Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jackie de Belin"'
Autor:
Richard Harrop, Stuart Naylor, Michelle Kelleher, Peter Treasure, Gemma Bolton, William Shingler, Jackie de Belin
Publikováno v:
Cancer Immunology, Immunotherapy. 61:2283-2294
Cancer vaccines such as MVA-5T4 (TroVax(®)) must induce an efficacious immune response to deliver therapeutic benefit. The identification of biomarkers that impact on the clinical and/or immunological efficacy of cancer vaccines is required in order
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9edbe2c6c0d0fa0e5d602e1b6a12bfaa
https://doi.org/10.1007/s00262-012-1302-9
https://doi.org/10.1007/s00262-012-1302-9
Publikováno v:
Journal of Immunotherapy. 33:999-1005
The attenuated vaccinia virus MVA has been engineered to deliver the tumor antigen 5T4 (MVA-5T4; TroVax), a surface glycoprotein expressed by most solid tumors. MVA-5T4 has been tested in 2 phase I/II and 7 phase II clinical trials in colorectal (4 t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be2408a89168fb526798472fe0e35e22
https://doi.org/10.1097/cji.0b013e3181f5dac7
https://doi.org/10.1097/cji.0b013e3181f5dac7
Autor:
Stuart Naylor, Joan Hernandez-McClain, Robert J. Amato, Richard Harrop, Jackie de Belin, Madusha Goonewardena, J. P. Willis, Somyata Saxena, J. Jac, William Shingler
Publikováno v:
Journal of Immunotherapy. 32:765-772
Attenuated vaccinia virus, modified vaccinia Ankara (MVA) has been engineered to deliver the tumor antigen 5T4 (TroVax). MVA-5T4 has been evaluated in an open-label phase 2 trial in metastatic renal cell cancer patients in which the vaccine was admin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b63e990902f413a99c8fb2ab84b1e5a4
https://doi.org/10.1097/cji.0b013e3181ace876
https://doi.org/10.1097/cji.0b013e3181ace876
Autor:
James Miskin, Georgina Ferrige, Michelle Kelleher, Katie Binley, Vladimir Bantseev, Paul E. Miller, T Michael Nork, Diana Angell-Manning, Stuart Naylor, Peter Widdowson, Kyriacos A. Mitrophanous, Jackie de Belin, Julie Loader, Marie Carlucci, Margaret Esapa, Scott Ellis, Daniel Chipchase
Publikováno v:
Human gene therapy. 23(9)
RetinoStat(®) is an equine infectious anemia virus-based lentiviral gene therapy vector that expresses the angiostatic proteins endostatin and angiostatin that is delivered via a subretinal injection for the treatment of the wet form of age-related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0134cf5dfad7d5d56cfddfaf2ee4ad4
https://pubmed.ncbi.nlm.nih.gov/22716662
https://pubmed.ncbi.nlm.nih.gov/22716662
Autor:
Madusha Goonewardena, Stuart Naylor, Robert J. Amato, Richard Harrop, Robert E. Hawkins, Peter Treasure, Michelle Kelleher, Jackie de Belin, Howard L. Kaufman, William Shingler, M. McDonald
Publikováno v:
Cancer immunology, immunotherapy : CII. 60(6)
Few immunotherapy compounds have demonstrated a direct link between the predicted mode of action of the product and benefit to the patient. Since cancer vaccines are thought to have a delayed therapeutic effect, identification of the active moiety ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed9eda811b00faef980d5f54b30a418f
https://pubmed.ncbi.nlm.nih.gov/21387109
https://pubmed.ncbi.nlm.nih.gov/21387109
Autor:
Sarah Eastty, Piotr Tomczak, Howard L. Kaufman, William Shingler, M. McDonald, Stuart Naylor, Robert J. Amato, Richard Harrop, Madusha Goonewardena, Cezary Szczylik, Jackie de Belin, Robert E. Hawkins, John A. Thompson
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 16(22)
Purpose: The TroVax Renal Immunotherapy Survival Trial was a randomized, placebo-controlled phase III study that investigated whether modified vaccinia Ankara encoding the tumor antigen 5T4 (MVA-5T4) prolonged survival of patients receiving first-lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2846ed124ab67d40d7b49a7561bb2909
https://pubmed.ncbi.nlm.nih.gov/20881001
https://pubmed.ncbi.nlm.nih.gov/20881001
Autor:
Paul J, Adam, Joanne, Berry, Julie A, Loader, Kerry L, Tyson, Graham, Craggs, Paul, Smith, Jackie, De Belin, Graham, Steers, Francesco, Pezzella, Kris F, Sachsenmeir, Alasdair C, Stamps, Athula, Herath, Edith, Sim, Michael J, O'Hare, Adrian L, Harris, Jonathan A, Terrett
Publikováno v:
Molecular cancer research : MCR. 1(11)
Comparative two-dimensional proteome analysis was used to identify proteins differentially expressed in multiple clinical normal and breast cancer tissues. One protein, the expression of which was elevated in invasive ductal and lobular breast carcin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d4fe33d18f99241d92f5e7838cd89ef8
https://pubmed.ncbi.nlm.nih.gov/14517345
https://pubmed.ncbi.nlm.nih.gov/14517345
Autor:
Alcides Fernandes, Jiong Yan, Kyriacos A. Mitrophanous, Paul Wong, Martin Bussieres, James Miskin, Diana Angell-Manning, S. Iqball, Stuart Naylor, Julie Loader, Thomas M. Aaberg, Peter Widdowson, Jackie de Belin, Rando Allikmets, Mark Vezina, Jiong Kong, Michelle Kelleher, Marie Carlucci, Katie Binley, Scott Ellis, Peter Gouras, Annick Prefontaine, C. Bergstrom, Georgina Ferrige, Felicity Hurst
Publikováno v:
Investigative Opthalmology & Visual Science. 54:4061
Purpose StarGen is an equine infectious anemia virus (EIAV)-based lentiviral vector that expresses the photoreceptor-specific adenosine triphosphate (ATP)-binding cassette transporter (ABCA4) protein that is mutated in Stargardt disease (STGD1), a ju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96585ec57b0665d9ed96a72010645ef2
https://doi.org/10.1167/iovs.13-11871
https://doi.org/10.1167/iovs.13-11871