Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Jack T. Saari"'
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. 223:282-287
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1db1e21ff8eb0d7a8d7501ded46da1a
https://doi.org/10.1111/j.1525-1373.2000.22340.x
https://doi.org/10.1111/j.1525-1373.2000.22340.x
Autor:
Ann M. Bode, Alex B. Lentsch, Hanqian L. Carlson, Loren E. Wold, Dale A. Schuschke, Jack T. Saari, Huawei Zeng, Jun Ren, Jinhong Duan
Publikováno v:
The Journal of Nutritional Biochemistry. 18:443-448
Dietary copper (Cu) deficiency leads to cardiac morphological and functional defects suggestive of heart failure. However, simultaneous cytoprotective events also appear to occur. The molecular mechanisms responsible for this complex alteration of ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::831e91e2977e4c17cf2d8c03420f1b97
https://doi.org/10.1016/j.jnutbio.2006.07.006
https://doi.org/10.1016/j.jnutbio.2006.07.006
Publikováno v:
The Journal of Nutrition. 137:1370-1374
The purpose of this study was to determine the effects of copper deficiency on key aspects of homocysteine metabolism that involve methionine recycling and transsulfuration. Male weanling Sprague-Dawley rats were fed AIN-93G-based diets containing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c323ef2ca95f1721939ffcb1add314a
https://doi.org/10.1093/jn/137.6.1370
https://doi.org/10.1093/jn/137.6.1370
Autor:
Jack T. Saari, Lucy B. Esberg, Henry C. Lukaski, Edward C. Carlson, W. Thomas Johnson, Jun Ren, David P. Relling, Eric J. Murphy
Publikováno v:
Obesity. 15:1242-1257
High-fat and marginally copper-deficient diets impair heart function, leading to cardiac hypertrophy, increased lipid droplet volume, and compromised contractile function, resembling lipotoxic cardiac dysfunction. However, the combined effect of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9256f297f502fbc7a3930bb1e47893b
https://doi.org/10.1038/oby.2007.146
https://doi.org/10.1038/oby.2007.146
Autor:
Jack T. Saari, Suresh C. Tyagi, Walter E. Rodriguez, Zhanxiang Zhou, Chang Xiao, Youchun Jiang, Wenke Feng, Corey L. Reynolds, Y. James Kang, John W. Eaton
Publikováno v:
The Journal of Experimental Medicine
Sustained pressure overload causes cardiac hypertrophy and the transition to heart failure. We show here that dietary supplementation with physiologically relevant levels of copper (Cu) reverses preestablished hypertrophic cardiomyopathy caused by pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89fa1f4820821c4cf6c5dd9992ea0a4e
https://doi.org/10.1084/jem.20061943
https://doi.org/10.1084/jem.20061943
Publikováno v:
Journal of Inorganic Biochemistry. 100:186-191
It has been well documented that dietary copper (Cu) deficiency causes a hypertrophic cardiomyopathy in rodent models. However, a possible alteration in gene expression has not been fully examined. The present study was undertaken to determine the ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0274371cca36dc558370391e04c132e7
https://doi.org/10.1016/j.jinorgbio.2005.11.002
https://doi.org/10.1016/j.jinorgbio.2005.11.002
Publikováno v:
The American Journal of Pathology. 167:337-344
Alcohol-induced cardiomyopathy including fibrosis has been recognized clinically for a long time, but its pathogenesis is incompletely understood. Studies using experimental animals have not fully duplicated the pathological changes in humans, and an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f32f4079d52bbb0490426d192a5176ae
https://doi.org/10.1016/s0002-9440(10)62979-3
https://doi.org/10.1016/s0002-9440(10)62979-3
Zinc Supplementation Prevents Alcoholic Liver Injury in Mice through Attenuation of Oxidative Stress
Publikováno v:
The American Journal of Pathology. 166:1681-1690
Alcoholic liver disease is associated with zinc decrease in the liver. Therefore, we examined whether dietary zinc supplementation could provide protection from alcoholic liver injury. Metallothionein-knockout and wild-type 129/Sv mice were pair-fed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad780d87a487206838a3f909333fd0af
https://doi.org/10.1016/s0002-9440(10)62478-9
https://doi.org/10.1016/s0002-9440(10)62478-9
Publikováno v:
Nutrition Research. 25:177-186
Short-term severe copper deficiency has been shown to significantly reduce acetylcholine (Ach)-induced vascular smooth muscle relaxation. The current study was designed to examine the long-term relationship of marginal dietary Cu to vasoreactivity. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee86ba0a2b28fade9761b563a822000e
https://doi.org/10.1016/j.nutres.2004.11.001
https://doi.org/10.1016/j.nutres.2004.11.001
Publikováno v:
Experimental Biology and Medicine. 229:616-622
Dietary copper (Cu) restriction leads to cardiac hypertrophy and failure in mice, and Cu repletion (CuR) reverses the hypertrophy and prevents the transition to heart failure. The present study was undertaken to determine changes in myocardial gene e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21a33431984fe6448b9db8b527804507
https://doi.org/10.1177/153537020422900705
https://doi.org/10.1177/153537020422900705