Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jackson G. Thorp"'
Autor:
Adrian I. Campos, Aoibhe Mulcahy, Jackson G. Thorp, Naomi R. Wray, Enda M. Byrne, Penelope A. Lind, Sarah E. Medland, Nicholas G. Martin, Ian B. Hickie, Miguel E. Rentería
Publikováno v:
Communications Medicine, Vol 1, Iss 1, Pp 1-10 (2021)
Campos et al. study the genetic aetiology of antidepressant side effects. Using data from the Australian Genetics of Depression study, the authors show that polygenic risk scores for traits such as BMI, insomnia and headaches have a shared genetic ba
Externí odkaz:
https://doaj.org/article/c0fde98500264eae890623636a92ff20
Autor:
Brittany L. Mitchell, Jackson G. Thorp, David M. Evans, Dale R. Nyholt, Nicholas G. Martin, Michelle K. Lupton
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction Hearing loss has been identified as the potentially largest modifiable risk factor for Alzheimer's disease (AD), estimated to account for a similar increase in AD risk as the apolipoprotein E (APOE) gene. Methods We investigated
Externí odkaz:
https://doaj.org/article/49110122bef64dda81c89cb113a63d4b
Autor:
Jackson G. Thorp, Brittany L. Mitchell, Zachary F. Gerring, Jue-Sheng Ong, Puya Gharahkhani, Eske M. Derks, Michelle K. Lupton
Publikováno v:
Neurobiology of Aging. 119:127-135
Alzheimer's disease (AD) is predicted to affect 132 million people by 2050. Targeting modifiable lifestyle risk factors that are associated with an increased risk of AD could prevent a large proportion of dementia cases, allowing people to reach the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d168118e002e487847765508de26b23b
https://doi.org/10.1016/j.neurobiolaging.2022.07.011
https://doi.org/10.1016/j.neurobiolaging.2022.07.011
Publikováno v:
Nature Genetics. 54:1457-1465
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e87d88318cd6c3e350d9340d5370145b
https://doi.org/10.1038/s41588-022-01174-0
https://doi.org/10.1038/s41588-022-01174-0
Publikováno v:
Schizophrenia bulletin. 48(6)
Background and Hypothesis The nature of the robust association between cannabis use and schizophrenia remains undetermined. Plausible hypotheses explaining this relationship include the premise that cannabis use causes schizophrenia, increased liabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88c818ed5be2f7eec665c452288b88e3
https://pubmed.ncbi.nlm.nih.gov/35925031
https://pubmed.ncbi.nlm.nih.gov/35925031
Autor:
Jackson G. Thorp, Zachary F. Gerring, Lucía Colodro-Conde, Enda M. Byrne, Sarah E. Medland, Christel M. Middeldorp, Eske M. Derks
Publikováno v:
Psychiatry research, 321:115101. Elsevier Ireland Ltd
Background: Traumatic experiences are associated with increased risk for major depressive disorder (MDD). This study sought to determine the extent that trauma exposure, depression polygenic risk scores (PRS), and their interaction are associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::736d564296a0162ceaaf2127300d98f0
https://pure.amc.nl/en/publications/the-association-between-trauma-exposure-polygenic-risk-and-individual-depression-symptoms(fe875a94-b957-41d2-aa4b-71e32d75e360).html
https://pure.amc.nl/en/publications/the-association-between-trauma-exposure-polygenic-risk-and-individual-depression-symptoms(fe875a94-b957-41d2-aa4b-71e32d75e360).html
Publikováno v:
Eur J Hum Genet
Genome-wide association studies (GWASs) have identified thousands of risk loci for psychiatric and substance use phenotypes, however the biological consequences of these loci remain largely unknown. We performed a transcriptome-wide association study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1684db2ba19bab43a4d39bc4a6440cfd
https://europepmc.org/articles/PMC9090912/
https://europepmc.org/articles/PMC9090912/
Autor:
Asma M Aman, Luis M García-Marín, Jackson G Thorp, Adrian I Campos, Gabriel Cuellar-Partida, Nicholas G Martin, Miguel E Rentería
Publikováno v:
Human molecular genetics. 31(17)
Depression is one of the most common mental health disorders and one of the top causes of disability throughout the world. The present study sought to identify putative causal associations between depression and hundreds of complex human traits throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e17d5c254b3c45d205942bb7f23b754
https://pubmed.ncbi.nlm.nih.gov/35394011
https://pubmed.ncbi.nlm.nih.gov/35394011
Publikováno v:
Nature genetics. 54(10)
Genome-wide association studies have identified hundreds of robust genetic associations underlying psychiatric disorders and provided important biological insights into disease onset and progression. There is optimism that genetic findings will pave
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::75530b8d9a236bd61da5fce1862b5b08
https://pubmed.ncbi.nlm.nih.gov/36138228
https://pubmed.ncbi.nlm.nih.gov/36138228
Autor:
Nicholas G. Martin, Aoibhe Mulcahy, Naomi R. Wray, Sarah E. Medland, Penelope A. Lind, Miguel E. Rentería, Jackson G. Thorp, Adrian I. Campos, Ian B. Hickie, Enda M. Byrne
Publikováno v:
Communications Medicine, Vol 1, Iss 1, Pp 1-10 (2021)
Major depression is one of the most disabling health conditions internationally. In recent years, new generation antidepressant medicines have become very widely prescribed. While these medicines are efficacious, side effects are common and frequentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f0d2e9dbebd70db0c2821a69eff620
https://doi.org/10.1038/s43856-021-00046-8
https://doi.org/10.1038/s43856-021-00046-8