Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jackson Elisa Rose"'
Autor:
Patrick R. Maloney, Frank E. Ewing, Howard Harry R, Celeste Johnson, Jean Morrone, M. E. Newman, Gwendolyn L. Robinson, Jackson Elisa Rose, Anne W. Schmidt, Stevin H. Zorn, Jerome S. Furman, Seeger Thomas Francis, John A. Lowe, Patricia A. Seymour
Publikováno v:
Journal of Medicinal Chemistry. 39:143-148
A series of substituted phenethyl derivatives of 3-benzisothiazolylpiperazine incorporating potent D2 and 5-HT2A antagonist activity was investigated as an approach to a novel atypical antipsychotic agent. The in vitro profile of 8e from this series
Autor:
Stevin H. Zorn, Yoshihito Kanai, R.M. Snider, Osamu Suga, John A. Lowe, Jon Bordner, Susan E. Drozda, Stafford McLean, Jackson Elisa Rose, Megumi Tsuchiya, Atsushi Nagahisa, Jean Morrone, Dianne K. Bryce, Kelly P. Longo
Publikováno v:
Regulatory Peptides. 46:20-23
Studies with CP-96,345, a potent, selective, orally active, nonpeptide NK1 receptor antagonist, have provided considerable insight into SP pharmacology. Rather than being a primary neurotransmitter, SP prolongs the nociception produced by other neuro
Publikováno v:
Biochemical Journal. 291:369-374
Despite limiting side-effects, lithium is the drug of choice for the treatment of bipolar depression. Its action may be due, in part, to its ability to dampen phosphatidylinositol turnover by inhibiting myo-inositol monophosphatase. Beryllium has bee
Autor:
Shelli J. Schomaker, Jackson Elisa Rose, Diane L. Joslin, Ingrid M. Pruimboom-Brees, Carolyn Rose Kilroy, David E. Amacher
Publikováno v:
Drug and chemical toxicology. 31(4)
Dexamethasone (DEXA) administration has been associated with serum alanine aminotransferase (ALT) elevations that may result from enhanced ALT expression. The aim of our current study was to compare liver vs. serum ALT activity and to examine the ons
Autor:
Sanner Mark Allen, Desai Kishor A, Celeste Johnson, Jae S. Lee, Judith L. Collins, Audrey R. Dunaiskis, W. Stephen Faraci, Cecilia C. Di Prete, Angela Trozzi, Thomas Allen Chappie, Patricia A. Seymour, Jean Morrone, David B. Duignan, Stevin H. Zorn, Mark J. Majchrzak, Jackson Elisa Rose, Fliri Anton F J
Publikováno v:
Bioorganicmedicinal chemistry letters. 8(7)
A series of novel, potent and selective pyrido[1,2-a]pyrazine dopamine D4 receptor antagonists are reported including CP-293,019 (D4 Ki = 3.4 nM, D2 Ki > 3,310 nM), which also inhibits apomorphine-induced hyperlocomotion in rats after oral dosing.
Autor:
Yoshihito Kanai, R.M. Snider, Kelly P. Longo, Osamu Suga, Jean Morrone, M. Nakagaki, Stevin H. Zorn, Susan E. Drozda, Jackson Elisa Rose, Atsushi Nagahisa, John A. Lowe
Publikováno v:
Regulatory peptides. 46(1-2)
Autor:
R. Michael Snider, John A. Lowe, Stevin H. Zorn, Jackson Elisa Rose, Stafford McLean, Kelly P. Longo, Jean Morrone, Dianne K. Bryce, Susan E. Drozda
Publikováno v:
Journal of Medicinal Chemistry. 35:4768-4768