Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Jaclyn P, Kerr"'
Autor:
Adelaida R. Palla, Keren I. Hilgendorf, Ann V. Yang, Jaclyn P. Kerr, Aaron C. Hinken, Janos Demeter, Peggy Kraft, Nancie A. Mooney, Nora Yucel, David M. Burns, Yu Xin Wang, Peter K. Jackson, Helen M. Blau
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Repair of muscle damage requires muscle stem cells, which lose regenerative capacity with aging. Here, the authors show that a sensory organelle, the primary cilium, is critical for muscle stem cell proliferation during regeneration and lost with agi
Externí odkaz:
https://doaj.org/article/1cb547b9df374953936e2d5fd08f29bc
Autor:
Hengtao Zhang, Victoria Graham Bryson, Chaojian Wang, TianYu Li, Jaclyn P. Kerr, Rebecca Wilson, Deborah M. Muoio, Robert J. Bloch, Christopher Ward, Paul B. Rosenberg
Publikováno v:
JCI Insight, Vol 6, Iss 17 (2021)
Stromal interaction molecule 1 (STIM1), the sarcoplasmic reticulum (SR) transmembrane protein, activates store-operated Ca2+ entry (SOCE) in skeletal muscle and, thereby, coordinates Ca2+ homeostasis, Ca2+-dependent gene expression, and contractility
Externí odkaz:
https://doaj.org/article/4ef5dfde9ee943f784bb8eee0d805e3a
HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction-induced injury
Autor:
Andrew N. Billin, Samuel E. Honeycutt, Alan V. McDougal, Jaclyn P. Kerr, Zhe Chen, Johannes M. Freudenberg, Deepak K. Rajpal, Guizhen Luo, Henning Fritz Kramer, Robert S. Geske, Frank Fang, Bert Yao, Richard V. Clark, John Lepore, Alex Cobitz, Ram Miller, Kazunori Nosaka, Aaron C. Hinken, Alan J. Russell
Publikováno v:
Skeletal Muscle, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Background In muscular dystrophy and old age, skeletal muscle repair is compromised leading to fibrosis and fatty tissue accumulation. Therefore, therapies that protect skeletal muscle or enhance repair would be valuable medical treatments.
Externí odkaz:
https://doaj.org/article/e1f73e6f4eda4a62a3d79d3777de791e
Autor:
Brian L Ross, Brian Tenner, Michele L Markwardt, Adam Zviman, Guoli Shi, Jaclyn P Kerr, Nicole E Snell, Jennifer J McFarland, Joseph R Mauban, Christopher W Ward, Megan A Rizzo, Jin Zhang
Publikováno v:
eLife, Vol 7 (2018)
Genetically encoded fluorescent biosensors have revolutionized the study of signal transduction by enabling the real-time tracking of signaling activities in live cells. Investigating the interaction between signaling networks has become increasingly
Externí odkaz:
https://doaj.org/article/daf2e8e4686046bbbaeec9259aa19b87
Autor:
Andrew N. Billin, Samuel E. Honeycutt, Alan V. McDougal, Jaclyn P. Kerr, Zhe Chen, Johannes M. Freudenberg, Deepak K. Rajpal, Guizhen Luo, Henning Fritz Kramer, Robert S. Geske, Frank Fang, Bert Yao, Richard V. Clark, John Lepore, Alex Cobitz, Ram Miller, Kazunori Nosaka, Aaron C. Hinken, Alan J. Russell
Publikováno v:
Skeletal Muscle, Vol 8, Iss 1, Pp 1-1 (2018)
Following publication of the original article [1], the authors flagged that there is a discrepancy with the Availability of data and materials statement on page 12 of the article.
Externí odkaz:
https://doaj.org/article/d03026fdb79744668aebcc8fa062fee1
Autor:
Jaclyn P. Kerr, Joaquin Muriel, Robert J. Bloch, Richard M. Lovering, Emily Kleinhans-Welte, Andrea O'Neill
Publikováno v:
Am J Physiol Cell Physiol
Intermediate filaments (IFs) contribute to force transmission, cellular integrity, and signaling in skeletal muscle. We previously identified keratin 19 (Krt19) as a muscle IF protein. We now report the presence of a second type I muscle keratin, Krt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efbbb22eefa8dcebc3518c06559b99d3
https://doi.org/10.1152/ajpcell.00279.2019
https://doi.org/10.1152/ajpcell.00279.2019
Publikováno v:
Frontiers in Physiology, Vol 5 (2014)
The class of muscular dystrophies linked to the genetic ablation or mutation of dysferlin, including Limb Girdle Muscular Dystrophy 2B (LGMD2B) and Miyoshi Myopathy (MM), are late-onset degenerative diseases. In lieu of a genetic cure, treatments to
Externí odkaz:
https://doaj.org/article/fcfa4535555e44e8b83da703805ca9ac
Autor:
Ponvijay eKombairaju, Jaclyn P Kerr, Joseph A Roche, Stephen J.P Pratt, Richard M Lovering, Thomas E Sussan, Jung-Hyun eKim, Guoli eShi, Shyam eBiswal, Christopher William Ward
Publikováno v:
Frontiers in Physiology, Vol 5 (2014)
Oxidative stress is a critical disease modifier in the muscular dystrophies. Recently, we discovered a pathway by which mechanical stretch activates NADPH Oxidase 2 (NoX2) dependent ROS generation (X-ROS). Our work in dystrophic skeletal muscle revea
Externí odkaz:
https://doaj.org/article/902b720b7a07474fb6003d5a3c426a46
Autor:
Robert J. Bloch, Christopher W. Ward, Tianyu Li, Rebecca Wilson, Deborah M. Muoio, Chaojian Wang, Paul B. Rosenberg, Victoria Bryson, Hengtao Zhang, Jaclyn P. Kerr
Publikováno v:
JCI Insight
Stromal interaction molecule 1 (STIM1), the sarcoplasmic reticulum (SR) transmembrane protein, activates store-operated Ca2+ entry (SOCE) in skeletal muscle and, thereby, coordinates Ca2+ homeostasis, Ca2+-dependent gene expression, and contractility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46919ca2048052250fa1a78f09613b8
https://pubmed.ncbi.nlm.nih.gov/34494555
https://pubmed.ncbi.nlm.nih.gov/34494555
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Frontiers in Endocrinology
Bone Research
Frontiers in Endocrinology
Bone Research
We report here a method for the use of poly-l-lysine (PLL) to markedly improve the adenoviral transduction efficiency of primary murine osteoblasts and bone marrow stromal cells (BMSCs) in culture and in situ, which are typically difficult to transdu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e43871cc3e27ceb7a29eaeb62be6ee
https://www.frontiersin.org/article/10.3389/fendo.2020.00419/full
https://www.frontiersin.org/article/10.3389/fendo.2020.00419/full