Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jackie Akunda"'
Autor:
Laura Suter, Aliza Thompson, Ernie Harpur, Gerard Maurer, Bruno Flamion, Douglas C. Throckmorton, Phil Rossi, Jackie Akunda, Nancy Xu, Stefan Sultana, Federico Goodsaid, Jonathan A. Phillips, Sven A. Beushausen, Valérie G. Barlow, Denise Bounous, Jacky Vonderscher, David Gerhold, Sean P. Troth, Elizabeth Hausner, Karol L. Thompson, Matthew J. Schipper, Spiros Vamvakas, David Jacobson-Kram, William Taylor, Jean Marc Vidal, Beatriz Silva Lima, Albert F. Defelice, Supriya Jayadev, Magalie Guffroy, Yi Zhong Gu, James Eric McDuffie, Daniela Ennulat, Jeff Waring, Patricia Harlow, Leslie A. Obert, Sandra Snook, Frank D. Sistare, Eric A.G. Blomme, William B. Mattes, Craig P. Webb, Mark Pinches, David Honor, Romaldas Mačiulaitis, Myrtle Davis, Jinhe Lee, Frank Dieterle, Marisa Papaluca, Melanie Blank, Nathaniel Collins, William Baer, Peter L. Goering, Shen Xiao, Anthony J. Senagore, Krishna Prasad, Denise Robinson-Gravatt, Josef S Ozer, Eric Abadie, Graham Betton, Kevin Carl, Peter Kasper, David Laurie, Manisha Sonee, Dina Andrews-Cleavenger, Elizabeth G. Walker, Dan Holder, Markku Pasanen
Publikováno v:
Nature Biotechnology. 28:455-462
The first formal qualification of safety biomarkers for regulatory decision making marks a milestone in the application of biomarkers to drug development. Following submission of drug toxicity studies and analyses of biomarker performance to the Food
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153a6b13ac5e7fb2e36ce91685f63c53
https://doi.org/10.1038/nbt.1625
https://doi.org/10.1038/nbt.1625
Autor:
Howard F, Tiano, Charles D, Loftin, Jackie, Akunda, Christopher A, Lee, Judson, Spalding, Alisha, Sessoms, David B, Dunson, Eleanor G, Rogan, Scott G, Morham, Robert C, Smart, Robert, Langenbach
Publikováno v:
Cancer research. 62(12)
Nonsteroidal anti-inflammatory drugs are widely reported to inhibit carcinogenesis in humans and in rodents. These drugs are believed to act by inhibiting one or both of the known isoforms of cyclooxygenase (COX). However, COX-2, and not COX-1, is th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cdbdea48fef58f171e1aad52431901b2
https://pubmed.ncbi.nlm.nih.gov/12067981
https://pubmed.ncbi.nlm.nih.gov/12067981
Autor:
Lillian Sams, Leslie Brail, Sandaruwan Geeganage, Jackie Akunda, Rose T. Ajamie, Everett J. Perkins, Tao Wang, Sajan Joseph, Jianping Huang, George H. Rodgers
Publikováno v:
Cancer Research. 70:352-352
PI3K/AKT/mTOR/S6K signaling pathway (AKT pathway) controls cell survival, cell-cycle progression, cell growth and metabolism through a cascade phosphorylation of a number of key substrates. This pathway is regulated by three well characterized tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b787a17c79e74221694d941ad4a69d1c
https://doi.org/10.1158/1538-7445.am10-352
https://doi.org/10.1158/1538-7445.am10-352