Výsledky vyhledávání - "Jackson L, Amaral"

Akademický článek

Synergistic Antifungal Activity of Synthetic Peptides and Antifungal Drugs against Candida albicans and C. parapsilosis Biofilms

Autor: Leandro P. Bezerra, Cleverson D. T. Freitas, Ayrles F. B. Silva, Jackson L. Amaral, Nilton A. S. Neto, Rafael G. G. Silva, Aura L. C. Parra, Gustavo H. Goldman, Jose T. A. Oliveira, Felipe P. Mesquita, Pedro F. N. Souza

Publikováno v: Antibiotics, Vol 11, Iss 5, p 553 (2022)

C. albicans and C. parapsilosis are biofilm-forming yeasts responsible for bloodstream infections that can cause death. Synthetic antimicrobial peptides (SAMPs) are considered to be new weapons to combat these infections, alone or combined with drugs

Externí odkaz: https://doaj.org/article/0487aa639fce47c78229b3eca71e07de

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Combined antibiofilm activity of synthetic peptides and antifungal drugs against Candida spp

Autor: Leandro P Bezerra, Ayrles FB Silva, Ralph Santos-Oliveira, Luciana MR Alencar, Jackson L Amaral, Nilton AS Neto, Rafael GG Silva, Mônica O Belém, Claudia R de Andrade, Jose TA Oliveira, Cleverson DT Freitas, Pedro FN Souza

Publikováno v: Future Microbiology. 17:1133-1146

Introduction: Candida krusei and Candida albicans are biofilm-forming drug-resistant yeasts that cause bloodstream infections that can lead to death. Materials & methods: nystatin and itraconazole were combined with two synthetic peptides, PepGAT and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6b82a09d8c4ff59a35a5bc0784b4e45c
https://doi.org/10.2217/fmb-2022-0053

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The spike glycoprotein of SARS-CoV-2: A review of how mutations of spike glycoproteins have driven the emergence of variants with high transmissibility and immune escape

Autor: Pedro F N, Souza, Felipe P, Mesquita, Jackson L, Amaral, Patrícia G C, Landim, Karollyny R P, Lima, Marília B, Costa, Izabelle R, Farias, Mônica O, Belém, Yago O, Pinto, Heline H T, Moreira, Ilana C L, Magalhaes, Débora S C M, Castelo-Branco, Raquel C, Montenegro, Claudia R, de Andrade

Publikováno v: International Journal of Biological Macromolecules. 208:105-125

Late in 2019, SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2) emerged, causing an unknown type of pneumonia today called coronaviruses disease 2019 (COVID-19). COVID-19 is still an ongoing global outbreak that has claimed and threatened

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abfb1e9e67d93e7d16811116ee228b1e
https://doi.org/10.1016/j.ijbiomac.2022.03.058

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Neutralizing Effect of Synthetic Peptides toward SARS-CoV-2

Autor: Pedro F.N. Souza, Maurício F. vanTilburg, Felipe P. Mesquita, Jackson L. Amaral, Luina B. Lima, Raquel C. Montenegro, Francisco E.S. Lopes, Rafael X. Martins, Leonardo Vieira, Davi F. Farias, Ana C. O. Monteiro-Moreira, Cleverson D.T. Freitas, Arnaldo S. Bezerra, Maria I. F. Guedes, Débora S.C.M. Castelo-Branco, Jose T.A. Oliveira

Publikováno v: ACS Omega. 7:16222-16234

The outbreak caused by SARS-CoV-2 has taken many lives worldwide. Although vaccination has started, the development of drugs to either alleviate or abolish symptoms of COVID-19 is still necessary. Here, four synthetic peptides were assayed regarding

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::956349ebcba6ba09ef2a15a2d526a22b
https://doi.org/10.1021/acsomega.2c02203

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Characterization of the binding interaction between atrazine and human serum albumin: Fluorescence spectroscopy, molecular dynamics and quantum biochemistry

Autor: Victor L.B. França, Jackson L. Amaral, Yandara A. Martins, Ewerton W.S. Caetano, Kellen Brunaldi, Valder N. Freire

Publikováno v: Chemico-biological interactions. 366

Atrazine (ATR), one of the most used herbicides worldwide, causes persistent contamination of water and soil due to its high resistance to degradation. ATR is associated with low fertility and increased risk of prostate cancer in humans, as well as b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8d0cedc5eed656d69180aaa7d4cbd2
https://pubmed.ncbi.nlm.nih.gov/36037875

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Peptide fraction from latex of Calotropis procera exhibits antifungal and insecticidal activities

Autor: Cleverson D.T. Freitas, Ghulam Hussain, Márcio V. Ramos, Pedro F.N. Souza, Jackson L. Amaral, João Pedro Viana Rodrigues

Publikováno v: Arthropod-Plant Interactions. 15:431-438

Latex is an endogenous fluid exuded by some plants after injury. It is rich in different molecules and has shown many biological activities against different fungi and insects. This work aimed to isolate a peptide fraction from Calotropis procera (Pe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e7e667dd11530e51513583649ebf49d6
https://doi.org/10.1007/s11829-021-09828-2

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ACE2-derived peptides interact with the RBD domain of SARS-CoV-2 spike glycoprotein, disrupting the interaction with the human ACE2 receptor

Autor: Leandro P. Bezerra, Pedro F.N. Souza, Jose T.A. Oliveira, Cleverson D.T. Freitas, Jackson L. Amaral, Valder N. Freire, Francisco E.S. Lopes

Publikováno v: Journal of Biomolecular Structure and Dynamics
Journal of Biomolecular Structure & Dynamics
article-version (VoR) Version of Record

Vaccines could be the solution to the current SARS-CoV-2 outbreak. However, some studies have shown that the immunological memory only lasts three months. Thus, it is imperative to develop pharmacological treatments to cope with COVID-19. Here, the i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b987b3b596a12dd9b7a9f029c5f19bd0
https://doi.org/10.1080/07391102.2020.1871415

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Quantum biochemistry in cancer immunotherapy: New insights about CTLA-4/ipilimumab and design of ipilimumab-derived peptides with high potential in cancer treatment

Autor: Jackson L. Amaral, Hernandes F. Carvalho, Pablo A. de Morais, Valder N. Freire, Samuel José Mendes dos Santos, Pedro F.N. Souza, F. F. Maia

Publikováno v: Molecular Immunology. 127:203-211

Cancer is a group of diseases involving disordered growth of abnormal cells with the potential to invade and spread to other parts of the body. Today, immunotherapy is the most efficient treatment, with fewer side effects. Notably, the employment of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6197cd9490bb129fe04368f76558524f
https://doi.org/10.1016/j.molimm.2020.09.013

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Technological forecasting: liposomes as drug delivery vehicles with therapeutic potential

Autor: Larisse Maia Mesquita, Jackson L. Amaral, Luca Milério Andrade, Ana Lúcia Ponte Freitas, Lana Grasiela Alves Marques, João Pedro Viana Rodrigues, Dayara de Oliveira Silva

Publikováno v: Revista GEINTEC, Vol 9, Iss 3, Pp 5058-5066 (2019)

A aplicacao de lipossomas para a administracao controlada de farmacos tem tido um grande impacto em muitas areas biomedicas. Verificou-se que eles sao beneficos para a estabilizacao de compostos terapeuticos, superacao de obstaculos a absorcao celula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdc52e5d5fb218301e044f9f6c7dc34e
http://www.revistageintec.net/index.php/revista/article/view/1062

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