Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jack Strominger"'
Autor:
Feng Tian, Wenlong Yang, Daniel A. Mordes, Jin-Yuan Wang, Johnny S. Salameh, Joanie Mok, Jeannie Chew, Aarti Sharma, Ester Leno-Duran, Satomi Suzuki-Uematsu, Naoki Suzuki, Steve S. Han, Fa-Ke Lu, Minbiao Ji, Rosanna Zhang, Yue Liu, Jack Strominger, Neil A. Shneider, Leonard Petrucelli, X. Sunney Xie, Kevin Eggan
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Sensitive and label-free imaging methods to visualize nerve degeneration are currently lacking. Here authors show that stimulated Raman scattering (SRS) microscopy can be used to monitor peripheral nerve degeneration in mouse models of amyotrophic la
Externí odkaz:
https://doaj.org/article/60127ef2c8cc4a6295abca6013b56613
Autor:
Leonardo Ferreira, Torsten Meissner, Tarjei Mikkelsen, Charles O'Donnell, Richard Sherwood, William Mallard, John Rinn, Chad Cowan, Jack Strominger
Publikováno v:
The Journal of Immunology. 194:60.7-60.7
Human pregnancy poses an immunological paradox: at the fetal-maternal interface, semi-allogeneic fetal extravillous trophoblasts (EVT) invade the uterine mucosa without being rejected by the maternal immune system. HLA-G is a nonclassical MHC class I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a59ddaf3435b463f2489e19a524bd2e
https://doi.org/10.4049/jimmunol.194.supp.60.7
https://doi.org/10.4049/jimmunol.194.supp.60.7
Publikováno v:
The Journal of Immunology. 194:65.7-65.7
A unique challenge for maternal immune cells during pregnancy is to tolerate an allogeneic fetus, and yet to remain competent to respond to invading pathogens. CD8+ effector T cells play a key role in protection against virus infections and may direc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5a2170b266e44afb98a67a2474e739a
https://doi.org/10.4049/jimmunol.194.supp.65.7
https://doi.org/10.4049/jimmunol.194.supp.65.7
Publikováno v:
The Journal of Immunology. 194:65.4-65.4
Invading HLA-G+ extravillous trophoblasts (EVT) are believed to play a key role in the prevention of a maternal immune attack on foreign fetal tissues. EVT are difficult to study due to their low frequency and lack of proliferative capacity. Here hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdaaab1ae571fb02443af1fb4d505b81
https://doi.org/10.4049/jimmunol.194.supp.65.4
https://doi.org/10.4049/jimmunol.194.supp.65.4
Publikováno v:
The Journal of Immunology. 194:65.5-65.5
The interaction of non-cytotoxic decidual NK cells (dNK) and extravillous trophoblasts (EVT) at the fetal-maternal interface has been studied. Confocal microscopy revealed that many dNK can interact with a single large EVT, leading to the formation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a21bb1be7766fc3b03cadb68faac684
https://doi.org/10.4049/jimmunol.194.supp.65.5
https://doi.org/10.4049/jimmunol.194.supp.65.5
Publikováno v:
The Journal of Immunology. 194:140.28-140.28
Recent advances in stem cell biology have made it possible to contemplate the use of a patient’s own cells as an unlimited source for transplantation. Unfortunately, the generation of iPSCs remains a costly, time consuming and highly variable proce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7aef73b70a1160614fa2e9e0a40c719e
https://doi.org/10.4049/jimmunol.194.supp.140.28
https://doi.org/10.4049/jimmunol.194.supp.140.28
Publikováno v:
The Journal of Immunology. 192:197.8-197.8
Decidual natural killer cells (dNK) are the most abundant lymphocytes at the fetal-maternal interface. dNK have been shown to have limited cytotoxic capacity but secrete high levels of cytokines to facilitate extravillous trophoblast (EVT) invasion.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::426e9095044c523288cdb0b5697dd8ab
https://doi.org/10.4049/jimmunol.192.supp.197.8
https://doi.org/10.4049/jimmunol.192.supp.197.8
Autor:
Sze-Ling Ng, Jack Strominger
Publikováno v:
The Journal of Immunology. 192:136.11-136.11
Autoimmune diseases occur when there is misregulation within the immune system. Regulatory T cells (Tregs) are critical for the regulation of this immune response, however, little is known about their own regulation. The induction and activation of T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c98e33a35ee24f8087b108120e3b2db8
https://doi.org/10.4049/jimmunol.192.supp.136.11
https://doi.org/10.4049/jimmunol.192.supp.136.11
Autor:
Tamara Tilburgs, Jack Strominger
Publikováno v:
The Journal of Immunology. 190:69.24-69.24
INTRODUCTION: During pregnancy HLA-G+ extravillous trophoblasts (EVTs) play a key role in the prevention of a maternal immune attack to allogeneic fetal tissue. Human EVTs are extremely difficult to study due to their low frequency and lack of prolif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddb5ae607426961e22ac26935a345a32
https://doi.org/10.4049/jimmunol.190.supp.69.24
https://doi.org/10.4049/jimmunol.190.supp.69.24