Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jackson M Baumann"'
Autor:
Oleg Yarishkin, Tam T. T. Phuong, Felix Vazquez-Chona, Jacques Bertrand, Joseph van Battenburg-Sherwood, Sarah N. Redmon, Christopher N. Rudzitis, Monika Lakk, Jackson M. Baumann, Marc Freichel, Eun-Mi Hwang, Darryl Overby, David Križaj
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Trabecular meshwork (TM) cells are phagocytic cells that employ mechanotransduction to actively regulate intraocular pressure. Similar to macrophages, they express scavenger receptors and participate in antigen presentation within the immunosuppressi
Externí odkaz:
https://doaj.org/article/e878d86628904c698824107f4feebaa7
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Retinal ganglion cells (RGCs) are projection neurons that transmit the visual signal from the retina to the brain. Their excitability and survival can be strongly influenced by mechanical stressors, temperature, lipid metabolites, and inflammatory me
Externí odkaz:
https://doaj.org/article/ae490e8af6334ab39a8f3ed49deb741c
Autor:
Monika Lakk, Tam T. T. Phuong, David Križaj, Michael L. De Ieso, W. Daniel Stamer, Chad A Sundberg, Jackson M Baumann, Oleg Yarishkin, Félix R. Vázquez-Chona, Christopher N. Rudzitis
Publikováno v:
J Physiol
Key points Trabecular meshwork (TM) is a highly mechanosensitive tissue in the eye that regulates intraocular pressure through the control of aqueous humour drainage. Its dysfunction underlies the progression of glaucoma but neither the mechanisms th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7fdd7c2cf14829075f73d19c8663f0
https://doi.org/10.1113/jp281011
https://doi.org/10.1113/jp281011
Autor:
Oleg Yarishkin, Tam T. T. Phuong, Felix Vazquez-Chona, Jacques Bertrand, Sarah N. Redmon, Monika Lakk, Christopher N. Rudzitis, Jackson M. Baumann, Eun Mi Hwang, Darryl Overby, David Križaj
Transduction of mechanical information is influenced by physical, chemical and thermal cues but the molecular mechanisms through which transducer activation shapes temporal signaling remain underexplored. In the present study, electrophysiology, hist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2c1436c235d401c52130e489784e386
https://doi.org/10.1101/2021.12.15.472700
https://doi.org/10.1101/2021.12.15.472700
Publikováno v:
Channels. 13:168-171
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::607633a73dcd0b21c48507496e36397a
https://doi.org/10.1080/19336950.2019.1618149
https://doi.org/10.1080/19336950.2019.1618149
Autor:
David Krizaj, C. N. Rudzitis, Félix R. Vázquez-Chona, Monika Lakk, M. L. De Ieso, Tam T. T. Phuong, Jackson M Baumann, Oleg Yarishkin, Chad A Sundberg, W. D. Stamer
Mechanosensitivity of the trabecular meshwork (TM) is a key determinant of intraocular pressure (IOP) yet our understanding of the molecular mechanisms that subserve it remains in its infancy. Here, we show that mechanosensitive Piezo1 channels modul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85f61c4dd70f125d41f9e951dbf3633f
https://doi.org/10.1101/2020.06.30.180653
https://doi.org/10.1101/2020.06.30.180653
Autor:
Mary Elizabeth Hartnett, Colin A. Bretz, Kenneth W. Olsen, Catherine Heurteaux, Monika Lakk, Tam T. T. Phuong, David Križaj, Jackson M Baumann, Oleg Yarishkin, Alan S. Crandall
Publikováno v:
Channels
Journal of General Physiology
Journal of General Physiology, Rockefeller University Press, 2018, 150 (12), pp.1660-1675. ⟨10.1085/jgp.201812179⟩
The Journal of General Physiology
Journal of General Physiology
Journal of General Physiology, Rockefeller University Press, 2018, 150 (12), pp.1660-1675. ⟨10.1085/jgp.201812179⟩
The Journal of General Physiology
The trabecular meshwork (TM) plays a fundamental role in intraocular pressure regulation, but its mechanotransduction pathway is poorly understood. Yarishkin et al. show that the mechanosensing channel TREK-1 regulates TM membrane potential, pressure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8df3cd022ee2f0ebbf3e6205b9b4b6e
https://pubmed.ncbi.nlm.nih.gov/31161865
https://pubmed.ncbi.nlm.nih.gov/31161865
Publikováno v:
Glia. 65(12)
Over- and underexposure to cholesterol activates glia in neurodegenerative brain and retinal diseases but the molecular targets of cholesterol in glial cells are not known. Here, we report that disruption of unesterified membrane cholesterol content
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0cf167ea8badeff4bea564f85fd37a
https://pubmed.ncbi.nlm.nih.gov/28856727
https://pubmed.ncbi.nlm.nih.gov/28856727