Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jack Wellmerling"'
Autor:
Patrudu S. Makena, Rachael E. Rayner, G.L. Prasad, Jack Wellmerling, Estelle Cormet-Boyaka, Jing Zhao
Publikováno v:
Cell Biochemistry and Biophysics. 80:217-228
Cigarette smoke deregulates several biological pathways by modulating gene expression in airway epithelial cells and altering the physiology of the airway epithelium. The effects of repeated exposures of electronic cigarette delivery systems (ENDS) o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f484df79fc6c667d3c1d0ec52f894d7e
https://doi.org/10.1007/s12013-021-01042-4
https://doi.org/10.1007/s12013-021-01042-4
Autor:
Amanda B. Hummon, Dehua Pei, Amritendu Koley, Jessica K Lukowski, Estelle Cormet-Boyaka, Jack Wellmerling, Patrick G Dougherty
Publikováno v:
J Med Chem
Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, encoding for a chloride ion channel. Membrane expression of CFTR is negatively regulated by CFTR-associated ligand (CAL). We previousl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16c9736ca5455a241d397e6d370d5c9b
https://doi.org/10.1021/acs.jmedchem.0c01528
https://doi.org/10.1021/acs.jmedchem.0c01528
Autor:
Jack Wellmerling, Rachael E. Rayner, Sheng‐Wei Chang, Elizabeth L. Kairis, Sun Hee Kim, Amit Sharma, Prosper N. Boyaka, Estelle Cormet‐Boyaka
Publikováno v:
FASEB J
Mutations in the CFTR gene lead to cystic fibrosis, a genetic disease associated with chronic infection and inflammation and ultimately respiratory failure. The most common CF-causing mutation is F508del and CFTR modulators (correctors and potentiato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd8ee0dd2eeb1070a44d3215fb288c1
https://pubmed.ncbi.nlm.nih.gov/35412656
https://pubmed.ncbi.nlm.nih.gov/35412656
Autor:
Jack Wellmerling, Estelle Cormet-Boyaka, Michael T. Borchers, Eunsoo Kim, Sheng-Wei Chang, Prosper N. Boyaka, Wissam Osman
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-6 (2019)
Respiratory Research
Respiratory Research
Chronic Obstructive Pulmonary Disease (COPD) is a complex disease resulting in respiratory failure and represents the third leading cause of global death. The two classical phenotypes of COPD are chronic bronchitis and emphysema. Owing to similaritie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d27309974a08c14cdc92d7b2d6e2a768
http://link.springer.com/article/10.1186/s12931-019-1170-3
http://link.springer.com/article/10.1186/s12931-019-1170-3
Autor:
Larry S. Schlesinger, Jack Wellmerling, Estelle Cormet-Boyaka, Frank Robledo-Avila, Shuzhong Zhang, Santiago Partida-Sanchez, Susan D. Reynolds, Benjamin T. Kopp, Kaivon Assani, Hannah Rinehardt, Chandra L. Shrestha
Publikováno v:
Journal of Cystic Fibrosis. 18:622-629
Background There are no effective treatments for Burkholderia cenocepacia in patients with cystic fibrosis (CF) due to bacterial multi-drug resistance and defective host killing. We demonstrated that decreased bacterial killing in CF is caused by red
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c1f1f275504e714dfe0022457db9149
https://doi.org/10.1016/j.jcf.2018.10.010
https://doi.org/10.1016/j.jcf.2018.10.010
Autor:
David A. Yeung, Ramesh K. Ganju, Carolyn Wang, Brent A. Weiss, Subhadip Das, Anjum Sohail, Andrew B. Herr, Nirvan Shanker, Jeanette L.C. Miller, Jack Wellmerling, Gunjan Agarwal, Rafael Fridman
Publikováno v:
Journal of Molecular Biology. 431:368-390
Discoidin domain receptors (DDR1 and DDR2) are receptor tyrosine kinases that signal in response to collagen. We had previously shown that collagen binding leads to clustering of DDR1b, a process partly mediated by its extracellular domain (ECD). In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cdf371d97153d3ae458e6d2493afc51
https://doi.org/10.1016/j.jmb.2018.11.015
https://doi.org/10.1016/j.jmb.2018.11.015
Autor:
Rachael E. Rayner, Wissam Osman, Xiaoli Zhang, Prosper N. Boyaka, Amal O. Amer, Mark E. Peeples, Jack Wellmerling, Sheng-Wei Chang, Sara Mertz, Estelle Cormet-Boyaka
Publikováno v:
Biochimica et biophysica acta. General subjects. 1862(9)
Background Marijuana consumption is on the rise in the US but the health benefits of cannabis smoking are controversial and the impact of cannabis components on lung homeostasis is not well-understood. Lung function requires a fine regulation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460eeb8967f35d6ed78b1f09549a446b
https://pubmed.ncbi.nlm.nih.gov/29928919
https://pubmed.ncbi.nlm.nih.gov/29928919