Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jaclyn M. Chasse"'
Autor:
Joel T. Welch, Vincent Jacques, Heribert Schmitt-Willich, Jeffrey S. Troughton, Jaclyn M. Chasse, Peter Caravan, Stephane Dumas, Wei-Chuan Sun
Publikováno v:
Investigative Radiology. 45:600-612
Rationale and Objectives:The donor atoms that bind to gadolinium in contrast agents influence inner-sphere water exchange and electronic relaxation, both of which determine observed relaxivity. The effect of these molecular parameters on relaxivity i
Autor:
Jaclyn M. Chasse, Qing Deng, Kirsten Overoye-Chan, Peter Caravan, Richard J. Looby, Steffi K. Koerner, Stephan G. Zech, Thomas J. McMurry, Andrew Kolodziej
Publikováno v:
Journal of the American Chemical Society. 130:6025-6039
Thrombus (blood clot) is implicated in a number of life threatening diseases, e.g., heart attack, stroke, pulmonary embolism. EP-2104R is an MRI contrast agent designed to detect thrombus by binding to the protein fibrin, present in all thrombi. EP-2
Autor:
Marga Spiller, Normand J. Cloutier, Randall B. Lauffer, Peter Caravan, Thomas J. Mcmurry, Jeffrey J. Ellison, Jaclyn M. Chasse, Claudio Luchinat, Giacomo Parigi, Sarah A. McDermid
Publikováno v:
Inorganic Chemistry. 46:6632-6639
The amphiphilic gadolinium complex MS-325 ((trisodium-{(2-(R)-[(4,4-diphenylcyclohexyl) phosphonooxymethyl] diethylenetriaminepentaacetato) (aquo)gadolinium(III)}) is a contrast agent for magnetic resonance angiography (MRA). MS-325 consists of two s
Publikováno v:
Investigative Radiology. 41:229-243
RATIONALE AND OBJECTIVES We sought to determine whether there is a species dependence on plasma protein and serum album binding and/or relaxivity of the MR contrast agent MS-325. METHODS Equilibrium binding of MS-325 to plasma proteins or purified se
Autor:
Peter Caravan, Stephane Dumas, Jeffrey S. Troughton, Jaclyn M. Chasse, Normand J. Cloutier, Thomas J. McMurry
Publikováno v:
Australian Journal of Chemistry. 61:682
EP-647 is a serum albumin-targeted magnetic resonance imaging contrast agent comprising a GdDTPA (DTPA, diethylenetriaminepentaacetate) chelate for magnetic resonance signal generation linked via a phosphodiester to a substituted biphenyl for albumin
Autor:
Stéphane Dumas, Jeffrey S. Troughton, Normand J. Cloutier, Jaclyn M. Chasse, Thomas J. McMurry, Peter Caravan
Publikováno v:
Australian Journal of Chemistry; Sep2008, Vol. 61 Issue 9, p682-686, 5p