Výsledky vyhledávání - "Jackie Ruble"

Binding of the Novel Nonxanthine A 2A Adenosine Receptor Antagonist [ 3 H]SCH58261 to Coronary Artery Membranes

Autor: Ennio Ongini, John C. Shryock, Luiz Belardinelli, Stephen P. Baker, Donn M. Dennis, Angela Monopoli, Jackie Ruble, Silvio Dionisotti

Publikováno v: Circulation Research. 79:1153-1160

This study demonstrates quantification of A 2A adenosine receptors (A 2A AdoRs) in membranes prepared from porcine coronary arteries, porcine striatum, and PC12 cells. Radioligand binding assays were performed using the new selective A 2A AdoR antago

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f27178a5f0acc2fdd07e904462e6d517
https://doi.org/10.1161/01.res.79.6.1153

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Allosteric enhancer PD 81,723 acts by novel mechanism to potentiate cardiac actions of adenosine

Autor: Jackie Ruble, C Kollias-Baker, R F Bruns, J Linden, Donn M. Dennis, Luiz Belardinelli

Publikováno v: Circulation research. 75(6)

The 2-amino-3-benzoylthiophene derivative PD 81,723 is an allosteric enhancer of agonist binding to brain A1 adenosine receptors. One aim of this study was to characterize and contrast the effects of PD 81,723 on the A1 receptor-mediated negative dro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abfb020b40d6c925766265d178b08a19
https://pubmed.ncbi.nlm.nih.gov/7955150

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