Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Jackson, Emanuel"'
Autor:
Brian Maina Ogoti, Victor Riitho, Johanna Wildemann, Nyamai Mutono, Julia Tesch, Jordi Rodon, Kaneemozhe Harichandran, Jackson Emanuel, Elisabeth Möncke-Buchner, Stella Kiambi, Julius Oyugi, Marianne Mureithi, Victor M. Corman, Christian Drosten, Samuel M. Thumbi, Marcel A. Müller
Publikováno v:
Emerging Infectious Diseases, Vol 30, Iss 3, Pp 581-585 (2024)
Middle East respiratory syndrome coronavirus (MERS-CoV) is endemic in dromedaries in Africa, but camel-to-human transmission is limited. Sustained 12-month sampling of dromedaries in a Kenya abattoir hub showed biphasic MERS-CoV incidence; peak detec
Externí odkaz:
https://doaj.org/article/12e88a5687aa49c68692c936c399ff61
Autor:
Simon Schröder, Anja Richter, Talitha Veith, Jackson Emanuel, Luca Gudermann, Kirstin Friedmann, Lara M. Jeworowski, Barbara Mühlemann, Terry C. Jones, Marcel A. Müller, Victor M. Corman, Christian Drosten
Publikováno v:
Virology Journal, Vol 20, Iss 1, Pp 1-13 (2023)
Abstract Background Intrinsic fitness costs are likely to have guided the selection of lineage-determining mutations during emergence of variants of SARS-CoV-2. Whereas changes in receptor affinity and antibody neutralization have been thoroughly map
Externí odkaz:
https://doaj.org/article/faa93fcd2deb4a35b9efcfc3602c8045
Autor:
Jackson Emanuel, Jan Papies, Celine Galander, Julia M. Adler, Nicolas Heinemann, Kathrin Eschke, Sophie Merz, Hannah Pischon, Ruben Rose, Andi Krumbholz, Žarko Kulić, Martin D. Lehner, Jakob Trimpert, Marcel A. Müller
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
The occurrence of immune-evasive SARS-CoV-2 strains emphasizes the importance to search for broad-acting antiviral compounds. Our previous in vitro study showed that Pelargonium sidoides DC. root extract EPs® 7630 has combined antiviral and immunomo
Externí odkaz:
https://doaj.org/article/044307d14f644aaf80e4e9beb57d435d
Autor:
Julia Kazmierski, Kirstin Friedmann, Dylan Postmus, Jackson Emanuel, Cornelius Fischer, Jenny Jansen, Anja Richter, Laure Bosquillon de Jarcy, Christiane Schüler, Madlen Sohn, Sascha Sauer, Christian Drosten, Antoine‐Emmanuel Saliba, Leif Erik Sander, Marcel A Müller, Daniela Niemeyer, Christine Goffinet
Publikováno v:
Molecular Systems Biology, Vol 18, Iss 8, Pp 1-16 (2022)
Abstract Cell‐intrinsic responses mounted in PBMCs during mild and severe COVID‐19 differ quantitatively and qualitatively. Whether they are triggered by signals emitted by productively infected cells of the respiratory tract or result from physi
Externí odkaz:
https://doaj.org/article/bd2eb001419145ec893ee0b1a1a9d093
Autor:
Daniela Niemeyer, Saskia Stenzel, Talitha Veith, Simon Schroeder, Kirstin Friedmann, Friderike Weege, Jakob Trimpert, Julian Heinze, Anja Richter, Jenny Jansen, Jackson Emanuel, Julia Kazmierski, Fabian Pott, Lara M Jeworowski, Ruth Olmer, Mark-Christian Jaboreck, Beate Tenner, Jan Papies, Felix Walper, Marie L Schmidt, Nicolas Heinemann, Elisabeth Möncke-Buchner, Morris Baumgardt, Karen Hoffmann, Marek Widera, Tran Thi Nhu Thao, Anita Balázs, Jessica Schulze, Christin Mache, Terry C Jones, Markus Morkel, Sandra Ciesek, Leif G Hanitsch, Marcus A Mall, Andreas C Hocke, Volker Thiel, Klaus Osterrieder, Thorsten Wolff, Ulrich Martin, Victor M Corman, Marcel A Müller, Christine Goffinet, Christian Drosten
Publikováno v:
PLoS Biology, Vol 20, Iss 11, p e3001871 (2022)
Epidemiological data demonstrate that Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) Alpha and Delta are more transmissible, infectious, and pathogenic than previous variants. Phenotypic properties of VOC rema
Externí odkaz:
https://doaj.org/article/f439c20a5aa647faba500c0b3fd9f88a
Autor:
Nils C. Gassen, Jan Papies, Thomas Bajaj, Jackson Emanuel, Frederik Dethloff, Robert Lorenz Chua, Jakob Trimpert, Nicolas Heinemann, Christine Niemeyer, Friderike Weege, Katja Hönzke, Tom Aschman, Daniel E. Heinz, Katja Weckmann, Tim Ebert, Andreas Zellner, Martina Lennarz, Emanuel Wyler, Simon Schroeder, Anja Richter, Daniela Niemeyer, Karen Hoffmann, Thomas F. Meyer, Frank L. Heppner, Victor M. Corman, Markus Landthaler, Andreas C. Hocke, Markus Morkel, Nikolaus Osterrieder, Christian Conrad, Roland Eils, Helena Radbruch, Patrick Giavalisco, Christian Drosten, Marcel A. Müller
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Viruses manipulate host cell pathways to support infection. Here the authors show that SARS-CoV-2 infection modulates cellular metabolism and limits autophagy, and identify druggable host pathways for virus inhibition.
Externí odkaz:
https://doaj.org/article/a210cbf8766241fd8d824076b3b287b5
Autor:
Jan Papies, Jackson Emanuel, Nicolas Heinemann, Žarko Kulić, Simon Schroeder, Beate Tenner, Martin D. Lehner, Georg Seifert, Marcel A. Müller
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/ba6232004d3f456f984fd86bfa12be59
Autor:
Jan Papies, Jackson Emanuel, Nicolas Heinemann, Žarko Kulić, Simon Schroeder, Beate Tenner, Martin D. Lehner, Georg Seifert, Marcel A. Müller
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Treatment options for COVID-19 are currently limited. Drugs reducing both viral loads and SARS-CoV-2-induced inflammatory responses would be ideal candidates for COVID-19 therapeutics. Previous in vitro and clinical studies suggest that the proprieta
Externí odkaz:
https://doaj.org/article/9631bde06b974129a613201d9045a8ac
Autor:
Keesha Matz, Jackson Emanuel, Julie Callison, Don Gardner, Rebecca Rosenke, Reinaldo Mercado-Hernandez, Brandi N. Williamson, Heinz Feldmann, Andrea Marzi
Publikováno v:
Microorganisms, Vol 9, Iss 6, p 1178 (2021)
Zika virus (ZIKV), a member of the Flaviviridae family, is an important human pathogen that has caused epidemics in Africa, Southeast Asia, and the Americas. No licensed treatments for ZIKV disease are currently available. Favipiravir (T-705; 6-fluor
Externí odkaz:
https://doaj.org/article/392f68027eca4e5fa5d1e080bac02e8f
Autor:
Andrea Marzi, Jackson Emanuel, Julie Callison, Kristin L. McNally, Nicolette Arndt, Spencer Chadinha, Cynthia Martellaro, Rebecca Rosenke, Dana P. Scott, David Safronetz, Stephen S. Whitehead, Sonja M. Best, Heinz Feldmann
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
The common small animal disease models for Zika virus (ZIKV) are mice lacking the interferon responses, but infection of interferon receptor α/β knock out (IFNAR−/−) mice is not uniformly lethal particularly in older animals. Here we sought to
Externí odkaz:
https://doaj.org/article/acca1c64424048a7807cc7fc4e2b43ad