Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jack Yongfeng Zhang"'
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0304086 (2024)
Recently, the first generic glucagon for injection was approved for the treatment of severe hypoglycemia. Unlike its brand name recombinant glucagon, the generic glucagon is synthetic. Since glucagon has a high propensity to form aggregates in soluti
Externí odkaz:
https://doaj.org/article/a5613d5b02c24ee7bf2bc5cb2171d8de
Publikováno v:
PLoS ONE, Vol 17, Iss 11, p e0277922 (2022)
Glucagon for Injection is a polypeptide hormone medication used to treat patients with severe hypoglycemia or low blood sugar. Only recently, was a generic version of glucagon for injection approved by the FDA. While the generic version was deemed eq
Externí odkaz:
https://doaj.org/article/3237e400655b4254a358bf34f9af3dcd
Publikováno v:
Molecules, Vol 27, Iss 22, p 7805 (2022)
Glucagon, a 29-amino acid polypeptide hormone, is an essential therapeutic agent used in the emergency treatment of hypoglycemia. However, glucagon is inherently unstable in aqueous solution. While glucagon equilibrates between unordered and the seco
Externí odkaz:
https://doaj.org/article/290c322889b140d680eae7dceac72e0e
Publikováno v:
Scientia Pharmaceutica, Vol 90, Iss 2, p 32 (2022)
Glucagon is a polypeptide hormone that serves as an essential therapeutic agent in the emergency treatment of hypoglycemia. Recently, the first generic glucagon for injection was approved. However, unlike its brand name counterpart, which is produced
Externí odkaz:
https://doaj.org/article/3ee7dcd6eb55469f92ed8151eba182ac
Autor:
Mary Z. Luo, Thomas R Murphy, Edward Kerwin, Jack Yongfeng Zhang, Donald P. Tashkin, George W. Bensch, Tony Marrs
Publikováno v:
Journal of Aerosol Medicine and Pulmonary Drug Delivery
Background: Two sequential single-dose crossover dose-ranging studies were performed to evaluate the clinical efficacy and safety profile of epinephrine hydrofluroalkane (HFA) metered-dose inhaler (MDI) formulation at various doses in subjects with a
Autor:
Jack Yongfeng Zhang, George W. Bensch, Edward Kerwin, David S. Pearlman, Phillip E. Korenblat, S. David Miller, Donald P. Tashkin, Mary Z. Luo, Leon S. Greos, Tony Marrs
Objective: A new epinephrine hydrofluoroalkane (HFA) asthma metered-dose inhaler (MDI) was reformulated to replace the previously marketed epinephrine chlorofluorocarbon (CFC) MDI. In addition to the HFA propellant change, several enhanced modificati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::342dd31fd8ce7ddec501bcf7cbcc9ddd
Publikováno v:
Pharmacology Research & Perspectives
Pharmacology Research & Perspectives, Vol 7, Iss 5, Pp n/a-n/a (2019)
Pharmacology Research & Perspectives, Vol 7, Iss 5, Pp n/a-n/a (2019)
Thymol is generally recognized as a safe substance by the FDA and has been widely used in the pharmaceutical, food, and cosmetic industries. Pharmacokinetic (PK) studies of thymol have been previously conducted for oral administration, but there has
Publikováno v:
Pharmacology Research & Perspectives
Pharmacology Research & Perspectives, Vol 7, Iss 5, Pp n/a-n/a (2019)
Pharmacology research & perspectives, vol 7, iss 5
Pharmacology Research & Perspectives, Vol 7, Iss 5, Pp n/a-n/a (2019)
Pharmacology research & perspectives, vol 7, iss 5
Epinephrine HFA (Primatene® Mist) is a newly formulated asthma metered dose inhaler developed to replace the previous Primatene® Mist CFC. The formulation of Epinephrine HFA contains thymol, a substance recognized to be safe by the FDA. Although th