acceptabi
Externí odkaz:
https://doaj.org/article/9a65aebcca04432c9af06b8ef9d44ade
Autor:
Danielle J. Ingle, Rebecca L. Ambrose, Sarah L. Baines, Sebastian Duchene, Anders Gonçalves da Silva, Darren Y. J. Lee, Miriam Jones, Mary Valcanis, George Taiaroa, Susan A. Ballard, Martyn D. Kirk, Benjamin P. Howden, Jaclyn S. Pearson, Deborah A. Williamson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Salmonella enterica serovar 4,[5],12:i:- (Salmonella 4,[5],12:i:-) is a major pathogen of humans and animals with a reported incidence in Australia three times higher than the UK and USA. Here, the authors report the circulation, antimicrobial resist
Externí odkaz:
https://doaj.org/article/a7f3158f38384007892bc435aa8a9524
Autor:
Daniel Frank, Sarah E. Garnish, Jarrod J. Sandow, Ashley Weir, Lin Liu, Elise Clayer, Lizeth Meza, Maryam Rashidi, Simon A. Cobbold, Simon R. Scutts, Marcel Doerflinger, Holly Anderton, Kate E. Lawlor, Najoua Lalaoui, Andrew J. Kueh, Vik Ven Eng, Rebecca L. Ambrose, Marco J. Herold, Andre L. Samson, Rebecca Feltham, James M. Murphy, Gregor Ebert, Jaclyn S. Pearson, James E. Vince
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104632- (2022)
Summary: Pathogen recognition and TNF receptors signal via receptor interacting serine/threonine kinase-3 (RIPK3) to cause cell death, including MLKL-mediated necroptosis and caspase-8-dependent apoptosis. However, the post-translational control of R
Externí odkaz:
https://doaj.org/article/3caa971ec6024a6691ed27fdce5d0571