Zobrazeno 1 - 10
of 342
pro vyhledávání: '"Jack. Gorski"'
Autor:
Sara E. Sabbagh, Dipica Haribhai, Jill A. Gershan, James Verbsky, James Nocton, Maryam Yassai, Elena N. Naumova, Erin Hammelev, Mahua Dasgupta, Ke Yan, Jack Gorski, Calvin B. Williams
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/1052c5151fa54bb9b97a939ee8a7ee29
Autor:
Sara E. Sabbagh, Dipica Haribhai, Jill A. Gershan, James Verbsky, James Nocton, Maryam Yassai, Elena N. Naumova, Erin Hammelev, Mahua Dasgupta, Ke Yan, Jack Gorski, Calvin B. Williams
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Recurrent exposures to a pathogenic antigen remodel the CD8+ T cell compartment and generate a functional memory repertoire that is polyclonal and complex. At the clonotype level, the response to the conserved influenza antigen, M158–66 has been we
Externí odkaz:
https://doaj.org/article/d54c6d29ecf14b399c9ea36992d8a7cf
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The immunologic significance of cross-reactivity of TCR recognition of peptide:MHC complexes is still poorly understood. We have described TCR cross-reactivity in a system involving polyclonal CD8 T cell recognition of the well characterized influenz
Externí odkaz:
https://doaj.org/article/5217aef3c4294308a828eba10c0827ef
Autor:
Elena N. Naumova, Maryam B. Yassai, Wendy Demos, Erica Reed, Melissa Unruh, Dipica Haribhai, Calvin B. Williams, Yuri N. Naumov, Jack Gorski
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
T-cell memory to pathogens can be envisioned as a receptor-based imprint of the pathogenic environment on the naïve repertoire of clonotypes. Recurrent exposures to a pathogen inform and reinforce memory, leading to a mature state. The complexity an
Externí odkaz:
https://doaj.org/article/a8af07e64edb48ed90dc940711435c30
Autor:
Clint Piper, Emma Hainstock, Cheng Yin-Yuan, Yao Chen, Achia Khatun, Moujtaba Y. Kasmani, John Evans, James A. Miller, Jack Gorski, Weiguo Cui, William R. Drobyski
Publikováno v:
Blood Advances. 6:2791-2804
Gastrointestinal (GI) tract involvement is a major determinant for subsequent morbidity and mortality arising during graft-versus-host disease (GVHD). CD4+ T cells that produce granulocyte-macrophage colony stimulating factor (GM-CSF) have emerged as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe4421185a06c90563fac6370f6b8b5
https://doi.org/10.1182/bloodadvances.2021006084
https://doi.org/10.1182/bloodadvances.2021006084
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 75(Supplement_1)
Vaccines against seasonal infections like influenza offer a recurring testbed, encompassing challenges in design, implementation, and uptake to combat a both familiar and ever-shifting threat. One of the pervading mysteries of influenza epidemiology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e16580ea47a53229b04a955ece2c4e
https://pubmed.ncbi.nlm.nih.gov/35607766
https://pubmed.ncbi.nlm.nih.gov/35607766
Autor:
Moujtaba Y Kasmani, Ashley E Ciecko, Ashley K Brown, Galina Petrova, Jack Gorski, Yi-Guang Chen, Weiguo Cui
Publikováno v:
Life science alliance. 5(10)
Type 1 diabetes (T1D) is an autoimmune disorder defined by CD8 T cell–mediated destruction of pancreatic β cells. We have previously shown that diabetogenic CD8 T cells in the islets of non-obese diabetic mice are phenotypically heterogeneous, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a81bd3f52c53c2876fa94629778991a5
https://pubmed.ncbi.nlm.nih.gov/35667687
https://pubmed.ncbi.nlm.nih.gov/35667687
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43509 (2012)
Invariant natural killer T (iNKT) cells develop in the thymus and branch off from the maturation pathway of conventional T cell at the DP stage. While different stages of iNKT cellular development have been defined, the actual time that iNKT cell pre
Externí odkaz:
https://doaj.org/article/57a01d041a6f48a7865e7d8feb8adcf4
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
Both CD28 and NKG2D can function as co-stimulatory receptors in human CD8+ T cells. However, their independent functional contributions in distinct CD8+ T cell subsets are not well understood. In this study, CD8+ T cells in human peripheral blood- an
Externí odkaz:
https://doaj.org/article/3887a1cb6d5d4edb98e4873d1d4657e7
Publikováno v:
PLoS ONE, Vol 3, Iss 11, p e3722 (2008)
HLA-DM (DM) mediates exchange of peptides bound to MHC class II (MHCII) during the epitope selection process. Although DM has been shown to have two activities, peptide release and MHC class II refolding, a clear characterization of the mechanism by
Externí odkaz:
https://doaj.org/article/9f01952b845e470388f7a6f638969609