Deployment and assessment of a deep learning model for real-time detection of anal precancer with high frame rate high-resolution microendoscopy

Autor: David Brenes, Alex Kortum, Jackson Coole, Jennifer Carns, Richard Schwarz, Imran Vohra, Rebecca Richards-Kortum, Yuxin Liu, Zhenjian Cai, Keith Sigel, Sharmila Anandasabapathy, Michael Gaisa, Elizabeth Chiao

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)

Abstract Anal cancer incidence is significantly higher in people living with HIV as HIV increases the oncogenic potential of human papillomavirus. The incidence of anal cancer in the United States has recently increased, with diagnosis and treatment

Externí odkaz: https://doaj.org/article/2623565ae40242b584c34e86ee4f15d0

Real-time isothermal nucleic acid amplification detection in resource-limited settings: a description of an open-source miniature fluorimeter

Autor: Jackson Coole, BS, Alex Kortum, MSc, Yubo Tang, PhD, Imran Vohra, BS, Mary Natoli, PhD, Kathryn Kundrod, PhD, Rebecca Richards-Kortum, PhD

Publikováno v: The Lancet Global Health, Vol 9, Iss , Pp S6- (2021)

Background: The detection and quantification of nucleic acids traditionally relies on PCR, which requires the use of expensive thermocyclers with integrated fluorescence detection of amplicons. While isothermal nucleic acid amplification technologies

Externí odkaz: https://doaj.org/article/5072a5125cbb464ba5aaa7d89e0ec380

Multi-modal mobile colposcope for real-time cervical precancer detection: a pilot study in Mozambique

Autor: Jackson Coole, Ruchika Mitbander, David Brenes, Alex Kortum, Yajur Maker, Eliane Monteiro, Arlete Mariano, Ricardina Rangeiro, Guilhermina Tivir, Hira Atif, Celda Mavume, Nafissa Osman, Carla Carrilho, Rosita Mugolo, Andrea Neves, Shababa Matin, Richard A. Schwarz, Jennifer Carns, Mila P. Salcedo, Nirmala Ramanujam, Ellen Baker, Cesaltina Lorenzoni, Kathleen M. Schmeler, Rebecca R. Richards-Kortum

Publikováno v: Optics and Biophotonics in Low-Resource Settings IX.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f6b5804196a67203c34c45c773143a15
https://doi.org/10.1117/12.2650551

Development of Low-Cost Point-of-Care Technologies for Cervical Cancer Prevention Based on a Single-Board Computer

Autor: Chelsey A. Smith, Mauricio Maza, Sonia G. Parra, Eduardo Carranza, Brady Hunt, Kathleen M. Schmeler, Jackson Coole, Rebecca Richards-Kortum, Pelham Keahey

Publikováno v: IEEE Journal of Translational Engineering in Health and Medicine, Vol 8, Pp 1-10 (2020)
IEEE Journal of Translational Engineering in Health and Medicine

Cervical cancer disproportionally affects women in low- and middle-income countries, in part due to the difficulty of implementing existing cervical cancer screening and diagnostic technologies in low-resource settings. Single-board computers offer a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b4818947465a4388cc8de7a48d47221
https://ieeexplore.ieee.org/document/8978694/

Real-Time, In Vivo Projection of High-Risk Maps for Oral Biopsy Guidance

Autor: Hawraa Badaoui, Richard A. Schwarz, Ruchika Mitbander, Jackson Coole, Yubo Tang, David Brenes, Imran Vohra, Jennifer Carns, Rebecca Richards-Kortum, Ann M. Gillenwater

Publikováno v: Biophotonics Congress: Biomedical Optics 2020 (Translational, Microscopy, OCT, OTS, BRAIN).

A system that acquires white-light and autofluorescence images of the oral cavity, generates a map of high-risk areas, and projects the map directly onto the tissue is introduced. The potential for biopsy guidance is discussed.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::36e43639f14eaca015d52bd704119947
https://doi.org/10.1364/translational.2020.ttu4b.5