Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jack V W Bacon"'
Autor:
Elie J. Ritch, Cameron Herberts, Evan W. Warner, Sarah W. S. Ng, Edmond M. Kwan, Jack V. W. Bacon, Cecily Q. Bernales, Elena Schönlau, Nicolette M. Fonseca, Veda N. Giri, Corinne Maurice-Dror, Gillian Vandekerkhove, Steven J. M. Jones, Kim N. Chi, Alexander W. Wyatt
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-11 (2023)
Abstract Specific classes of DNA damage repair (DDR) defect can drive sensitivity to emerging therapies for metastatic prostate cancer. However, biomarker approaches based on DDR gene sequencing do not accurately predict DDR deficiency or treatment b
Externí odkaz:
https://doaj.org/article/857049a6c5d347b5818113b423d91b16
Autor:
Jack V W Bacon, Patrizia Giannatempo, Giovanna Cataldo, Ladan Fazli, Neetu Saxena, Guliz Ozgun, Maryam Soleimani, Kim Chi, Craig Nichols, Andrea Necchi, Alexander W Wyatt, Christian K Kollmannsberger, Lucia Nappi
Publikováno v:
The Oncologist. 27:e912-e915
Background Primary mediastinal nonseminoma germ cell tumors (PMNSGCT) are a subgroup of nonseminoma germ cell tumors (GCT) with poor prognosis. In this study, PMNSGCT-specific genomic landscape was analyzed and correlated with clinical outcomes. Meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32ebd859f04fcb1ba44be6b12031a662
https://doi.org/10.1093/oncolo/oyac197
https://doi.org/10.1093/oncolo/oyac197
Autor:
Cameron, Herberts, Matti, Annala, Joonatan, Sipola, Sarah W S, Ng, Xinyi E, Chen, Anssi, Nurminen, Olga V, Korhonen, Aslı D, Munzur, Kevin, Beja, Elena, Schönlau, Cecily Q, Bernales, Elie, Ritch, Jack V W, Bacon, Nathan A, Lack, Matti, Nykter, Rahul, Aggarwal, Eric J, Small, Martin E, Gleave, David A, Quigley, Felix Y, Feng, Kim N, Chi, Alexander W, Wyatt
Publikováno v:
Nature. 608(7921)
Circulating tumour DNA (ctDNA) in blood plasma is an emerging tool for clinical cancer genotyping and longitudinal disease monitoring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a7ddec5f113168d9b90e80055f3539ac
https://pubmed.ncbi.nlm.nih.gov/35859180
https://pubmed.ncbi.nlm.nih.gov/35859180
Autor:
Jean-Michel Lavoie, Jack V. W. Bacon, Matti Annala, Alexander W. Wyatt, Christian Kollmannsberger, Ladan Fazli, Lucia Nappi, Gang Wang, Alan So, Maryam Soleimani, Kim N. Chi, Martin E. Gleave
Publikováno v:
Clinical genitourinary cancer. 18(4)
Background There is a lack of molecularly-informed biomarkers for patients with metastatic renal cell carcinoma (RCC). Plasma cell-free DNA (cfDNA) sequencing is a minimally-invasive alternative to tissue for profiling the genome in other cancers but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18718df30317f4a833a2b17ed495a6a6
https://pubmed.ncbi.nlm.nih.gov/32046920
https://pubmed.ncbi.nlm.nih.gov/32046920
Autor:
Tobias Zellweger, Jack V. W. Bacon, Alexander W. Wyatt, Spasenija Savic Prince, Kirsten D. Mertz, Clémentine Le Magnen, Tatjana Vlajnic, Hans-Helge Seifert, Christian Ruiz, Joel R Federer-Gsponer, Sarah G. Dugas, David C Müller, Cyrill A. Rentsch, Lukas Bubendorf
Publikováno v:
Cancer cytopathologyReferences. 127(9)
BACKGROUND Mutations of AT-rich interactive domain 1 (ARID1A) have been associated with a worse outcome after intravesical treatment with bacille Calmette-Guerin in patients with non-muscle-invasive bladder cancer (NMIBC). Loss of ARID1A protein expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6335e2ed409298d2b97658147bb0c19f
https://pubmed.ncbi.nlm.nih.gov/32386279
https://pubmed.ncbi.nlm.nih.gov/32386279
Autor:
Sarah G. Dugas, H. Seifert, Matti Annala, Peter C. Black, David C Müller, Alexander W. Wyatt, Cyrill A. Rentsch, Elie Ritch, Gillian Vandekerkhove, Lukas Bubendorf, Jack V. W. Bacon
Publikováno v:
European Urology. 79:S617
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18793d561581f103a195beba142d3328
https://doi.org/10.1016/s0302-2838(21)00828-9
https://doi.org/10.1016/s0302-2838(21)00828-9
Autor:
Jack V. W. Bacon, Christian Kollmannsberger, Ladan Fazli, Alan I. So, Maryam Soleimani, Alexander W. Wyatt, Lucia Nappi, Matti Annala, Jean-Michel Lavoie, Kim N. Chi, Martin E. Gleave
Publikováno v:
Clinical Cancer Research. 26:A18-A18
Despite the recent implementation of novel targeted therapies, the 5-year survival rate for metastatic renal cell carcinoma (mRCC) remains dismal. Prognostic and predictive biomarkers are urgently required to avoid unnecessary patient morbidity and f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d3e5496036a35dd1f486322b6cc76d5
https://doi.org/10.1158/1557-3265.liqbiop20-a18
https://doi.org/10.1158/1557-3265.liqbiop20-a18
Autor:
Kevin Beja, Matti Nykter, Gillian Vandekerkhove, Matti Annala, Sinja Taavitsainen, Kim N. Chi, Jack V. W. Bacon, Alexander W. Wyatt
Publikováno v:
Communications Biology, Vol 1, Iss 1, Pp 1-8 (2018)
Prostate cancer has a low somatic mutation rate but non-coding regions remain underexplored. We sequenced the untranslated regions (UTRs) of 72 established driver genes in 428 patients with metastatic prostate cancer and identified FOXA1 3′-UTR mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d408f7ab306ba32f31f5c43b48d4c04c
https://doi.org/10.1038/s42003-018-0128-1
https://doi.org/10.1038/s42003-018-0128-1
Autor:
Srikala S. Sridhar, Gillian Vandekerkhove, Michael Ong, Jack V. W. Bacon, Sebastien J. Hotte, Joel Roger Gingerich, Gregory Lo, Carmel Pezaro, Arun Azad, Sinja Taavitsainen, Joseph D. Ruether, Lori Wood, Alexander W. Wyatt, Deepa Wadhwa, Cristiano Ferrario, Ben Tran, Kim N. Chi, Matti Annala, Nayyer Iqbal, Scott North
Publikováno v:
Journal of Clinical Oncology. 37:5003-5003
5003 Background: The treatment for poor prognosis mCRPC includes taxanes and androgen receptor (AR) targeted therapy, however the optimal treatment is undefined. Methods: Patients (pts) with poor prognosis (liver metastases, early CRPC ( < 12 months
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef4ec4c56d804efd4635954132a45dd8
https://doi.org/10.1200/jco.2019.37.15_suppl.5003
https://doi.org/10.1200/jco.2019.37.15_suppl.5003
Autor:
Jack V. W. Bacon, Kim N. Chi, Jean-Michel Lavoie, Christian Kollmannsberger, Alexander W. Wyatt, Lucia Nappi, Matti Annala, Maryam Soleimani
Publikováno v:
Journal of Clinical Oncology. 37:e16105-e16105
e16105 Background: Clear cell renal cell carcinoma (ccRCC) represents the most common presentation of kidney cancer. Patient outcomes have significantly improved with the approval of several targeted agents over the past decade. However, the lack of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a386d31f11c9024c90c3ab4272c3e480
https://doi.org/10.1200/jco.2019.37.15_suppl.e16105
https://doi.org/10.1200/jco.2019.37.15_suppl.e16105