Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jacklynn Egger"'
Autor:
Francesca Chemi, Simon P. Pearce, Alexandra Clipson, Steven M. Hill, Alicia-Marie Conway, Sophie A. Richardson, Katarzyna Kamieniecka, Rebecca Caeser, Daniel J. White, Sumitra Mohan, Victoria Foy, Kathryn L. Simpson, Melanie Galvin, Kristopher K. Frese, Lynsey Priest, Jacklynn Egger, Alastair Kerr, Pierre P. Massion, John T. Poirier, Gerard Brady, Fiona Blackhall, Dominic G. Rothwell, Charles M. Rudin, Caroline Dive
Publikováno v:
Nature Cancer. 3:1260-1270
Small cell lung cancer (SCLC) is characterized by morphologic, epigenetic and transcriptomic heterogeneity. Subtypes based upon predominant transcription factor expression have been defined that, in mouse models and cell lines, exhibit potential diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ade06cbcc732fedac0c0e8deec94e8f
https://doi.org/10.1038/s43018-022-00415-9
https://doi.org/10.1038/s43018-022-00415-9
Autor:
Triparna Sen, Charles M. Rudin, Richard P. Koche, Brian Loomis, John T. Poirier, Natasha Rekhtman, Marina K. Baine, Elisa de Stanchina, Juan Qiu, Helena A. Yu, Travis J. Hollmann, Michael H. Roehrl, Christine A. Iacobuzio-Donahue, Joachim Silber, Sonali Sinha, Marina Asher, Irina Linkov, Umesh K. Bhanot, Jacklynn Egger, Sam E. Tischfield, Jordana Ray-Kirton, Jason C. Chang, Michael Offin, Andrew Chow, Metamia Ciampricotti, Joseph M. Chan, Helen H. Won, Mark T.A. Donoghue, Parvathy Manoj, Fathema Uddin, Fanli Meng, Shweta S. Chavan, Maysun M. Hasan, Yingqian A. Zhan, Hirokazu Taniguchi, Alvaro Quintanal-Villalonga
Supplemental tables S1-S15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b59aeae9efc033bbf7f750d12903ac3
https://doi.org/10.1158/2159-8290.22540718
https://doi.org/10.1158/2159-8290.22540718
Autor:
Triparna Sen, Charles M. Rudin, Richard P. Koche, Brian Loomis, John T. Poirier, Natasha Rekhtman, Marina K. Baine, Elisa de Stanchina, Juan Qiu, Helena A. Yu, Travis J. Hollmann, Michael H. Roehrl, Christine A. Iacobuzio-Donahue, Joachim Silber, Sonali Sinha, Marina Asher, Irina Linkov, Umesh K. Bhanot, Jacklynn Egger, Sam E. Tischfield, Jordana Ray-Kirton, Jason C. Chang, Michael Offin, Andrew Chow, Metamia Ciampricotti, Joseph M. Chan, Helen H. Won, Mark T.A. Donoghue, Parvathy Manoj, Fathema Uddin, Fanli Meng, Shweta S. Chavan, Maysun M. Hasan, Yingqian A. Zhan, Hirokazu Taniguchi, Alvaro Quintanal-Villalonga
Lineage plasticity is implicated in treatment resistance in multiple cancers. In lung adenocarcinomas (LUAD) amenable to targeted therapy, transformation to small cell lung cancer (SCLC) is a recognized resistance mechanism. Defining molecular mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19866bcbfca6f0bd1b206c8dae81ff58
https://doi.org/10.1158/2159-8290.c.6549461
https://doi.org/10.1158/2159-8290.c.6549461
Autor:
Triparna Sen, Charles M. Rudin, Richard P. Koche, Brian Loomis, John T. Poirier, Natasha Rekhtman, Marina K. Baine, Elisa de Stanchina, Juan Qiu, Helena A. Yu, Travis J. Hollmann, Michael H. Roehrl, Christine A. Iacobuzio-Donahue, Joachim Silber, Sonali Sinha, Marina Asher, Irina Linkov, Umesh K. Bhanot, Jacklynn Egger, Sam E. Tischfield, Jordana Ray-Kirton, Jason C. Chang, Michael Offin, Andrew Chow, Metamia Ciampricotti, Joseph M. Chan, Helen H. Won, Mark T.A. Donoghue, Parvathy Manoj, Fathema Uddin, Fanli Meng, Shweta S. Chavan, Maysun M. Hasan, Yingqian A. Zhan, Hirokazu Taniguchi, Alvaro Quintanal-Villalonga
Supplemental figures and figure legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15cdf6100787567edd1d3c55a0d31bc8
https://doi.org/10.1158/2159-8290.22540724
https://doi.org/10.1158/2159-8290.22540724
Autor:
Gregory J. Riely, Natasha Rekhtman, Matthew D. Hellmann, Glenn Heller, Mark T.A. Donoghue, Barry S. Taylor, Charles M. Rudin, Tyler Jacks, Marc Ladanyi, Amanda Beras, Jennifer L. Sauter, Jason Chang, Yahya Daneshbod, Maria E. Arcila, Sonal Paul, Carla P. Concepcion, Jacklynn Egger, Hira Rizvi, Azadeh Namakydoust, Joseph Montecalvo, Jessica A. Lavery, Chai Bandlamudi, Adam J. Schoenfeld
Supplementary Legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dda3733d557902a8a12ccb977083657
https://doi.org/10.1158/1078-0432.22479309
https://doi.org/10.1158/1078-0432.22479309
Autor:
Charles M. Rudin, John T. Poirier, Triparna Sen, Richard P. Koche, Travis J. Hollmann, Elisa de Stanchina, Juan Qiu, Michael H. Roehrl, Marina Asher, Irina Linkov, Umesh Bhanot, Jacklynn Egger, Jordana Ray-Kirton, Metamia Ciampricotti, Michael Offin, Joseph M. Chan, Nisargbhai S. Shah, Parvathy Manoj, Viola Allaj, Fathema Uddin, Shweta S. Chavan, Yingqian A. Zhan, Andrew Chow, Yuan Hao, Hirokazu Taniguchi, Alvaro Quintanal-Villalonga
Small cell lung cancer (SCLC) is an aggressive malignancy characterized by early metastasis and extreme lethality. The backbone of SCLC treatment over the past several decades has been platinum-based doublet chemotherapy, with the recent addition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c17d25007f8e52491a30503597298025
https://doi.org/10.1158/0008-5472.c.6513732.v1
https://doi.org/10.1158/0008-5472.c.6513732.v1
Autor:
Charles M. Rudin, John T. Poirier, Triparna Sen, Richard P. Koche, Travis J. Hollmann, Elisa de Stanchina, Juan Qiu, Michael H. Roehrl, Marina Asher, Irina Linkov, Umesh Bhanot, Jacklynn Egger, Jordana Ray-Kirton, Metamia Ciampricotti, Michael Offin, Joseph M. Chan, Nisargbhai S. Shah, Parvathy Manoj, Viola Allaj, Fathema Uddin, Shweta S. Chavan, Yingqian A. Zhan, Andrew Chow, Yuan Hao, Hirokazu Taniguchi, Alvaro Quintanal-Villalonga
Subtype information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0570aeb3888803e658a600c7586ad1fb
https://doi.org/10.1158/0008-5472.22430859
https://doi.org/10.1158/0008-5472.22430859
Autor:
Gregory J. Riely, Natasha Rekhtman, Matthew D. Hellmann, Glenn Heller, Mark T.A. Donoghue, Barry S. Taylor, Charles M. Rudin, Tyler Jacks, Marc Ladanyi, Amanda Beras, Jennifer L. Sauter, Jason Chang, Yahya Daneshbod, Maria E. Arcila, Sonal Paul, Carla P. Concepcion, Jacklynn Egger, Hira Rizvi, Azadeh Namakydoust, Joseph Montecalvo, Jessica A. Lavery, Chai Bandlamudi, Adam J. Schoenfeld
Overall survival by combination of STK11, KEAP1, and SMARCA4 alteration status.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ec818030dc90fe8660d7d368364140
https://doi.org/10.1158/1078-0432.22479312
https://doi.org/10.1158/1078-0432.22479312
Autor:
Gregory J. Riely, Natasha Rekhtman, Matthew D. Hellmann, Glenn Heller, Mark T.A. Donoghue, Barry S. Taylor, Charles M. Rudin, Tyler Jacks, Marc Ladanyi, Amanda Beras, Jennifer L. Sauter, Jason Chang, Yahya Daneshbod, Maria E. Arcila, Sonal Paul, Carla P. Concepcion, Jacklynn Egger, Hira Rizvi, Azadeh Namakydoust, Joseph Montecalvo, Jessica A. Lavery, Chai Bandlamudi, Adam J. Schoenfeld
Purpose:SMARCA4 mutations are among the most common recurrent alterations in non–small cell lung cancer (NSCLC), but the relationship to other genomic abnormalities and clinical impact has not been established.Experimental Design:To characterize SM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6fa79eb27481fbd9afc8a67e3012aba
https://doi.org/10.1158/1078-0432.c.6530187
https://doi.org/10.1158/1078-0432.c.6530187
Autor:
Gregory J. Riely, Natasha Rekhtman, Matthew D. Hellmann, Glenn Heller, Mark T.A. Donoghue, Barry S. Taylor, Charles M. Rudin, Tyler Jacks, Marc Ladanyi, Amanda Beras, Jennifer L. Sauter, Jason Chang, Yahya Daneshbod, Maria E. Arcila, Sonal Paul, Carla P. Concepcion, Jacklynn Egger, Hira Rizvi, Azadeh Namakydoust, Joseph Montecalvo, Jessica A. Lavery, Chai Bandlamudi, Adam J. Schoenfeld
Frequency of altered individual genes within SMARCA4 Class 1 vs SMARCA4 Class 2 subgroups.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e926b8c5ea1c4082696b05c4906ffb2
https://doi.org/10.1158/1078-0432.22479306.v1
https://doi.org/10.1158/1078-0432.22479306.v1