Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jaclyn M. Einstein"'
Autor:
Anthony Q. Vu, Jaclyn M. Einstein, Eric L. Van Nostrand, Matthew DiSalvo, Alexander A. Shishkin, Wenhao Jin, Gene W. Yeo, Noorsher Ahmed, Nancy L. Allbritton, Emily C. Wheeler
Publikováno v:
Nature methods
Genetic screens using pooled CRISPR-based approaches are scalable and inexpensive, but restricted to standard readouts, including survival, proliferation and sortable markers. However, many biologically relevant cell states involve cellular and subce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e7bd463fdf50e56c271808894ef5b9d
http://europepmc.org/articles/PMC7357298
http://europepmc.org/articles/PMC7357298
Publikováno v:
RNA. 26:19-28
Direct RNA sequencing holds great promise for the de novo identification of RNA modifications at single-coordinate resolution; however, interpretation of raw sequencing output to discover modified bases remains a challenge. Using Oxford Nanopore's di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7df353a14a33e2f12fccadbfe79fb98c
https://doi.org/10.1261/rna.072785.119
https://doi.org/10.1261/rna.072785.119
Autor:
Xiang-Dong Fu, Dong-Er Zhang, Gene W. Yeo, Nathan D. Jayne, Dinghai Zheng, Amanda G Davis, Bin Tian, Jaclyn M. Einstein
Publikováno v:
Blood Adv
Blood advances, vol 5, iss 5
Blood advances, vol 5, iss 5
The proper balance of hematopoietic stem cell (HSC) self-renewal and differentiation is critical for normal hematopoiesis and is disrupted in hematologic malignancy. Among regulators of HSC fate, transcription factors have a well-defined central role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a087a307cd96584591fa3c527221daf
https://europepmc.org/articles/PMC7948294/
https://europepmc.org/articles/PMC7948294/
Publikováno v:
RNA (New York, N.Y.). 26(1)
Direct RNA sequencing holds great promise for the de novo identification of RNA modifications at single-coordinate resolution; however, interpretation of raw sequencing output to discover modified bases remains a challenge. Using Oxford Nanopore's di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::97cbc253d40cc683e4df97a12eaf0f99
https://pubmed.ncbi.nlm.nih.gov/31624092
https://pubmed.ncbi.nlm.nih.gov/31624092
Autor:
Gene W. Yeo, Jaclyn M. Einstein
Publikováno v:
Science. 354:705-706
Noncoding elements encompass more than 98% of the human genome and have been linked to regulatory sequences that contribute to human health and disease ( 1 ). Since the publication of the human genome sequence, considerable effort has been made to an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e84aa18e1b28d5073fd89d4714b5166
https://doi.org/10.1126/science.aak9849
https://doi.org/10.1126/science.aak9849