Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jack Sublett"'
Autor:
Xiuling Li, Rong Qi, Chunliang Li, Virginia Valentine, Hartmut Berns, Amanda Balch, Marcus B. Valentine, Charles J. Sherr, Judith Hyle, Rebecca Singleterry, Jack Sublett
Publikováno v:
Molecular and Cellular Biology. 34:1649-1658
Injection of transcription activator-like effector nucleases (TALEN) mRNAs into mouse zygotes transferred into foster mothers efficiently generated founder mice with heritable mutations in targeted genes. Immunofluorescence visualization of phosphory
Publikováno v:
Infection, Genetics and Evolution. 7:708-716
In the United States, Streptococcus pneumoniae is the leading cause of community-acquired pneumonia and invasive bacterial disease. As antimicrobial resistance increases, it will become critical to determine if strains circulating in a population are
Autor:
Jack Sublett, Theresa Barton, Deepak Kaushal, Carlos J. Orihuela, Elaine Tuomanen, Caroline Obert, Ernesto Hinojosa
Publikováno v:
Infection and Immunity. 74:4766-4777
Streptococcus pneumoniae is a leading cause of community-acquired pneumonia and gram-positive sepsis. While multiple virulence determinants have been identified, the combination of features that determines the propensity of an isolate to cause invasi
Autor:
Jack Sublett, Timo K. Korhonen, Jenni Antikainen, Geli Gao, Carlos J. Orihuela, Beth Mann, Elaine Tuomanen
Publikováno v:
Infection and Immunity. 74:821-829
Members of the choline binding protein (Cbp) family are noncovalently bound to phosphorylcholine residues on the surface of Streptococcus pneumoniae . It has been suggested that CbpG plays a role in adherence and increase virulence both at the mucosa
Publikováno v:
American Journal of Surgical Pathology. 29:579-587
The diagnosis of prostatic carcinoma and especially minimal prostatic carcinoma can sometimes be challenging on needle core biopsy and occasionally immunohistochemistry is an aid in the diagnosis. Immunostains, such as those directed against the basa
Publikováno v:
Journal of Bacteriology. 186:8463-8471
Vancomycin is used increasingly to treat invasive infections caused by multidrug-resistant Streptococcus pneumoniae . Although no vancomycin-resistant strains have been isolated to date, tolerant strains that fail to die rapidly and that cause relaps
Autor:
Juan Li, Carina A. Rodriguez, Cynthia G. Whitney, Elaine Tuomanen, Kathryn M. Edwards, Lauren Mitchell, Robyn M. Atkinson, Chin-Shang Li, Jack Sublett, P. Joan Chesney, Tiebin Liu, Wally Bitar
Publikováno v:
The Journal of Infectious Diseases. 190:1481-1487
BACKGROUND: Vancomycin is often added to therapy for meningitis caused by Streptococcus pneumoniae. Tolerant bacteria without classic resistance that escape killing by multiple antibiotics have been reported sporadically. We determined the prevalence
Publikováno v:
Infection and Immunity. 72:5582-5596
Streptococcus pneumoniae is a leading cause of invasive bacterial disease. This is the first study to examine the expression of S. pneumoniae genes in vivo by using whole-genome microarrays available from The Institute for Genomic Research. Total RNA
Autor:
Ingrid Andersson, Jenny Fernebro, Staffan Normark, Eva Morfeldt, Birgitta Henriques Normark, Rodger Novak, Jack Sublett, Elaine Tuomanen
Publikováno v:
The Journal of Infectious Diseases. 189:328-338
Penicillin and vancomycin induce a lytic response in Streptococcus pneumoniae that requires the N-acetylmuramyl-l-alanine amidase LytA. We show that clinical isolates of pneumococci of capsular serotypes 1, 4, 6B, and 23F were generally less lytic to
Autor:
Elaine Tuomanen, Johann S. Braun, Timothy J. Mitchell, Jack Sublett, Joerg R. Weber, Dorette Freyer, John L. Cleveland
Publikováno v:
Journal of Clinical Investigation. 109:19-27
Pneumococcus is the most common and aggressive cause of bacterial meningitis and induces a novel apoptosis-inducing factor-dependent (AIF-dependent) form of brain cell apoptosis. Loss of production of two pneumococcal toxins, pneumolysin and H(2)O(2)