Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Jacklynn V, Egger"'
Autor:
Michael Offin, Jennifer L. Sauter, Sam E. Tischfield, Jacklynn V. Egger, Shweta Chavan, Nisargbhai S. Shah, Parvathy Manoj, Katia Ventura, Viola Allaj, Elisa de Stanchina, William Travis, Marc Ladanyi, Andreas Rimner, Valerie W. Rusch, Prasad S. Adusumilli, John T. Poirier, Marjorie G. Zauderer, Charles M. Rudin, Triparna Sen
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-19 (2022)
Abstract Background Diffuse pleural mesothelioma (DPM) is an aggressive malignancy that, despite recent treatment advances, has unacceptably poor outcomes. Therapeutic research in DPM is inhibited by a paucity of preclinical models that faithfully re
Externí odkaz:
https://doaj.org/article/7bae9e3ad4f54b39847547d219cf9c55
Autor:
Yuan Chen, Biagio Ricciuti, Matthew D Hellmann, Hira Rizvi, Mark M Awad, Giuseppe Lamberti, Arielle Elkrief, Jamie E Chaft, Xinan Wang, Samantha Brown, Charles M Rudin, Joao M Victor Alessi, Isabel R Preeshagul, Federica Pecci, Alessandro Di Federico, Jacklynn V Egger, Gregory J Riely, Mark G Kris, Marc Ladanyi, Ronglai Shen, Adam J Schoenfeld
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 7 (2023)
Background Single-agent PD-(L)1 blockade (IO) alone or in combination with chemotherapy (Chemotherapy-IO) is approved first-line therapies in patients with advanced lung adenocarcinomas (LUADs) with PD-L1 expression ≥1%. These regimens have not bee
Externí odkaz:
https://doaj.org/article/1db67c48820e42a9b021621d9022be62
Autor:
Rebecca Caeser, Jacklynn V. Egger, Shweta Chavan, Nicholas D. Socci, Caitlin Byrne Jones, Faruk Erdem Kombak, Marina Asher, Michael H. Roehrl, Nisargbhai S. Shah, Viola Allaj, Parvathy Manoj, Sam E. Tischfield, Amanda Kulick, Maximiliano Meneses, Christine A. Iacobuzio-Donahue, W. Victoria Lai, Umeshkumar Bhanot, Marina K. Baine, Natasha Rekhtman, Travis J. Hollmann, Elisa de Stanchina, John T. Poirier, Charles M. Rudin, Triparna Sen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Creating accurate models of small cell lung cancer is essential to ensure the clinical relevance of results. Here, the authors create patient derived xenograft models from 33 patients and show, through multi-omics sequencing, that these models retain
Externí odkaz:
https://doaj.org/article/6db844e570e04ea595ba52c8f6bba923
Autor:
Joao V. Alessi, Arielle Elkrief, Biagio Ricciuti, Xinan Wang, Alessio Cortellini, Victor R. Vaz, Giuseppe Lamberti, Rosa L. Frias, Deepti Venkatraman, Claudia A.M. Fulgenzi, Federica Pecci, Gonzalo Recondo, Alessandro Di Federico, Adriana Barrichello, Hyesun Park, Mizuki Nishino, Grace M. Hambelton, Jacklynn V. Egger, Marc Ladanyi, Subba Digumarthy, Bruce E. Johnson, David C. Christiani, Xihong Lin, Justin F. Gainor, Jessica J. Lin, David J. Pinato, Adam J. Schoenfeld, Mark M. Awad
Publikováno v:
Journal of Thoracic Oncology. 18:731-743
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::356c243e352512e0daaaecb0919e16e9
https://doi.org/10.1016/j.jtho.2023.01.091
https://doi.org/10.1016/j.jtho.2023.01.091
Autor:
Michael Offin, Dilanka L. De Silva, Jennifer L. Sauter, Jacklynn V. Egger, Ellen Yorke, Prasad S. Adusumilli, Andreas Rimner, Valerie W. Rusch, Marjorie G. Zauderer
Publikováno v:
Journal of Thoracic Oncology. 17:1428-1432
Primary pericardial mesothelioma (PPM) has no accepted standard-of-care treatment options with management and outcomes often extrapolated from diffuse pleural mesothelioma. Disease-specific research is needed to better define PPM. We report our insti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e396e9746017a27da5c50595d697b44c
https://doi.org/10.1016/j.jtho.2022.08.017
https://doi.org/10.1016/j.jtho.2022.08.017
Autor:
Rami S, Vanguri, Jia, Luo, Andrew T, Aukerman, Jacklynn V, Egger, Christopher J, Fong, Natally, Horvat, Andrew, Pagano, Jose de Arimateia Batista, Araujo-Filho, Luke, Geneslaw, Hira, Rizvi, Ramon, Sosa, Kevin M, Boehm, Soo-Ryum, Yang, Francis M, Bodd, Katia, Ventura, Travis J, Hollmann, Michelle S, Ginsberg, Jianjiong, Gao, Matthew D, Hellmann, Jennifer L, Sauter, Rami, Vanguri
Publikováno v:
Nature Cancer. 3:1151-1164
Immunotherapy is used to treat almost all patients with advanced non-small cell lung cancer (NSCLC); however, identifying robust predictive biomarkers remains challenging. Here we show the predictive capacity of integrating medical imaging, histopath
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bfb7a6cb9f78cfb063ef647fdfe3c1f
https://doi.org/10.1038/s43018-022-00416-8
https://doi.org/10.1038/s43018-022-00416-8
Autor:
Charles M. Rudin, David Balli, W. Victoria Lai, Allison L. Richards, Evelyn Nguyen, Jacklynn V. Egger, Noura J. Choudhury, Triparna Sen, Andrew Chow, John T. Poirier, William J. Geese, Matthew D. Hellmann, Ann Forslund
Publikováno v:
Journal of Thoracic Oncology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3833d1e08300c305f6bde04c3d96355c
https://doi.org/10.1016/j.jtho.2023.05.008
https://doi.org/10.1016/j.jtho.2023.05.008
Autor:
Christopher A. Febres-Aldana, Jason C. Chang, Ryan Ptashkin, Yuhan Wang, Erika Gedvilaite, Marina K. Baine, William D. Travis, Katia Ventura, Francis Bodd, Helena A. Yu, Alvaro Quintanal-Villalonga, W. Victoria Lai, Jacklynn V. Egger, Michael Offin, Marc Ladanyi, Charles M. Rudin, Natasha Rekhtman
Publikováno v:
Clin Cancer Res
Purpose: RB1 mutations and loss of retinoblastoma (Rb) expression represent consistent but not entirely invariable hallmarks of small cell lung cancer (SCLC). The prevalence and characteristics of SCLC retaining wild-type Rb are not well-established.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd5e55d53ac0f03d3e4ac7f6346fa1ae
https://doi.org/10.1158/1078-0432.ccr-22-1115
https://doi.org/10.1158/1078-0432.ccr-22-1115
Autor:
Adam J. Schoenfeld, Hira A. Rizvi, Danish Memon, Narek Shaverdian, Matthew J. Bott, Jennifer L. Sauter, C. Jillian Tsai, Jayon Lihm, David Hoyos, Andrew J. Plodkowski, Rocio Perez-Johnston, Peter Sawan, Jacklynn V. Egger, Benjamin D. Greenbaum, Andreas Rimner, Gregory J. Riely, Charles M. Rudin, Valerie W. Rusch, Daniel R. Gomez, Matthew D. Hellmann
Publikováno v:
Clinical Cancer Research. 28:3797-3803
Purpose: Clinical patterns and the associated optimal management of acquired resistance to PD-(L)1 blockade are poorly understood. Experimental Design: All cases of metastatic lung cancer treated with PD-(L)1 blockade at Memorial Sloan Kettering were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0028fe3841fff93e2b97cef720ffcb40
https://doi.org/10.1158/1078-0432.ccr-22-0657
https://doi.org/10.1158/1078-0432.ccr-22-0657
Autor:
Soo-Ryum Yang, Rowanne S. Spencer, Andrea Cercek, Garrett M. Nash, Jacklynn V. Egger, William D. Travis, Mark G. Kris, Gowtham Jayakumaran, Jennifer L. Sauter, Jessica Lopardo, Marjorie G. Zauderer, M. Offin, Marc Ladanyi
Publikováno v:
Journal of Thoracic Oncology. 17:455-460
Background Malignant peritoneal mesothelioma (MPeM) is clinically distinct and less studied than malignant pleural mesothelioma. We report the genomic and immunophenotypic features of a prospectively collected MPeM cohort. Methods Next-generation seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d292e357222186cbe10e722c21ea329
https://doi.org/10.1016/j.jtho.2021.09.012
https://doi.org/10.1016/j.jtho.2021.09.012