Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jackline Wanjala"'
Autor:
Kaitlyn M. Gayvert, Etienne Dardenne, Cynthia Cheung, Mary Regina Boland, Tal Lorberbaum, Jackline Wanjala, Yu Chen, Mark A. Rubin, Nicholas P. Tatonetti, David S. Rickman, Olivier Elemento
Publikováno v:
Cell Reports, Vol 15, Iss 11, Pp 2348-2356 (2016)
Mutations in transcription factor (TF) genes are frequently observed in tumors, often leading to aberrant transcriptional activity. Unfortunately, TFs are often considered undruggable due to the absence of targetable enzymatic activity. To address th
Externí odkaz:
https://doaj.org/article/8e9b8a2da68647c39b32d5b33c481580
Autor:
Himisha Beltran, Howard I. Scher, Eva Undvall, Myriam Kossai, Susan F. Slovin, Juan Miguel Mosquera, Wouter R. Karthaus, James A. Eastham, Wei Di, Michael J. Morris, Sinan Ramazanoglu, Jackline Wanjala, Karim Touijer, Ian Vela, Brett S. Carver, Vincent P. Laudone, Zhen Cao, Charles L. Sawyers, Dong Gao, Leili Ran, Andrea Sboner, Hans Clevers, Daniel C. Danila, Yu Chen, Theresa Y MacDonald, Vivek K. Arora, Luendreo P Barboza, Qi Fan Zhang, Anuradha Gopalan, Dana E. Rathkopf, Ping Chi, Catherine Dowling, Inna Sirota, Kristen Rebecca Curtis, Stephen B. Solomon, Mark A. Rubin, Peter T. Scardino, Phillip J. Iaquinta, John Wongvipat
Publikováno v:
Cell, 159(1), 176-87. Elsevier B.V.
SummaryThe lack of in vitro prostate cancer models that recapitulate the diversity of human prostate cancer has hampered progress in understanding disease pathogenesis and therapy response. Using a 3D organoid system, we report success in long-term c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c12affb88731abd74664e34e69312ee
https://pubmed.ncbi.nlm.nih.gov/25551127
https://pubmed.ncbi.nlm.nih.gov/25551127
Autor:
Catherine Dowling, Hans Clevers, Charles L. Sawyers, Brett S. Carver, Mark A. Rubin, Howard I. Scher, Eva Undvall, Yu Chen, Dong Gao, Phillip J. Iaquinta, John Wongvipat, Stephen B. Solomon, Andrea Sboner, Ian Vela, Himisha Beltran, Juan Miguel Mosquera, Wouter R. Karthaus, Anuradha Gopalan, Jackline Wanjala, Myriam Kossai
Publikováno v:
Journal of Urology. 191
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce2ec026dddfb40236242e8cc890754c
https://doi.org/10.1016/j.juro.2014.02.910
https://doi.org/10.1016/j.juro.2014.02.910
Development of novel metastatic prostate cancer cell lines by 'organoid' in vitro culture technology
Autor:
Ian Vela, Dong Gao, Anuradha Gopalan, Andrea Sboner, Eva Undvall, Jackline Wanjala, Phillip Iaquinta, John Wongvipat, Wouter Karthaus, Hans Clevers, Stephen Barnett Solomon, Himisha Beltran, Myriam Kossai, Juan Miguel Mosquera, Mark A. Rubin, Brett Stewart Carver, Howard I. Scher, Charles L. Sawyers, Yu Chen
Publikováno v:
Journal of Clinical Oncology. 32:33-33
33 Background: The inability to propagate patient-derived prostate cancer cells in vitro is a major impediment in the mechanistic understanding of tumorigenesis and therapeutic response. In order to generate accurate in vitro models that represent th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29e1e1a5f649555f367fc20066652d29
https://doi.org/10.1200/jco.2014.32.4_suppl.33
https://doi.org/10.1200/jco.2014.32.4_suppl.33
Autor:
Etienne Dardenne, Olivier Elemento, David S. Rickman, Mark A. Rubin, Tal Lorberbaum, Kaitlyn Gayvert, Nicholas P. Tatonetti, Cynthia Cheung, Mary Regina Boland, Yu Chen, Jackline Wanjala
Publikováno v:
Cell Reports, Vol 15, Iss 11, Pp 2348-2356 (2016)
Mutations in transcription factors (TFs) genes are frequently observed in tumors, often leading to aberrant transcriptional activity. Unfortunately, TFs are often considered undruggable due to the absence of targetable enzymatic activity. To address
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::939c178d3d607c2d67e76bb02108d2b7